"Histones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc.) is based on the relative amounts of arginine and lysine in each.
| Descriptor ID |
D006657
|
| MeSH Number(s) |
D12.776.157.687.485 D12.776.660.720.485 D12.776.664.469
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Histones".
Below are MeSH descriptors whose meaning is more specific than "Histones".
This graph shows the total number of publications written about "Histones" by people in this website by year, and whether "Histones" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 1 | 3 | 4 |
| 2003 | 4 | 4 | 8 |
| 2004 | 2 | 1 | 3 |
| 2005 | 2 | 3 | 5 |
| 2006 | 4 | 5 | 9 |
| 2007 | 1 | 2 | 3 |
| 2008 | 4 | 4 | 8 |
| 2009 | 6 | 10 | 16 |
| 2010 | 4 | 9 | 13 |
| 2011 | 7 | 8 | 15 |
| 2012 | 7 | 10 | 17 |
| 2013 | 7 | 14 | 21 |
| 2014 | 7 | 16 | 23 |
| 2015 | 8 | 19 | 27 |
| 2016 | 9 | 14 | 23 |
| 2017 | 5 | 16 | 21 |
| 2018 | 10 | 6 | 16 |
| 2019 | 8 | 15 | 23 |
| 2020 | 6 | 14 | 20 |
| 2021 | 7 | 13 | 20 |
| 2022 | 7 | 4 | 11 |
| 2023 | 8 | 6 | 14 |
| 2024 | 11 | 3 | 14 |
| 2025 | 7 | 9 | 16 |
| 2026 | 0 | 2 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Histones" by people in Profiles.
-
CHK1 is an integral regulator of DNA replication in human cells. Cell Death Dis. 2026 Mar 26; 17(1).
-
A side-by-side comparison of commercial CUT&RUN kits. J Biomol Tech. 2026; 37(1):4-17.
-
Rare epigenetic alterations are conserved across hematopoietic differentiation stages after mycobacterial infection. JCI Insight. 2026 Jan 23; 11(2).
-
Bromodomain-Driven Regulation of Stem Cells: A Potential Target for Cancer Therapeutic Intervention. Stem Cell Rev Rep. 2026 Feb; 22(2):767-802.
-
EZHIP boosts neuronal-like synaptic gene programs and depresses polyamine metabolism. Acta Neuropathol Commun. 2025 Nov 07; 13(1):227.
-
ADNP Exhibits Methyltransferase Activity in Overexpression Systems and Modulates DNA and Histone Methylation. Autism Res. 2025 Nov; 18(11):2174-2191.
-
A needed nomenclature for nucleosomes. Mol Cell. 2025 Oct 02; 85(19):3554-3561.
-
Lysosomes signal through the epigenome to regulate longevity across generations. Science. 2025 Sep 25; 389(6767):1353-1360.
-
Assessment of the histone mark-based epigenomic landscape in human myometrium at term pregnancy. Elife. 2025 Jun 10; 13.
-
Let-7 restrains an epigenetic circuit in AT2 cells to prevent fibrogenic intermediates in pulmonary fibrosis. Nat Commun. 2025 May 10; 16(1):4353.