Heparan Sulfate Proteoglycans
"Heparan Sulfate Proteoglycans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ubiquitous macromolecules associated with the cell surface and extracellular matrix of a wide range of cells of vertebrate and invertebrate tissues. They are essential cofactors in cell-matrix adhesion processes, in cell-cell recognition systems, and in receptor-growth factor interactions. (From Cancer Metastasis Rev 1996; 15(2): 177-86; Hepatology 1996; 24(3): 524-32)
Descriptor ID |
D019812
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MeSH Number(s) |
D09.698.373.425.500 D09.698.735.400 D12.776.395.650.350
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Concept/Terms |
Heparan Sulfate Proteoglycans- Heparan Sulfate Proteoglycans
- Proteoglycans, Heparan Sulfate
- Sulfate Proteoglycans, Heparan
- HSPG
- Proteoheparan Sulfate
- Heparan Sulfate Proteoglycan
- Proteoglycan, Heparan Sulfate
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Below are MeSH descriptors whose meaning is more general than "Heparan Sulfate Proteoglycans".
Below are MeSH descriptors whose meaning is more specific than "Heparan Sulfate Proteoglycans".
This graph shows the total number of publications written about "Heparan Sulfate Proteoglycans" by people in this website by year, and whether "Heparan Sulfate Proteoglycans" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 0 | 1 | 1 |
2020 | 1 | 0 | 1 |
2021 | 1 | 0 | 1 |
2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Heparan Sulfate Proteoglycans" by people in Profiles.
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The interaction of endorepellin and neurexin triggers neuroepithelial autophagy and maintains neural tube development. Sci Bull (Beijing). 2024 Jul 30; 69(14):2260-2272.
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Targeting of Mammalian Glycans Enhances Phage Predation in the Gastrointestinal Tract. mBio. 2021 02 09; 12(1).
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Enteroaggregative E. coli Adherence to Human Heparan Sulfate Proteoglycans Drives Segment and Host Specific Responses to Infection. PLoS Pathog. 2020 09; 16(9):e1008851.
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SULF1 suppresses Wnt3A-driven growth of bone metastatic prostate cancer in perlecan-modified 3D cancer-stroma-macrophage triculture models. PLoS One. 2020; 15(5):e0230354.
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Extracellular matrix-derived peptides in tissue remodeling and fibrosis. Matrix Biol. 2020 09; 91-92:176-187.
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Perlecan domain I gradients establish stable biomimetic heparin binding growth factor gradients for cell migration in hydrogels. Acta Biomater. 2019 10 01; 97:385-398.
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A Gastric Glycoform of MUC5AC Is a Biomarker of Mucinous Cysts of the Pancreas. PLoS One. 2016; 11(12):e0167070.
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Loss of SPARC dysregulates basal lamina assembly to disrupt larval fat body homeostasis in Drosophila melanogaster. Dev Dyn. 2015 Apr; 244(4):540-52.
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Transcriptional activation by NF?B increases perlecan/HSPG2 expression in the desmoplastic prostate tumor microenvironment. J Cell Biochem. 2014 Jul; 115(7):1322-33.
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Perlecan-containing pericellular matrix regulates solute transport and mechanosensing within the osteocyte lacunar-canalicular system. J Bone Miner Res. 2014 Apr; 29(4):878-91.