"Telomerase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An essential ribonucleoprotein reverse transcriptase that adds telomeric DNA to the ends of eukaryotic CHROMOSOMES.
Descriptor ID |
D019098
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MeSH Number(s) |
D08.811.913.696.445.308.300.750.750 D12.776.157.687.613 D12.776.157.725.500.921 D12.776.660.720.613 D12.776.664.962.500.921
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Concept/Terms |
Telomerase- Telomerase
- Telomerase Reverse Transcriptase
- Reverse Transcriptase, Telomerase
- Transcriptase, Telomerase Reverse
Telomerase Catalytic Subunit- Telomerase Catalytic Subunit
- Catalytic Subunit, Telomerase
- Subunit, Telomerase Catalytic
- Telomerase Reverse Transcriptase Catalytic Subunit
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Below are MeSH descriptors whose meaning is more general than "Telomerase".
Below are MeSH descriptors whose meaning is more specific than "Telomerase".
This graph shows the total number of publications written about "Telomerase" by people in this website by year, and whether "Telomerase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 1 | 1 | 2 |
1997 | 3 | 1 | 4 |
1999 | 2 | 0 | 2 |
2001 | 4 | 0 | 4 |
2002 | 0 | 2 | 2 |
2003 | 2 | 1 | 3 |
2004 | 2 | 3 | 5 |
2005 | 0 | 2 | 2 |
2006 | 3 | 2 | 5 |
2007 | 2 | 0 | 2 |
2009 | 0 | 2 | 2 |
2010 | 3 | 2 | 5 |
2011 | 3 | 3 | 6 |
2012 | 2 | 3 | 5 |
2013 | 2 | 3 | 5 |
2014 | 3 | 8 | 11 |
2015 | 3 | 3 | 6 |
2016 | 3 | 4 | 7 |
2017 | 4 | 2 | 6 |
2018 | 4 | 1 | 5 |
2019 | 3 | 4 | 7 |
2020 | 2 | 3 | 5 |
2021 | 0 | 3 | 3 |
2022 | 3 | 0 | 3 |
2023 | 1 | 0 | 1 |
2024 | 1 | 2 | 3 |
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Below are the most recent publications written about "Telomerase" by people in Profiles.
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Clonal landscape and clinical outcomes of telomere biology disorders: somatic rescue and cancer mutations. Blood. 2024 Dec 05; 144(23):2402-2416.
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Analytical Validation of a Telomerase Reverse Transcriptase (TERT) Promoter Mutation Assay. J Clin Endocrinol Metab. 2024 Aug 13; 109(9):2269-2273.
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The DNA methylome of pediatric brain tumors appears shaped by structural variation and predicts survival. Nat Commun. 2024 Aug 08; 15(1):6775.
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TERT activation targets DNA methylation and multiple aging hallmarks. Cell. 2024 Jul 25; 187(15):4030-4042.e13.
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Determinants of mosaic chromosomal alteration fitness. Nat Commun. 2024 May 07; 15(1):3800.
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Noncanonical functions of telomerase and telomeres in viruses-associated cancer. J Med Virol. 2024 May; 96(5):e29665.
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Plasmacytoid urothelial carcinoma of the urinary bladder-A clinicopathological and molecular analysis of 52 cases. Hum Pathol. 2024 06; 148:1-6.
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Telomerase reverse transcriptase immunohistochemical expression is sensitive but not specific for TERT gene amplification in acral melanoma. J Cutan Pathol. 2023 Sep; 50(9):845-851.
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Hotspot of de novo telomere addition stabilizes linear amplicons in yeast grown in sulfate-limiting conditions. Genetics. 2023 05 26; 224(2).
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Hyperextended telomeres promote formation of C-circle DNA in telomerase positive human cells. J Biol Chem. 2023 05; 299(5):104665.