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SANDEEP AGARWAL

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
AddressOne Baylor Plaza
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    Other Positions
    TitleAssociate Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Pathology & Immunology
    DivisionImmunology


    Collapse Research 
    Collapse research activities and funding
    R01AR082635     (AGARWAL, SANDEEP K)Feb 10, 2024 - Jan 31, 2029
    NIH
    UNDERSTANDING CADHERIN-11 IN THE DEVELOPMENT AND TREATMENT OF LUNG FIBROSIS
    Role: Principal Investigator
    R01AR062056     (AGARWAL, SANDEEP K)Sep 15, 2012 - Aug 31, 2018
    NIH
    Cadherin-11 Regulation Of Dermal Fribrosis And Macrophage Function
    Role: Principal Investigator
    K08AR054404     (AGARWAL, SANDEEP K)Aug 1, 2008 - Jul 31, 2013
    NIH
    Cadherin-11 Regulation of Fibroblast-like Synoviocytes in Synovial Inflammation
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Bruera S, Staggers KA, Suarez-Almazor ME, Agarwal SK, Bruera S, Staggers KA, Suarez-Almazor ME, Agarwal SK. Telemedicine for Patients With Systemic Lupus Erythematosus in a Publicly Funded Hospital System: Retrospective Study. Interact J Med Res. 2024 Nov 01; 13:e49065. PMID: 39078399; PMCID: PMC11568399.
      Citations:    
    2. Huang Y, Li J, Agarwal SK. Economic and Humanistic Burden of Rheumatoid Arthritis: Results From the US National Survey Data 2018-2020. ACR Open Rheumatol. 2024 Nov; 6(11):746-754. PMID: 39105293; PMCID: PMC11557984.
      Citations:    
    3. El-Halwagi A, Agarwal SK. Insights into the genetic landscape of systemic sclerosis. Best Pract Res Clin Rheumatol. 2024 Dec; 38(4):101981. PMID: 39068103.
      Citations:    Fields:    Translation:Humans
    4. Johnson SR, Bernstein EJ, Bolster MB, Chung JH, Danoff SK, George MD, Khanna D, Guyatt G, Mirza RD, Aggarwal R, Allen A, Assassi S, Buckley L, Chami HA, Corwin DS, Dellaripa PF, Domsic RT, Doyle TJ, Falardeau CM, Frech TM, Gibbons FK, Hinchcliff M, Johnson C, Kanne JP, Kim JS, Lim SY, Matson S, McMahan ZH, Merck SJ, Nesbitt K, Scholand MB, Shapiro L, Sharkey CD, Summer R, Varga J, Warrier A, Agarwal SK, Antin-Ozerkis D, Bemiss B, Chowdhary V, Dematte D'Amico JE, Hallowell R, Hinze AM, Injean PA, Jiwrajka N, Joerns EK, Lee JS, Makol A, McDermott GC, Natalini JG, Oldham JM, Saygin D, Lakin KS, Singh N, Solomon JJ, Sparks JA, Turgunbaev M, Vaseer S, Turner A, Uhl S, Ivlev I. 2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Screening and Monitoring of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases. Arthritis Rheumatol. 2024 Aug; 76(8):1201-1213. PMID: 38973714.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    5. Johnson SR, Bernstein EJ, Bolster MB, Chung JH, Danoff SK, George MD, Khanna D, Guyatt G, Mirza RD, Aggarwal R, Allen A, Assassi S, Buckley L, Chami HA, Corwin DS, Dellaripa PF, Domsic RT, Doyle TJ, Falardeau CM, Frech TM, Gibbons FK, Hinchcliff M, Johnson C, Kanne JP, Kim JS, Lim SY, Matson S, McMahan ZH, Merck SJ, Nesbitt K, Scholand MB, Shapiro L, Sharkey CD, Summer R, Varga J, Warrier A, Agarwal SK, Antin-Ozerkis D, Bemiss B, Chowdhary V, Dematte D'Amico JE, Hallowell R, Hinze AM, Injean PA, Jiwrajka N, Joerns EK, Lee JS, Makol A, McDermott GC, Natalini JG, Oldham JM, Saygin D, Lakin KS, Singh N, Solomon JJ, Sparks JA, Turgunbaev M, Vaseer S, Turner A, Uhl S, Ivlev I. 2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Screening and Monitoring of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases. Arthritis Care Res (Hoboken). 