"Ephrin-A1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ephrin that was originally identified as the product of an early response gene induced by TUMOR NECROSIS FACTORS. It is linked to the CELL MEMBRANE via a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR and binds EPHA2 RECEPTOR with high affinity. During embryogenesis high levels of ephrin-A1 are expressed in LUNG; KIDNEY; SALIVARY GLANDS; and INTESTINE.
| Descriptor ID |
D036382
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| MeSH Number(s) |
D12.644.276.500.100 D12.776.395.550.448.300 D12.776.467.500.100 D12.776.543.287.100 D12.776.543.484.500.300 D12.776.543.550.418.300 D23.529.500.100
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| Concept/Terms |
Ephrin-A1- Ephrin-A1
- Ephrin A1
- Eck Ligand
- Ligand, Eck
- LERK-1 Protein
- LERK 1 Protein
- Endothelium Secreted Protein B61
- Epl1 Protein
- EPLG1
- B61 Secreted Protein, Endothelium
- Eck RPTK Ligand
- RPTK Ligand, Eck
|
Below are MeSH descriptors whose meaning is more general than "Ephrin-A1".
Below are MeSH descriptors whose meaning is more specific than "Ephrin-A1".
This graph shows the total number of publications written about "Ephrin-A1" by people in this website by year, and whether "Ephrin-A1" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ephrin-A1" by people in Profiles.
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The effect of ephrin-A1 on resistance to Photofrin-mediated photodynamic therapy in esophageal squamous cell carcinoma cells. Lasers Med Sci. 2015 Dec; 30(9):2353-61.
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The EphA2 receptor drives self-renewal and tumorigenicity in stem-like tumor-propagating cells from human glioblastomas. Cancer Cell. 2012 Dec 11; 22(6):765-80.
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Biomimetic hydrogels with immobilized ephrinA1 for therapeutic angiogenesis. Biomacromolecules. 2011 Jul 11; 12(7):2715-22.
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Expression and prognostic significance of a panel of tissue hypoxia markers in head-and-neck squamous cell carcinomas. Int J Radiat Oncol Biol Phys. 2007 Sep 01; 69(1):167-75.
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The genes encoding the eph-related receptor tyrosine kinase ligands LERK-1 (EPLG1, Epl1), LERK-3 (EPLG3, Epl3), and LERK-4 (EPLG4, Epl4) are clustered on human chromosome 1 and mouse chromosome 3. Genomics. 1996 Apr 15; 33(2):277-82.