"DNA Polymerase III" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms but may be present in higher organisms. Use also for a more complex form of DNA polymerase III designated as DNA polymerase III* or pol III* which is 15 times more active biologically than DNA polymerase I in the synthesis of DNA. This polymerase has both 3'-5' and 5'-3' exonuclease activities, is inhibited by sulfhydryl reagents, and has the same template-primer dependence as pol II. EC 2.7.7.7.
| Descriptor ID |
D004258
|
| MeSH Number(s) |
D08.811.913.696.445.308.300.235
|
| Concept/Terms |
DNA Polymerase III- DNA Polymerase III
- Polymerase III, DNA
- DNA Pol III
- DNA Polymerase delta
- Polymerase delta, DNA
- DNA-Dependent DNA Polymerase III
- DNA Dependent DNA Polymerase III
|
Below are MeSH descriptors whose meaning is more general than "DNA Polymerase III".
Below are MeSH descriptors whose meaning is more specific than "DNA Polymerase III".
This graph shows the total number of publications written about "DNA Polymerase III" by people in this website by year, and whether "DNA Polymerase III" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2019 | 0 | 1 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Polymerase III" by people in Profiles.
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Endogenous DNA damage at sites of terminated transcripts. Nature. 2025 Apr; 640(8057):240-248.
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CRISPR/CAS9-based DNA damage response screens reveal gene-drug interactions. DNA Repair (Amst). 2020 03; 87:102803.
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Nuclear receptors regulate alternative lengthening of telomeres through a novel noncanonical FANCD2 pathway. Sci Adv. 2019 10; 5(10):eaax6366.
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Role of the Pif1-PCNA Complex in Pol d-Dependent Strand Displacement DNA Synthesis and Break-Induced Replication. Cell Rep. 2017 Nov 14; 21(7):1707-1714.
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MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells. Nat Commun. 2017 10 16; 8(1):860.
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The DNA polymerase III holoenzyme contains ? and is not a trimeric polymerase. Nucleic Acids Res. 2016 Feb 18; 44(3):1285-97.
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The sliding clamp tethers the endonuclease domain of MutL to DNA. Nucleic Acids Res. 2015 Dec 15; 43(22):10746-59.
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Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication. Genome Res. 2014 Nov; 24(11):1740-50.
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Pif1 helicase and Pold promote recombination-coupled DNA synthesis via bubble migration. Nature. 2013 Oct 17; 502(7471):393-6.
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Proliferating cell nuclear antigen (PCNA)-binding protein C1orf124 is a regulator of translesion synthesis. J Biol Chem. 2012 Oct 05; 287(41):34225-33.