2024 08; 76(8):1070-1082. PMID: 38973729.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    6. Johnson SR, Bernstein EJ, Bolster MB, Chung JH, Danoff SK, George MD, Khanna D, Guyatt G, Mirza RD, Aggarwal R, Allen A, Assassi S, Buckley L, Chami HA, Corwin DS, Dellaripa PF, Domsic RT, Doyle TJ, Falardeau CM, Frech TM, Gibbons FK, Hinchcliff M, Johnson C, Kanne JP, Kim JS, Lim SY, Matson S, McMahan ZH, Merck SJ, Nesbitt K, Scholand MB, Shapiro L, Sharkey CD, Summer R, Varga J, Warrier A, Agarwal SK, Antin-Ozerkis D, Bemiss B, Chowdhary V, Dematte D'Amico JE, Hallowell R, Hinze AM, Injean PA, Jiwrajka N, Joerns EK, Lee JS, Makol A, McDermott GC, Natalini JG, Oldham JM, Saygin D, Lakin KS, Singh N, Solomon JJ, Sparks JA, Turgunbaev M, Vaseer S, Turner A, Uhl S, Ivlev I. 2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Treatment of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases. Arthritis Care Res (Hoboken). 2024 08; 76(8):1051-1069. PMID: 38973731.
      Citations: 3     Fields:    Translation:Humans
    7. Johnson SR, Bernstein EJ, Bolster MB, Chung JH, Danoff SK, George MD, Khanna D, Guyatt G, Mirza RD, Aggarwal R, Allen A, Assassi S, Buckley L, Chami HA, Corwin DS, Dellaripa PF, Domsic RT, Doyle TJ, Falardeau CM, Frech TM, Gibbons FK, Hinchcliff M, Johnson C, Kanne JP, Kim JS, Lim SY, Matson S, McMahan ZH, Merck SJ, Nesbitt K, Scholand MB, Shapiro L, Sharkey CD, Summer R, Varga J, Warrier A, Agarwal SK, Antin-Ozerkis D, Bemiss B, Chowdhary V, Dematte D'Amico JE, Hallowell R, Hinze AM, Injean PA, Jiwrajka N, Joerns EK, Lee JS, Makol A, McDermott GC, Natalini JG, Oldham JM, Saygin D, Lakin KS, Singh N, Solomon JJ, Sparks JA, Turgunbaev M, Vaseer S, Turner A, Uhl S, Ivlev I. 2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Treatment of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases. Arthritis Rheumatol. 2024 Aug; 76(8):1182-1200. PMID: 38978310.
      Citations: 6     Fields:    Translation:Humans
    8. Huang Y, Bruera S, Agarwal SK, Suarez-Almazor ME, Bazzazzadehgan S, Ramachandran S, Bhattacharya K, Bentley JP, Yang Y. Opioid Treatment for Adults With and Without Systemic Autoimmune/Inflammatory Rheumatic Diseases: Analysis of 2006-2019 United States National Data. Arthritis Care Res (Hoboken). 2024 10; 76(10):1427-1435. PMID: 38766880.
      Citations:    Fields:    Translation:Humans
    9. Ganugula R, Babalola KT, Heyns IM, Arora M, Agarwal SK, Mohan C, Kumar MNVR. Lymph node targeting of cyclosporine ameliorates ocular manifestations in a mouse model of systemic lupus erythematosus (SLE) via PD-L1. Nano Today. 2024 Aug; 57. PMID: 38911970; PMCID: PMC11192230.
      Citations:    
    10. Bruera S, Bowman S, Huang Y, Suarez-Almazor ME, Lo GH, Lopez-Olivo M, Chiao E, Kramer JR, Pereira FA, Agarwal SK. Factors Associated With Adherence of Cervical Cancer Screening in Women With Systemic Lupus Erythematosus. Arthritis Care Res (Hoboken). 2024 09; 76(9):1224-1231. PMID: 38682616.
