CCAAT-Enhancer-Binding Proteins
"CCAAT-Enhancer-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of proteins that were originally identified by their ability to bind the DNA sequence CCAAT. The typical CCAAT-enhancer binding protein forms dimers and consists of an activation domain, a DNA-binding basic region, and a leucine-rich dimerization domain (LEUCINE ZIPPERS). CCAAT-BINDING FACTOR is structurally distinct type of CCAAT-enhancer binding protein consisting of a trimer of three different subunits.
| Descriptor ID |
D022762
|
| MeSH Number(s) |
D12.776.260.108.124 D12.776.660.167 D12.776.930.127.124
|
| Concept/Terms |
CCAAT-Enhancer-Binding Proteins- CCAAT-Enhancer-Binding Proteins
- CCAAT Enhancer Binding Proteins
- CAAT-Enhancer Binding Protein
- Binding Protein, CAAT-Enhancer
- CAAT Enhancer Binding Protein
- CCAAT-Enhancer-Binding Protein
- CCAAT Enhancer Binding Protein
- C-EBP Protein
- C EBP Protein
- C-EBP Nuclear Protein
- C EBP Nuclear Protein
- Nuclear Protein, C-EBP
- CAAT-Enhancer-Binding Proteins
- CAAT Enhancer Binding Proteins
- C-EBP Proteins
- C EBP Proteins
- CCAAT Sequence-Specific DNA-Binding Proteins
- CCAAT Sequence Specific DNA Binding Proteins
- Nuclear Protein C-EBP
- C-EBP, Nuclear Protein
- Nuclear Protein C EBP
|
Below are MeSH descriptors whose meaning is more general than "CCAAT-Enhancer-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "CCAAT-Enhancer-Binding Proteins".
This graph shows the total number of publications written about "CCAAT-Enhancer-Binding Proteins" by people in this website by year, and whether "CCAAT-Enhancer-Binding Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 5 | 5 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 4 | 5 |
| 2002 | 1 | 2 | 3 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2014 | 0 | 3 | 3 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2021 | 1 | 2 | 3 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "CCAAT-Enhancer-Binding Proteins" by people in Profiles.
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TR? activation confers AT2-to-AT1 cell differentiation and anti-fibrosis during lung repair via KLF2 and CEBPA. Nat Commun. 2024 Oct 07; 15(1):8672.
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Insight into the mechanism of AML del(9q) progression: hnRNP K targets the myeloid master regulators CEBPA (C/EBPa) and SPI1 (PU.1). Biochim Biophys Acta Gene Regul Mech. 2024 Mar; 1867(1):195004.
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Dynamics of alternative splicing during somatic cell reprogramming reveals functions for RNA-binding proteins CPSF3, hnRNP UL1, and TIA1. Genome Biol. 2021 06 03; 22(1):171.
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Preferential CEBP binding to T:G mismatches and increased C-to-T human somatic mutations. Nucleic Acids Res. 2021 05 21; 49(9):5084-5094.
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Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia. Nat Commun. 2021 05 10; 12(1):2607.
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Converging genetic and epigenetic drivers of paediatric acute lymphoblastic leukaemia identified by an information-theoretic analysis. Nat Biomed Eng. 2021 04; 5(4):360-376.
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Discovery of small molecules targeting the tandem tudor domain of the epigenetic factor UHRF1 using fragment-based ligand discovery. Sci Rep. 2021 01 13; 11(1):1121.
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The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cells. Epigenetics Chromatin. 2020 10 23; 13(1):44.
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Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a. Nat Commun. 2018 07 03; 9(1):2583.
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NR4A1 and NR4A3 restrict HSC proliferation via reciprocal regulation of C/EBPa and inflammatory signaling. Blood. 2018 03 08; 131(10):1081-1093.