"Syndecans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of transmembrane glycoproteins that contain a short cytoplasmic domain, a single-span transmembrane domain, and an extracellular domain with heparin sulfate and CHONDROITIN SULFATE chains. Syndecans interact with a variety of heparin-binding INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS and may play a role in modulating cellular signaling during EMBRYONIC DEVELOPMENT, tumorigenesis, and angiogenesis.
| Descriptor ID |
D053667
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| MeSH Number(s) |
D12.776.395.550.847 D12.776.395.650.350.500 D12.776.543.550.847
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Syndecans".
Below are MeSH descriptors whose meaning is more specific than "Syndecans".
This graph shows the total number of publications written about "Syndecans" by people in this website by year, and whether "Syndecans" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 4 | 4 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Syndecans" by people in Profiles.
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Multifunctionalization of Cells with a Self-Assembling Molecule to Enhance Cell Engraftment. ACS Chem Biol. 2019 04 19; 14(4):775-783.
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Small-molecule-induced clustering of heparan sulfate promotes cell adhesion. J Am Chem Soc. 2013 Jul 31; 135(30):11032-9.
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Interstitial guidance of cancer invasion. J Pathol. 2012 Jan; 226(2):185-99.
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Modulation of GEF-H1 induced signaling by heparanase in brain metastatic melanoma cells. J Cell Biochem. 2010 Dec 01; 111(5):1299-309.
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Interstitial cell migration: integrin-dependent and alternative adhesion mechanisms. Cell Tissue Res. 2010 Jan; 339(1):83-92.
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Transmembrane domains of the syndecan family of growth factor coreceptors display a hierarchy of homotypic and heterotypic interactions. Proc Natl Acad Sci U S A. 2007 Dec 26; 104(52):20782-7.
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Primary plasma cell leukemia: morphologic, immunophenotypic, and cytogenetic features of 4 cases treated with chemotherapy and stem cell transplantation. Ann Diagn Pathol. 2006 Oct; 10(5):263-8.
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The molecular classification of multiple myeloma. Blood. 2006 Sep 15; 108(6):2020-8.
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Endogenous attenuation of allergic lung inflammation by syndecan-1. J Immunol. 2005 May 01; 174(9):5758-65.
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Regulated expression of ADAMTS family members in follicles and cumulus oocyte complexes: evidence for specific and redundant patterns during ovulation. Biol Reprod. 2005 May; 72(5):1241-55.