      Citations:    Fields:    Translation:Humans
    11. Bhatt HN, Diwan R, Estevao IL, Dong R, Smith J, Xiao C, Agarwal SK, Nurunnabi M. Cadherin-11 targeted cell-specific liposomes enabled skin fibrosis treatment by inducing apoptosis. J Control Release. 2024 Jun; 370:110-123. PMID: 38648957.
      Citations:    Fields:    Translation:HumansAnimalsCells
    12. Chavula T, To S, Smith J, Pedroza M, Nimri J, Devaraj S, Wenderfer S, Vogel TP, Agarwal SK. CADHERIN-11 regulation of myeloid phagocytes and autoimmune inflammation in murine lupus. J Autoimmun. 2024 05; 145:103197. PMID: 38447248.
      Citations:    Fields:    Translation:HumansAnimalsCells
    13. Huang Y, Agarwal SK, Chen H, Chatterjee S, Johnson ML, Aparasu RR. Real-world Comparative Effectiveness of Methotrexate-based Combinations for Rheumatoid Arthritis: A Retrospective Cohort Study. Clin Ther. 2023 09; 45(9):e177-e186. PMID: 37573225.
      Citations:    Fields:    Translation:Humans
    14. Huang Y, Agarwal SK, Chatterjee S, Chen H, Johnson ML, Aparasu RR. Risk of incident cardiovascular events with disease-modifying anti-rheumatic drugs among adults with rheumatoid arthritis: a nested case-control study. Clin Rheumatol. 2024 Jan; 43(1):103-116. PMID: 37540382.
      Citations:    Fields:    Translation:Humans
    15. Huang Y, Chatterjee S, Agarwal SK, Chen H, Johnson ML, Aparasu RR. Factors influencing prescribing the first add-on disease-modifying antirheumatic drugs in patients initiating methotrexate for rheumatoid arthritis. Explor Res Clin Soc Pharm. 2023 Sep; 11:100296. PMID: 37521021; PMCID: PMC10372178.
      Citations:    
    16. Yadav R, Kandasamy D, Agarwal S, Gamanagatti S. Mesenteric lipoblastomatosis: an uncommon fat-containing childhood tumour diagnosed on imaging. BMJ Case Rep. 2023 May 26; 16(5). PMID: 37236672; PMCID: PMC10230882.
      Citations:    Fields:    Translation:Humans
    17. Bruera S, Sreedhar A, Agarwal SK, Muthukumar V, Geng Y, Lopez-Olivo MA. Immunosuppression for the treatment of pulmonary hypertension in patients with systemic lupus erythematosus: A?systematic review. Int J Rheum Dis. 2023 Jun; 26(6):1022-1028. PMID: 37140198.
      Citations:    Fields:    Translation:Humans
    18. Ochsner SA, Pedroza M, Pillich RT, Krishnan V, Konicek BW, Dow ER, Park SY, Agarwal SK, McKenna NJ. IL17A Blockade with Ixekizumab Suppresses MuvB Signaling in Clinical Psoriasis. J Invest Dermatol. 2023 09; 143(9):1689-1699. PMID: 36967086.
      Citations:    Fields:    Translation:Humans
    19. Bruera S, Chavula T, Madan R, Agarwal SK. Targeting type I interferons in systemic lupus erythematous. Front Pharmacol. 2022; 13:1046687. PMID: 36726783; PMCID: PMC9885195.
      Citations:    
    20. Yu G, Corn PG, Shen P, Song JH, Lee YC, Lin SC, Pan J, Agarwal SK, Panaretakis T, Pacifici M, Logothetis CJ, Yu-Lee LY, Lin SH. Retinoic Acid Receptor Activation Reduces Metastatic Prostate Cancer Bone Lesions by Blocking the Endothelial-to-Osteoblast Transition. Cancer Res. 2022 09 02; 82(17):3158-3171. PMID: 35802768; PMCID: PMC9444986.
      Citations:    Fields:    
    21. Chavula T, To S, Agarwal SK. Cadherin-11 and Its Role in Tissue Fibrosis. Cells Tissues Organs. 2023; 212(4):293-303. PMID: 35662129.
