"Gene Products, pol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Retroviral proteins coded by the pol gene. They are usually synthesized as a protein precursor (POLYPROTEINS) and later cleaved into final products that include reverse transcriptase, endonuclease/integrase, and viral protease. Sometimes they are synthesized as a gag-pol fusion protein (FUSION PROTEINS, GAG-POL). pol is short for polymerase, the enzyme class of reverse transcriptase.
| Descriptor ID |
D015684
|
| MeSH Number(s) |
D12.776.775.360 D12.776.964.775.375 D12.776.964.970.600.850.375
|
| Concept/Terms |
Gene Products, pol- Gene Products, pol
- pol Gene Products
- pol Protein
- Protein, pol
- pol Polyprotein
- Polyprotein, pol
- pol Polyproteins
- Polyproteins, pol
- Gene Product, pol
- pol Gene Product
|
Below are MeSH descriptors whose meaning is more general than "Gene Products, pol".
Below are MeSH descriptors whose meaning is more specific than "Gene Products, pol".
This graph shows the total number of publications written about "Gene Products, pol" by people in this website by year, and whether "Gene Products, pol" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Gene Products, pol" by people in Profiles.
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Qki activates Srebp2-mediated cholesterol biosynthesis for maintenance of eye lens transparency. Nat Commun. 2021 05 21; 12(1):3005.
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Activation drives PD-1 expression during vaccine-specific proliferation and following lentiviral infection in macaques. Eur J Immunol. 2008 May; 38(5):1435-45.
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Design, construction, and characterization of a dual-promoter multigenic DNA vaccine directed against an HIV-1 subtype C/B' recombinant. J Acquir Immune Defic Syndr. 2008 Apr 01; 47(4):403-11.
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Design, construction, and characterization of a multigenic modified vaccinia Ankara candidate vaccine against human immunodeficiency virus type 1 subtype C/B'. J Acquir Immune Defic Syndr. 2008 Apr 01; 47(4):412-21.
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Immunogenicity and protective efficacy of Gag/Pol/Env vaccines derived from temporal isolates of SIVmne against cognate virus challenge. J Med Primatol. 2007 Aug; 36(4-5):254-65.
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Association of hepatitis B virus polymerase with promyelocytic leukemia nuclear bodies mediated by the S100 family protein p11. Biochem Biophys Res Commun. 2003 Jun 13; 305(4):1049-56.
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Glomerulosclerosis and viral gene expression in HIV-transgenic mice: role of nef. Kidney Int. 2000 Sep; 58(3):1148-59.
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Analysis of human immunodeficiency virus type 1 integrase mutants. Virology. 1995 Aug 01; 211(1):332-5.
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Isolation of a type D retrovirus from B-cell lymphomas of a patient with AIDS. J Virol. 1991 Nov; 65(11):5663-72.