"OX40 Ligand" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A membrane-bound tumor necrosis family member that is expressed on activated antigen-presenting cells such as B-LYMPHOCYTES and MACROPHAGES. It signals T-LYMPHOCYTES by binding the OX40 RECEPTOR.
| Descriptor ID |
D053278
|
| MeSH Number(s) |
D12.644.276.374.750.531 D12.776.395.550.597 D12.776.467.374.750.531 D12.776.543.550.590 D23.529.374.750.531
|
| Concept/Terms |
OX40 Ligand- OX40 Ligand
- CD134L Protein
- Tumor Necrosis Factor Ligand Superfamily Member 4
- OX40L Protein
- TNF Superfamily, Member 4
- Tumor Necrosis Factor (Ligand) Superfamily, Member 4
- CD134 Ligand
- gp34 Tumor Necrosis Factor
|
Below are MeSH descriptors whose meaning is more general than "OX40 Ligand".
Below are MeSH descriptors whose meaning is more specific than "OX40 Ligand".
This graph shows the total number of publications written about "OX40 Ligand" by people in this website by year, and whether "OX40 Ligand" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 2 | 2 |
| 2011 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "OX40 Ligand" by people in Profiles.
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Combination of PD-1 Inhibitor and OX40 Agonist Induces Tumor Rejection and Immune Memory in Mouse Models of Pancreatic Cancer. Gastroenterology. 2020 07; 159(1):306-319.e12.
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TNFSF4 (OX40L) expression and survival in locally advanced and metastatic melanoma. Cancer Immunol Immunother. 2019 Sep; 68(9):1493-1500.
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Short ragweed pollen promotes M2 macrophage polarization via TSLP/TSLPR/OX40L signaling in allergic inflammation. Mucosal Immunol. 2019 09; 12(5):1141-1149.
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Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination. Cancer Res. 2017 07 15; 77(14):3894-3907.
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Analysis of a Genetic Polymorphism in the Costimulatory?Molecule TNFSF4 with Hematopoietic Stem?Cell?Transplant Outcomes. Biol Blood Marrow Transplant. 2016 Jan; 22(1):27-36.
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OX40L/Jagged1 cosignaling by GM-CSF-induced bone marrow-derived dendritic cells is required for the expansion of functional regulatory T cells. J Immunol. 2013 Jun 01; 190(11):5516-25.
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Short ragweed pollen triggers allergic inflammation through Toll-like receptor 4-dependent thymic stromal lymphopoietin/OX40 ligand/OX40 signaling pathways. J Allergy Clin Immunol. 2011 Dec; 128(6):1318-1325.e2.
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Thymic stromal lymphopoietin fosters human breast tumor growth by promoting type 2 inflammation. J Exp Med. 2011 Mar 14; 208(3):479-90.
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TSLP and downstream molecules in experimental mouse allergic conjunctivitis. Invest Ophthalmol Vis Sci. 2010 Jun; 51(6):3076-82.
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Distinct signal codes generate dendritic cell functional plasticity. Sci Signal. 2010 Jan 19; 3(105):ra4.