      Citations:    Fields:    
    22. Bruera S, Ventura MJ, Agarwal SK, Krause KJ, Lopez-Olivo MA. The utility of erythrocyte sedimentation rate, C-reactive protein, and procalcitonin in detecting infections in patients with systemic lupus erythematosus: A systematic review. Lupus. 2022 Sep; 31(10):1163-1174. PMID: 35650026.
      Citations:    Fields:    
    23. To S, Chavula T, Pedroza M, Smith J, Agarwal SK. Cadherin-11 Regulates Macrophage Development and Function. Front Immunol. 2022; 13:795337. PMID: 35211116; PMCID: PMC8860974.
      Citations:    Fields:    Translation:AnimalsCells
    24. Torrealba-Acosta G, Martin JC, Huttenbach Y, Garcia CR, Sohail MR, Agarwal SK, Wasko C, Bershad EM, Hirzallah MI. Acute encephalitis, myoclonus and Sweet syndrome after mRNA-1273 vaccine. BMJ Case Rep. 2021 Jul 26; 14(7). PMID: 34312136; PMCID: PMC8314742.
      Citations: 12     Fields:    Translation:Humans
    25. Bittar M, Agarwal S. Sacroiliac involvement in Blau Syndrome. Joint Bone Spine. 2021 03; 88(2):105103. PMID: 33445131.
      Citations:    Fields:    Translation:Humans
    26. Ventura MJ, Guajardo E, Clark EH, Bhairavarasu K, Kherallah RY, DiNardo AR, Ye X, Piedra PA, Atmar RL, Agarwal SK. Correspondence on 'Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 mimicking Kawasaki disease (Kawa-COVID-19): a multicentre cohort'. Ann Rheum Dis. 2022 12; 81(12):e239. PMID: 32978236.
      Citations: 3     Fields:    
    27. Ganugula R, Arora M, Zou D, Agarwal SK, Mohan C, Kumar MNVR. A highly potent lymphatic system-targeting nanoparticle cyclosporine prevents glomerulonephritis in mouse model of lupus. Sci Adv. 2020 06; 6(24):eabb3900. PMID: 32582860; PMCID: PMC7292630.
      Citations: 2     Fields:    Translation:Animals
    28. To S, Agarwal SK. Macrophages and cadherins in fibrosis and systemic sclerosis. Curr Opin Rheumatol. 2019 11; 31(6):582-588. PMID: 31436586.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    29. Wu M, Skaug B, Bi X, Mills T, Salazar G, Zhou X, Reveille J, Agarwal SK, Blackburn MR, Mayes MD, Assassi S. Interferon regulatory factor 7 (IRF7) represents a link between inflammation and fibrosis in the pathogenesis of systemic sclerosis. Ann Rheum Dis. 2019 11; 78(11):1583-1591. PMID: 31439591; PMCID: PMC7167109.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    30. Pedroza M, To S, Smith J, Agarwal SK. Cadherin-11 contributes to liver fibrosis induced by carbon tetrachloride. PLoS One. 2019; 14(7):e0218971. PMID: 31269038; PMCID: PMC6608953.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    31. Agarwal S, Dasgupta R, Paul TV, Thomas N. Acral enlargement without growth hormone excess: a clinical conundrum. BMJ Case Rep. 2019 Apr 11; 12(4). PMID: 30975784; PMCID: PMC6506000.
      Citations:    Fields:    Translation:Humans
    32. Mahendra A, Yang X, Abnouf S, Adolacion JRT, Park D, Soomro S, Roszik J, Coarfa C, Romain G, Wanzeck K, Bridges SL, Aggarwal A, Qiu P, Agarwal SK, Mohan C, Varadarajan N. Beyond Autoantibodies: Biologic Roles of Human Autoreactive B Cells in Rheumatoid Arthritis Revealed by RNA-Sequencing. Arthritis Rheumatol. 2019 04; 71(4):529-541. PMID: 30407753; PMCID: PMC6741783.
