"GPI-Linked Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of lipid-linked proteins that contain a GLYCOSYLPHOSPHATIDYLINOSITOL LINKAGE which holds them to the CELL MEMBRANE.
| Descriptor ID |
D058851
|
| MeSH Number(s) |
D12.776.395.550.448 D12.776.543.484.500 D12.776.543.550.418
|
| Concept/Terms |
GPI-Linked Proteins- GPI-Linked Proteins
- GPI Linked Proteins
- Proteins, GPI-Linked
- GPI-Linked Membrane Proteins
- GPI Linked Membrane Proteins
- Membrane Proteins, GPI-Linked
- Proteins, GPI-Linked Membrane
- Glycosylphosphatidylinositol Linked Proteins
- Linked Proteins, Glycosylphosphatidylinositol
- Proteins, Glycosylphosphatidylinositol Linked
|
Below are MeSH descriptors whose meaning is more general than "GPI-Linked Proteins".
Below are MeSH descriptors whose meaning is more specific than "GPI-Linked Proteins".
This graph shows the total number of publications written about "GPI-Linked Proteins" by people in this website by year, and whether "GPI-Linked Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 3 | 3 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 6 | 6 |
| 2009 | 0 | 4 | 4 |
| 2010 | 0 | 4 | 4 |
| 2011 | 2 | 1 | 3 |
| 2013 | 1 | 3 | 4 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 4 | 4 |
| 2016 | 0 | 4 | 4 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 2 | 2 | 4 |
| 2020 | 0 | 3 | 3 |
| 2021 | 0 | 3 | 3 |
| 2023 | 0 | 1 | 1 |
| 2024 | 2 | 0 | 2 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "GPI-Linked Proteins" by people in Profiles.
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Precemtabart tocentecan, an anti-CEACAM5 antibody-drug conjugate, in metastatic colorectal cancer: a phase 1 trial. Nat Med. 2025 Oct; 31(10):3504-3513.
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Soluble mesothelin-related peptide as a prognosticator in pleural mesothelioma patients receiving checkpoint immunotherapy. J Thorac Cardiovasc Surg. 2025 Apr; 169(4):1082-1095.e4.
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BST2 facilitates activation of hematopoietic stem cells through ERK signaling. Exp Hematol. 2024 Dec; 140:104653.
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Blocking of ebolavirus spread through intercellular connections by an MPER-specific antibody depends on BST2/tetherin. Cell Rep. 2023 10 31; 42(10):113254.
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Elucidating the clinical spectrum and molecular basis of HYAL2 deficiency. Genet Med. 2022 03; 24(3):631-644.
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STAT3 Gain-of-Function Mutations Underlie Deficiency in Human Nonclassical CD16+ Monocytes and CD141+ Dendritic Cells. J Immunol. 2021 11 15; 207(10):2423-2432.
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Cooperation-based sperm clusters mediate sperm oviduct entry and fertilization. Protein Cell. 2021 10; 12(10):810-817.
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Interferon Gamma Mediates Hematopoietic Stem Cell Activation and Niche Relocalization through BST2. Cell Rep. 2020 12 22; 33(12):108530.
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Ancestry and frequency of genetic variants in the general population are confounders in the characterization of germline variants linked to cancer. BMC Med Genet. 2020 05 06; 21(1):92.
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Homozygous splice-variants in human ARV1 cause GPI-anchor synthesis deficiency. Mol Genet Metab. 2020 05; 130(1):49-57.