"Histones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc.) is based on the relative amounts of arginine and lysine in each.
| Descriptor ID |
D006657
|
| MeSH Number(s) |
D12.776.157.687.485 D12.776.660.720.485 D12.776.664.469
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Histones".
Below are MeSH descriptors whose meaning is more specific than "Histones".
This graph shows the total number of publications written about "Histones" by people in this website by year, and whether "Histones" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 1 | 3 | 4 |
| 2003 | 4 | 4 | 8 |
| 2004 | 2 | 1 | 3 |
| 2005 | 2 | 3 | 5 |
| 2006 | 4 | 5 | 9 |
| 2007 | 1 | 2 | 3 |
| 2008 | 4 | 4 | 8 |
| 2009 | 6 | 10 | 16 |
| 2010 | 4 | 9 | 13 |
| 2011 | 7 | 8 | 15 |
| 2012 | 7 | 10 | 17 |
| 2013 | 6 | 13 | 19 |
| 2014 | 7 | 15 | 22 |
| 2015 | 8 | 19 | 27 |
| 2016 | 9 | 14 | 23 |
| 2017 | 5 | 16 | 21 |
| 2018 | 10 | 7 | 17 |
| 2019 | 8 | 15 | 23 |
| 2020 | 6 | 14 | 20 |
| 2021 | 7 | 13 | 20 |
| 2022 | 7 | 4 | 11 |
| 2023 | 8 | 6 | 14 |
| 2024 | 9 | 3 | 12 |
| 2025 | 4 | 6 | 10 |
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Below are the most recent publications written about "Histones" by people in Profiles.
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Bromodomain-Driven Regulation of Stem Cells: A Potential Target for Cancer Therapeutic Intervention. Stem Cell Rev Rep. 2026 Feb; 22(2):767-802.
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EZHIP boosts neuronal-like synaptic gene programs and depresses polyamine metabolism. Acta Neuropathol Commun. 2025 Nov 07; 13(1):227.
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ADNP Exhibits Methyltransferase Activity in Overexpression Systems and Modulates DNA and Histone Methylation. Autism Res. 2025 Nov; 18(11):2174-2191.
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Assessment of the histone mark-based epigenomic landscape in human myometrium at term pregnancy. Elife. 2025 Jun 10; 13.
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Let-7 restrains an epigenetic circuit in AT2 cells to prevent fibrogenic intermediates in pulmonary fibrosis. Nat Commun. 2025 May 10; 16(1):4353.
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Histone acetylation modulators in breast cancer. Breast Cancer Res. 2025 Mar 31; 27(1):49.
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Normalized and Directional Interplay Scoring for the Interrogation of Proteoform Data. J Proteome Res. 2025 Apr 04; 24(4):1765-1777.
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Modulation of Stemness and Differentiation Regulators by Valproic Acid in Medulloblastoma Neurospheres. Cells. 2025 01 07; 14(2).
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Monoallelic expression can govern penetrance of inborn errors of immunity. Nature. 2025 Jan; 637(8048):1186-1197.
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High-Throughput Post-Translational Modification Analyses by Reverse Phase Protein Array. Methods Mol Biol. 2025; 2929:53-69.