"CCAAT-Binding Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterotrimeric DNA-binding protein that binds to CCAAT motifs in the promoters of eukaryotic genes. It is composed of three subunits: A, B and C.
| Descriptor ID |
D023081
|
| MeSH Number(s) |
D12.776.260.108.124.249 D12.776.660.167.249 D12.776.930.127.124.249
|
| Concept/Terms |
CCAAT-Binding Factor- CCAAT-Binding Factor
- CCAAT Binding Factor
- CCAAT-Binding-Factor
- CCAAT-Binding Transcription Factor
- CCAAT Binding Transcription Factor
- Transcription Factor, CCAAT-Binding
- NF-Y Protein
- NF Y Protein
- Protein, NF-Y
- CBF Protein, CCAAT-Binding
- CBF Protein, CCAAT Binding
- CCAAT-Binding CBF Protein
- CCAAT-Binding Protein, CP1
- CCAAT Binding Protein, CP1
- CP1 CCAAT-Binding Protein
CCAAT-Binding Factor, B-Subunit- CCAAT-Binding Factor, B-Subunit
- CCAAT Binding Factor, B Subunit
- Factor, B-Subunit CCAAT-Binding
- CBF-B Protein, CCAAT-Binding
- CBF B Protein, CCAAT Binding
- CCAAT-Binding CBF-B Protein
- Protein, CCAAT-Binding CBF-B
CCAAT-Binding Factor, C-Subunit- CCAAT-Binding Factor, C-Subunit
- CCAAT Binding Factor, C Subunit
- Factor, C-Subunit CCAAT-Binding
- CBF-C Protein, CCAAT-Binding
- CBF C Protein, CCAAT Binding
- CCAAT-Binding CBF-C Protein
CCAAT-Binding Factor, A-Subunit- CCAAT-Binding Factor, A-Subunit
- CCAAT Binding Factor, A Subunit
- Factor, A-Subunit CCAAT-Binding
- CBF-A Protein, CCAAT-Binding
- CBF A Protein, CCAAT Binding
- CCAAT-Binding CBF-A Protein
- Protein, CCAAT-Binding CBF-A
|
Below are MeSH descriptors whose meaning is more general than "CCAAT-Binding Factor".
Below are MeSH descriptors whose meaning is more specific than "CCAAT-Binding Factor".
This graph shows the total number of publications written about "CCAAT-Binding Factor" by people in this website by year, and whether "CCAAT-Binding Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 2 | 1 | 3 |
| 2003 | 2 | 0 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 2 | 3 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 3 | 0 | 3 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "CCAAT-Binding Factor" by people in Profiles.
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The transcription factor NF-YA is crucial for neural progenitor maintenance during brain development. J Biol Chem. 2024 Feb; 300(2):105629.
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Gene expression profiling in neuronal cells identifies a different type of transcriptome modulated by NF-Y. Sci Rep. 2020 12 10; 10(1):21714.
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CCAAT-displacement protein/cut homeobox transcription factor (CUX1) represses estrogen receptor-alpha (ER-a) in triple-negative breast cancer cells and can be antagonized by muscadine grape skin extract (MSKE). PLoS One. 2019; 14(4):e0214844.
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NF-Y (CBF) regulation in specific cell types and mouse models. Biochim Biophys Acta Gene Regul Mech. 2017 May; 1860(5):598-603.
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Context-specific role of SOX9 in NF-Y mediated gene regulation in colorectal cancer cells. Nucleic Acids Res. 2015 Jul 27; 43(13):6257-69.
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NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization. Nat Commun. 2014 Feb 25; 5:3354.
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Inactivation of CBF/NF-Y in postnatal liver causes hepatocellular degeneration, lipid deposition, and endoplasmic reticulum stress. Sci Rep. 2011; 1:136.
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TopBP1 mediates mutant p53 gain of function through NF-Y and p63/p73. Mol Cell Biol. 2011 Nov; 31(22):4464-81.
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Resveratrol, through NF-Y/p53/Sin3/HDAC1 complex phosphorylation, inhibits estrogen receptor alpha gene expression via p38MAPK/CK2 signaling in human breast cancer cells. FASEB J. 2011 Oct; 25(10):3695-707.
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Long-range function of an intergenic retrotransposon. Proc Natl Acad Sci U S A. 2010 Jul 20; 107(29):12992-7.