"Y-Box-Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CCAAT-enhancer-binding protein that was originally identified as interacting with Y-box PROMOTER REGIONS of MHC CLASS II GENES. It is a highly conserved transcription factor that regulates expression of a wide variety of GENES.
| Descriptor ID |
D051840
|
| MeSH Number(s) |
D12.776.260.108.124.937 D12.776.660.167.937 D12.776.930.127.124.937
|
| Concept/Terms |
Y-Box-Binding Protein 1- Y-Box-Binding Protein 1
- Y Box Binding Protein 1
- Y-Box Protein-1
- Y Box Protein 1
- NSEP1 Transcription Factor
- Transcription Factor, NSEP1
- Y-Box Binding Protein YB-1
- Y Box Binding Protein YB 1
- Nuclease Sensitive Element Binding Protein 1
- DNA Binding Protein B
|
Below are MeSH descriptors whose meaning is more general than "Y-Box-Binding Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Y-Box-Binding Protein 1".
This graph shows the total number of publications written about "Y-Box-Binding Protein 1" by people in this website by year, and whether "Y-Box-Binding Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 2 | 0 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Y-Box-Binding Protein 1" by people in Profiles.
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Behavioral screening reveals a conserved residue in Y-Box RNA-binding protein required for associative learning and memory in C. elegans. PLoS Genet. 2024 Oct; 20(10):e1011443.
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Multiomics analyses reveal DARS1-AS1/YBX1-controlled posttranscriptional circuits promoting glioblastoma tumorigenesis/radioresistance. Sci Adv. 2023 08 04; 9(31):eadf3984.
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YBX1 is required for maintaining myeloid leukemia cell survival by regulating BCL2 stability in an m6A-dependent manner. Blood. 2021 07 08; 138(1):71-85.
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The long noncoding RNA AATBC promotes breast cancer migration and invasion by interacting with YBX1 and activating the YAP1/Hippo signaling pathway. Cancer Lett. 2021 08 01; 512:60-72.
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ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma. Cancer Cell. 2017 07 10; 32(1):88-100.e6.
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The role of Interleukin Receptor Associated Kinase (IRAK)-M in regulation of myofibroblast phenotype in vitro, and in an experimental model of non-reperfused myocardial infarction. J Mol Cell Cardiol. 2015 Dec; 89(Pt B):223-31.
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YB-1 transforms human mammary epithelial cells through chromatin remodeling leading to the development of basal-like breast cancer. Stem Cells. 2014 Jun; 32(6):1437-50.
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Role of focal adhesion kinase in regulating YB-1-mediated paclitaxel resistance in ovarian cancer. J Natl Cancer Inst. 2013 Oct 02; 105(19):1485-95.
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Self-reinforcing loop of amphiregulin and Y-box binding protein-1 contributes to poor outcomes in ovarian cancer. Oncogene. 2014 May 29; 33(22):2846-56.
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MKNK1 is a YB-1 target gene responsible for imparting trastuzumab resistance and can be blocked by RSK inhibition. Oncogene. 2012 Oct 11; 31(41):4434-46.