Poly-ADP-Ribose Binding Proteins
                             
                            
                            
                                
                                    
                                            
	"Poly-ADP-Ribose Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				Proteins that contain POLY-ADP RIBOSE BINDING MOTIFS. They include HISTONES and other proteins that function in DNA REPAIR, replication, gene transcription, and APOPTOSIS.
    
			
			
				
				
					
						| Descriptor ID | D000075223 | 
					
						| MeSH Number(s) | D12.776.157.687 D12.776.660.720 | 
					
						| Concept/Terms | Poly-ADP-Ribose Binding ProteinsPoly-ADP-Ribose Binding ProteinsBinding Proteins, Poly-ADP-RibosePoly ADP Ribose Binding ProteinspADPr-Binding ProteinspADPr Binding Proteins
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				Below are MeSH descriptors whose meaning is more general than "Poly-ADP-Ribose Binding Proteins".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Poly-ADP-Ribose Binding Proteins".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Poly-ADP-Ribose Binding Proteins" by people in this website by year, and whether "Poly-ADP-Ribose Binding Proteins" was a major or minor topic of these publications. 
				
					 
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 2000 | 0 | 1 | 1 | 
| 2001 | 0 | 1 | 1 | 
| 2002 | 0 | 2 | 2 | 
| 2005 | 0 | 1 | 1 | 
| 2007 | 0 | 1 | 1 | 
| 2010 | 0 | 1 | 1 | 
| 2012 | 0 | 1 | 1 | 
| 2013 | 0 | 1 | 1 | 
| 2014 | 0 | 1 | 1 | 
| 2015 | 0 | 2 | 2 | 
| 2016 | 0 | 1 | 1 | 
| 2017 | 1 | 3 | 4 | 
| 2018 | 1 | 0 | 1 | 
| 2019 | 1 | 0 | 1 | 
| 2020 | 0 | 1 | 1 | 
| 2022 | 1 | 1 | 2 | 
| 2023 | 0 | 1 | 1 | 
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				Below are the most recent publications written about "Poly-ADP-Ribose Binding Proteins" by people in Profiles.
						
					
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								Comprehensive molecular characterization of early stage grade 3 endometrioid endometrial adenocarcinoma. Gynecol Oncol. 2024 Oct; 189:138-145. 
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								Immune checkpoint inhibitors for POLE or POLD1 proofreading-deficient metastatic colorectal cancer. Ann Oncol. 2024 Jul; 35(7):643-655. 
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								Defining the subset of mutations in polymerase epsilon (POLE) associated with loss-of-proofreading (LOP) functionality. Ann Oncol. 2024 Jul; 35(7):678-680. 
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								c-Jun N-Terminal Kinase Promotes Stress Granule Assembly and Neurodegeneration in C9orf72-Mediated ALS and FTD. J Neurosci. 2023 04 26; 43(17):3186-3197. 
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								De novo variants in genes regulating stress granule assembly associate with neurodevelopmental disorders. Sci Adv. 2022 08 19; 8(33):eabo7112. 
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								Clinical and Molecular Characterization of POLE Mutations as Predictive Biomarkers of Response to Immune Checkpoint Inhibitors in Advanced Cancers. JCO Precis Oncol. 2022 02; 6:e2100267. 
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								TDRD3 is an antiviral restriction factor that promotes IFN signaling with G3BP1. PLoS Pathog. 2022 01; 18(1):e1010249. 
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								Myelodysplastic syndrome with t(6;9)(p22;q34.1)/DEK-NUP214 better classified as acute myeloid leukemia? A multicenter study of 107 cases. Mod Pathol. 2021 06; 34(6):1143-1152. 
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								Composition-dependent thermodynamics of intracellular phase separation. Nature. 2020 05; 581(7807):209-214. 
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								Mechanisms and clinical course of cardiovascular toxicity of cancer treatment I. Oncology. Semin Oncol. 2019 12; 46(6):397-402.