"Glypicans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of GLYCOSYLPHOSPHATIDYLINOSITOL-anchored, cell-surface heparan sulfate proteoglycans that may play a role in CELL GROWTH PROCESSES and CELL DIFFERENTIATION by modulating ligand-receptor interactions.
| Descriptor ID |
D053673
|
| MeSH Number(s) |
D12.776.395.550.448.500 D12.776.395.650.350.249 D12.776.543.484.500.550 D12.776.543.550.418.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Glypicans".
Below are MeSH descriptors whose meaning is more specific than "Glypicans".
This graph shows the total number of publications written about "Glypicans" by people in this website by year, and whether "Glypicans" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 3 | 0 | 3 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 2 | 3 |
| 2021 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Glypicans" by people in Profiles.
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Integrated Imaging Probe and Bispecific Antibody Development Enables In Vivo Targeting of Glypican-3-Expressing Hepatocellular Carcinoma. Mol Cancer Ther. 2024 Dec 03; 23(12):1815-1826.
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Interleukin-15-armoured GPC3 CAR T cells for patients with solid cancers. Nature. 2025 Jan; 637(8047):940-946.
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Targeting Lin28 axis enhances glypican-3-CAR T?cell efficacy against hepatic tumor initiating cell population. Mol Ther. 2023 03 01; 31(3):715-728.
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Novel low-avidity glypican-3 specific CARTs resist exhaustion and mediate durable antitumor effects against HCC. Hepatology. 2022 08; 76(2):330-344.
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Characterization of the Robinow syndrome skeletal phenotype, bone micro-architecture, and genotype-phenotype correlations with the osteosclerotic form. Am J Med Genet A. 2020 11; 182(11):2632-2640.
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Chimeric Antigen Receptor-Glypican-3 T-Cell Therapy for Advanced Hepatocellular Carcinoma: Results of Phase I Trials. Clin Cancer Res. 2020 08 01; 26(15):3979-3989.
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PIK3CA variants selectively initiate brain hyperactivity during gliomagenesis. Nature. 2020 02; 578(7793):166-171.
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Glypican-3-Specific CAR T Cells Coexpressing IL15 and IL21 Have Superior Expansion and Antitumor Activity against Hepatocellular Carcinoma. Cancer Immunol Res. 2020 03; 8(3):309-320.
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Ectopic Fetal Hepatic Tissue in the Placenta. Int J Gynecol Pathol. 2019 Sep; 38(5):426-429.
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Pathogenic Variants in GPC4 Cause Keipert Syndrome. Am J Hum Genet. 2019 05 02; 104(5):914-924.