"Syndecan-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A syndecan that is predominantly expressed during EMBRYONIC DEVELOPMENT. It may play a role in mediating cellular interactions with the EXTRACELLULAR MATRIX and may modulate the signaling activity of certain INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS.
| Descriptor ID |
D053669
|
| MeSH Number(s) |
D12.776.395.550.847.200 D12.776.395.650.350.500.200 D12.776.543.550.847.200
|
| Concept/Terms |
Syndecan-2- Syndecan-2
- Syndecan 2
- Fibroglycan
- Heparan Sulfate Proteoglycan Core Protein
|
Below are MeSH descriptors whose meaning is more general than "Syndecan-2".
Below are MeSH descriptors whose meaning is more specific than "Syndecan-2".
This graph shows the total number of publications written about "Syndecan-2" by people in this website by year, and whether "Syndecan-2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Syndecan-2" by people in Profiles.
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Syndecan-2 regulates PAD2 to exert antifibrotic effects on RA-ILD fibroblasts. Sci Rep. 2022 02 18; 12(1):2847.
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Mesenchymal stromal cell-derived syndecan-2 regulates the immune response during sepsis to foster bacterial clearance and resolution of inflammation. FEBS J. 2022 01; 289(2):417-435.
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CD148 Deficiency in Fibroblasts Promotes the Development of Pulmonary Fibrosis. Am J Respir Crit Care Med. 2021 08 01; 204(3):312-325.
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Lung Adenocarcinoma Syndecan-2 Potentiates Cell Invasiveness. Am J Respir Cell Mol Biol. 2019 06; 60(6):659-666.
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Syndecan-2 Attenuates Radiation-induced Pulmonary Fibrosis and Inhibits Fibroblast Activation by Regulating PI3K/Akt/ROCK Pathway via CD148. Am J Respir Cell Mol Biol. 2018 02; 58(2):208-215.
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PKM2 regulates neural invasion of and predicts poor prognosis for human hilar cholangiocarcinoma. Mol Cancer. 2015 Nov 14; 14:193.
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Syndecan-2 exerts antifibrotic effects by promoting caveolin-1-mediated transforming growth factor-? receptor I internalization and inhibiting transforming growth factor-?1 signaling. Am J Respir Crit Care Med. 2013 Oct 01; 188(7):831-41.