RNA-Directed DNA Polymerase
"RNA-Directed DNA Polymerase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that synthesizes DNA on an RNA template. It is encoded by the pol gene of retroviruses and by certain retrovirus-like elements. EC 2.7.7.49.
| Descriptor ID |
D012194
|
| MeSH Number(s) |
D08.811.913.696.445.308.300.750 D12.776.964.775.375.750 D12.776.964.970.600.850.375.750
|
| Concept/Terms |
RNA-Directed DNA Polymerase- RNA-Directed DNA Polymerase
- RNA Directed DNA Polymerase
- Reverse Transcriptase
- RNA Transcriptase
- DNA Polymerase, RNA-Directed
- DNA Polymerase, RNA Directed
- RNA-Dependent DNA Polymerase
- DNA Polymerase, RNA-Dependent
- RNA Dependent DNA Polymerase
- Revertase
|
Below are MeSH descriptors whose meaning is more general than "RNA-Directed DNA Polymerase".
Below are MeSH descriptors whose meaning is more specific than "RNA-Directed DNA Polymerase".
This graph shows the total number of publications written about "RNA-Directed DNA Polymerase" by people in this website by year, and whether "RNA-Directed DNA Polymerase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 4 | 4 |
| 2001 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "RNA-Directed DNA Polymerase" by people in Profiles.
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Association of mRNA Vaccination With Clinical and Virologic Features of COVID-19 Among US Essential and Frontline Workers. JAMA. 2022 10 18; 328(15):1523-1533.
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Efficient pre-catalytic conformational change of reverse transcriptases from SAMHD1 non-counteracting primate lentiviruses during dNTP incorporation. Virology. 2019 11; 537:36-44.
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A 3' Poly(A) Tract Is Required for LINE-1 Retrotransposition. Mol Cell. 2015 Dec 03; 60(5):728-741.
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The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease. J Biol Chem. 2013 Jul 26; 288(30):21955-71.
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DTF1 is a core component of RNA-directed DNA methylation and may assist in the recruitment of Pol IV. Proc Natl Acad Sci U S A. 2013 May 14; 110(20):8290-5.
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Reverse transcriptase genotypes in pediatric patients failing initial antiretroviral therapy in Gaborone, Botswana. J Int Assoc Physicians AIDS Care (Chic). 2012 Jul-Aug; 11(4):260-8.
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Changes in simian immunodeficiency virus reverse transcriptase alleles that appear during infection of macaques enhance infectivity and replication in CD4+ T cells. Virology. 2008 Jan 05; 370(1):184-93.
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Mn2+ suppressor mutations and biochemical communication between Ty1 reverse transcriptase and RNase H domains. J Virol. 2007 Sep; 81(17):9004-12.
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Identification of a simian immunodeficiency virus reverse transcriptase variant with enhanced replicational fidelity in the late stage of viral infection. J Biol Chem. 2001 Jun 29; 276(26):23624-31.
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Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from the U6 promoter. J Natl Cancer Inst. 1998 Jul 15; 90(14):1080-7.