RNA-Directed DNA Polymerase
"RNA-Directed DNA Polymerase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that synthesizes DNA on an RNA template. It is encoded by the pol gene of retroviruses and by certain retrovirus-like elements. EC 2.7.7.49.
| Descriptor ID |
D012194
|
| MeSH Number(s) |
D08.811.913.696.445.308.300.750 D12.776.964.775.375.750 D12.776.964.970.600.850.375.750
|
| Concept/Terms |
RNA-Directed DNA Polymerase- RNA-Directed DNA Polymerase
- RNA Directed DNA Polymerase
- Reverse Transcriptase
- RNA Transcriptase
- DNA Polymerase, RNA-Directed
- DNA Polymerase, RNA Directed
- RNA-Dependent DNA Polymerase
- DNA Polymerase, RNA-Dependent
- RNA Dependent DNA Polymerase
- Revertase
|
Below are MeSH descriptors whose meaning is more general than "RNA-Directed DNA Polymerase".
Below are MeSH descriptors whose meaning is more specific than "RNA-Directed DNA Polymerase".
This graph shows the total number of publications written about "RNA-Directed DNA Polymerase" by people in this website by year, and whether "RNA-Directed DNA Polymerase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 4 | 6 |
| 1995 | 0 | 4 | 4 |
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 5 | 5 |
| 1998 | 2 | 2 | 4 |
| 1999 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2007 | 2 | 1 | 3 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "RNA-Directed DNA Polymerase" by people in Profiles.
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Association of mRNA Vaccination With Clinical and Virologic Features of COVID-19 Among US Essential and Frontline Workers. JAMA. 2022 10 18; 328(15):1523-1533.
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Pneumonia Frequency and Severity in Patients With Symptomatic COVID-19: Impact of mRNA and Adenovirus Vector Vaccines. AJR Am J Roentgenol. 2022 11; 219(5):752-761.
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Identification of protein-protected mRNA fragments and structured excised intron RNAs in human plasma by TGIRT-seq peak calling. Elife. 2020 09 02; 9.
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Template-switching mechanism of a group II intron-encoded reverse transcriptase and its implications for biological function and RNA-Seq. J Biol Chem. 2019 12 20; 294(51):19764-19784.
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Efficient pre-catalytic conformational change of reverse transcriptases from SAMHD1 non-counteracting primate lentiviruses during dNTP incorporation. Virology. 2019 11; 537:36-44.
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A Reverse Transcriptase-Cas1 Fusion Protein Contains a Cas6 Domain Required for Both CRISPR RNA Biogenesis and RNA Spacer Acquisition. Mol Cell. 2018 11 15; 72(4):700-714.e8.
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RNA-seq of human reference RNA samples using a thermostable group II intron reverse transcriptase. RNA. 2016 Apr; 22(4):597-613.
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A 3' Poly(A) Tract Is Required for LINE-1 Retrotransposition. Mol Cell. 2015 Dec 03; 60(5):728-741.
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High-throughput sequencing of human plasma RNA by using thermostable group II intron reverse transcriptases. RNA. 2016 Jan; 22(1):111-28.
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Cytotoxicity of human endogenous retrovirus K-specific T cells toward autologous ovarian cancer cells. Clin Cancer Res. 2015 Jan 15; 21(2):471-83.