Variant Surface Glycoproteins, Trypanosoma
"Variant Surface Glycoproteins, Trypanosoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Glycoproteins attached to the surface coat of the trypanosome. Many of these glycoproteins show amino acid sequence diversity expressed as antigenic variations. This continuous development of antigenically distinct variants in the course of infection ensures that some trypanosomes always survive the development of immune response to propagate the infection.
| Descriptor ID |
D014643
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| MeSH Number(s) |
D12.776.395.550.990 D12.776.543.550.990 D23.050.293.900 D23.050.301.900
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Variant Surface Glycoproteins, Trypanosoma".
Below are MeSH descriptors whose meaning is more specific than "Variant Surface Glycoproteins, Trypanosoma".
This graph shows the total number of publications written about "Variant Surface Glycoproteins, Trypanosoma" by people in this website by year, and whether "Variant Surface Glycoproteins, Trypanosoma" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Variant Surface Glycoproteins, Trypanosoma" by people in Profiles.
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Production of recombinant TSA-1 and evaluation of its potential for the immuno-therapeutic control of Trypanosoma cruzi infection in mice. Hum Vaccin Immunother. 2019; 15(1):210-219.
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Genome and phylogenetic analyses of Trypanosoma evansi reveal extensive similarity to T. brucei and multiple independent origins for dyskinetoplasty. PLoS Negl Trop Dis. 2015 Jan; 9(1):e3404.
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Limited antigenic variation in the Trypanosoma cruzi candidate vaccine antigen TSA-1. Parasite Immunol. 2014 Dec; 36(12):708-12.