      Citations: 6     Fields:    Translation:HumansCells
    33. Pedroza M, To S, Assassi S, Wu M, Tweardy D, Agarwal SK. Role of STAT3 in skin fibrosis and transforming growth factor beta signalling. Rheumatology (Oxford). 2018 10 01; 57(10):1838-1850. PMID: 29029263; PMCID: PMC6152423.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    34. Karmouty-Quintana H, Molina JG, Philip K, Bellocchi C, Gudenkauf B, Wu M, Chen NY, Collum SD, Ko J, Agarwal SK, Assassi S, Zhong H, Blackburn MR, Weng T. The Antifibrotic Effect of A2B Adenosine Receptor Antagonism in a Mouse Model of Dermal Fibrosis. Arthritis Rheumatol. 2018 10; 70(10):1673-1684. PMID: 29771006; PMCID: PMC10077881.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    35. Pedroza M, Welschhans RL, Agarwal SK. Targeting of cadherin-11 decreases skin fibrosis in the tight skin-1 mouse model. PLoS One. 2017; 12(11):e0187109. PMID: 29112946; PMCID: PMC5675431.
      Citations: 7     Fields:    Translation:HumansAnimals
    36. Niravath P, Chen B, Chapman JW, Agarwal SK, Welschhans RL, Bongartz T, Kalari KR, Shepherd LE, Bartlett J, Pritchard K, Gelmon K, Hilsenbeck SG, Rimawi MF, Osborne CK, Goss PE, Ingle JN. Vitamin D Levels, Vitamin D Receptor Polymorphisms, and Inflammatory Cytokines in Aromatase Inhibitor-Induced Arthralgias: An Analysis of CCTG MA.27. Clin Breast Cancer. 2018 02; 18(1):78-87. PMID: 29128193; PMCID: PMC7469602.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    37. Wu M, Baron M, Pedroza C, Salazar GA, Ying J, Charles J, Agarwal SK, Hudson M, Pope J, Zhou X, Reveille JD, Fritzler MJ, Mayes MD, Assassi S. CCL2 in the Circulation Predicts Long-Term Progression of Interstitial Lung Disease in Patients With Early Systemic Sclerosis: Data From Two Independent Cohorts. Arthritis Rheumatol. 2017 09; 69(9):1871-1878. PMID: 28575534; PMCID: PMC5575955.
      Citations: 26     Fields:    Translation:Humans
    38. Smolen JS, Agarwal SK, Ilivanova E, Xu XL, Miao Y, Zhuang Y, Nnane I, Radziszewski W, Greenspan A, Beutler A, Baker D. A randomised phase II study evaluating the efficacy and safety of subcutaneously administered ustekinumab and guselkumab in patients with active rheumatoid arthritis despite treatment with methotrexate. Ann Rheum Dis. 2017 May; 76(5):831-839. PMID: 28087506; PMCID: PMC5530337.
      Citations: 52     Fields:    Translation:HumansCTClinical Trials
    39. Row S, Liu Y, Alimperti S, Agarwal SK, Andreadis ST. Cadherin-11 is a novel regulator of extracellular matrix synthesis and tissue mechanics. J Cell Sci. 2016 08 01; 129(15):2950-61. PMID: 27311482; PMCID: PMC5004872.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    40. Shagroni T, Baalwa J, Agarwal S. Double Trouble: The Diagnostic Dilemma of Diffuse Alveolar Hemorrhage. Am J Med. 2016 Jul; 129(7):e73-4. PMID: 27036393.
      Citations:    Fields:    Translation:HumansAnimals
    41. Pedroza M, Le TT, Lewis K, Karmouty-Quintana H, To S, George AT, Blackburn MR, Tweardy DJ, Agarwal SK. STAT-3 contributes to pulmonary fibrosis through epithelial injury and fibroblast-myofibroblast differentiation. FASEB J. 2016 Jan; 30(1):129-40. PMID: 26324850; PMCID: PMC4684532.
      Citations: 59     Fields:    Translation:AnimalsCells
    42. Le TT, Karmouty-Quintana H, Melicoff E, Le TT, Weng T, Chen NY, Pedroza M, Zhou Y, Davies J, Philip K, Molina J, Luo F, George AT, Garcia-Morales LJ, Bunge RR, Bruckner BA, Loebe M, Seethamraju H, Agarwal SK, Blackburn MR. Blockade of IL-6 Trans signaling attenuates pulmonary fibrosis. J Immunol. 2014 Oct 01; 193(7):3755-68. PMID: 25172494; PMCID: PMC4169999.
