"Histones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc.) is based on the relative amounts of arginine and lysine in each.
| Descriptor ID |
D006657
|
| MeSH Number(s) |
D12.776.157.687.485 D12.776.660.720.485 D12.776.664.469
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Histones".
Below are MeSH descriptors whose meaning is more specific than "Histones".
This graph shows the total number of publications written about "Histones" by people in this website by year, and whether "Histones" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 1 | 2 |
| 1998 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 3 | 3 |
| 2002 | 1 | 2 | 3 |
| 2003 | 5 | 3 | 8 |
| 2004 | 2 | 1 | 3 |
| 2005 | 3 | 3 | 6 |
| 2006 | 4 | 7 | 11 |
| 2007 | 0 | 4 | 4 |
| 2008 | 4 | 5 | 9 |
| 2009 | 6 | 12 | 18 |
| 2010 | 4 | 10 | 14 |
| 2011 | 7 | 9 | 16 |
| 2012 | 7 | 10 | 17 |
| 2013 | 8 | 15 | 23 |
| 2014 | 6 | 14 | 20 |
| 2015 | 8 | 16 | 24 |
| 2016 | 9 | 13 | 22 |
| 2017 | 5 | 12 | 17 |
| 2018 | 10 | 8 | 18 |
| 2019 | 8 | 15 | 23 |
| 2020 | 6 | 16 | 22 |
| 2021 | 7 | 13 | 20 |
| 2022 | 6 | 3 | 9 |
| 2023 | 6 | 4 | 10 |
| 2024 | 10 | 3 | 13 |
| 2025 | 3 | 3 | 6 |
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Below are the most recent publications written about "Histones" by people in Profiles.
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Let-7 restrains an epigenetic circuit in AT2 cells to prevent fibrogenic intermediates in pulmonary fibrosis. Nat Commun. 2025 May 10; 16(1):4353.
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Histone H3 cysteine 110 enhances iron metabolism and modulates replicative life span in Saccharomyces cerevisiae. Sci Adv. 2025 Apr 11; 11(15):eadv4082.
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Histone acetylation modulators in breast cancer. Breast Cancer Res. 2025 Mar 31; 27(1):49.
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Normalized and Directional Interplay Scoring for the Interrogation of Proteoform Data. J Proteome Res. 2025 Apr 04; 24(4):1765-1777.
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Conformational switching of Arp5 subunit regulates INO80 chromatin remodeling. Nucleic Acids Res. 2025 Jan 11; 53(2).
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Placentas From SARS-CoV-2 Infection During Pregnancy Exhibit Foci of Oxidative Stress and DNA Damage. Am J Reprod Immunol. 2025 Jan; 93(1):e70034.
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Monoallelic expression can govern penetrance of inborn errors of immunity. Nature. 2025 Jan; 637(8048):1186-1197.
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Acute MeCP2 loss in adult mice reveals transcriptional and chromatin changes that precede neurological dysfunction and inform pathogenesis. Neuron. 2025 Feb 05; 113(3):380-395.e8.
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Interplay of Reactive Oxygen Species (ROS) and Epigenetic Remodelling in Cardiovascular Diseases Pathogenesis: A Contemporary Perspective. Front Biosci (Landmark Ed). 2024 Nov 21; 29(11):398.
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Nuclear PD-L1 compartmentalization suppresses tumorigenesis and overcomes immunocheckpoint therapy resistance in mice via histone macroH2A1. J Clin Invest. 2024 Nov 15; 134(22).