      Citations: 108     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    43. Agarwal SK. Integrins and cadherins as therapeutic targets in fibrosis. Front Pharmacol. 2014; 5:131. PMID: 24917820; PMCID: PMC4042084.
      Citations: 25     
    44. Alimperti S, You H, George T, Agarwal SK, Andreadis ST. Cadherin-11 regulates both mesenchymal stem cell differentiation into smooth muscle cells and the development of contractile function in vivo. J Cell Sci. 2014 Jun 15; 127(Pt 12):2627-38. PMID: 24741067; PMCID: PMC4058109.
      Citations: 27     Fields:    Translation:AnimalsCells
    45. Wu M, Pedroza M, Lafyatis R, George AT, Mayes MD, Assassi S, Tan FK, Brenner MB, Agarwal SK. Identification of cadherin 11 as a mediator of dermal fibrosis and possible role in systemic sclerosis. Arthritis Rheumatol. 2014 Apr; 66(4):1010-21. PMID: 24757152; PMCID: PMC4154539.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    46. van Bon L, Affandi AJ, Broen J, Christmann RB, Marijnissen RJ, Stawski L, Farina GA, Stifano G, Mathes AL, Cossu M, York M, Collins C, Wenink M, Huijbens R, Hesselstrand R, Saxne T, DiMarzio M, Wuttge D, Agarwal SK, Reveille JD, Assassi S, Mayes M, Deng Y, Drenth JP, de Graaf J, den Heijer M, Kallenberg CG, Bijl M, Loof A, van den Berg WB, Joosten LA, Smith V, de Keyser F, Scorza R, Lunardi C, van Riel PL, Vonk M, van Heerde W, Meller S, Homey B, Beretta L, Roest M, Trojanowska M, Lafyatis R, Radstake TR. Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis. N Engl J Med. 2014 Jan 30; 370(5):433-43. PMID: 24350901; PMCID: PMC4040466.
      Citations: 144     Fields:    Translation:HumansAnimalsCells
    47. Sendra VG, Lie A, Romain G, Agarwal SK, Varadarajan N. Detection and isolation of auto-reactive human antibodies from primary B cells. Methods. 2013 Dec 01; 64(2):153-9. PMID: 23811296; PMCID: PMC3836837.
      Citations: 7     Fields:    Translation:HumansCells
    48. Sharif R, Mayes MD, Tan FK, Gorlova OY, Hummers LK, Shah AA, Furst DE, Khanna D, Martin J, Bossini-Castillo L, Gonzalez EB, Ying J, Draeger HT, Agarwal SK, Reveille JD, Arnett FC, Wigley FM, Assassi S. IRF5 polymorphism predicts prognosis in patients with systemic sclerosis. Ann Rheum Dis. 2012 Jul; 71(7):1197-202. PMID: 22440820; PMCID: PMC3375372.
      Citations: 31     Fields:    Translation:Humans
    49. Wu M, Schneider DJ, Mayes MD, Assassi S, Arnett FC, Tan FK, Blackburn MR, Agarwal SK. Osteopontin in systemic sclerosis and its role in dermal fibrosis. J Invest Dermatol. 2012 Jun; 132(6):1605-14. PMID: 22402440; PMCID: PMC3365548.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    50. Martin JE, Broen J, Gorlova O, Beretta L, Vonk MC, Callejas JL, Carreira P, Spanish Scleroderma Group, Coenen MJ, Riemekasten G, Witte T, Hunzelmann N, Kreuter A, Koeleman BP, Voskuyl AE, Schuerwegh AJ, Hesselstrand R, Nordin A, Lunardi C, Scorza R, Shiels P, van Laar JM, Herrick A, Worthington J, Denton C, Tan FK, Arnett FC, Agarwal SK, Assassi S, Fonseca C, Mayes MD, Radstake TR, Martin J, Bossini-Castillo L, Sime?n CP, Castellv? I, Garc?a-Hern?ndez FJ, Fern?ndez Castro M, Distler JH, Palm ?, Air? P. A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations. Hum Mol Genet. 2012 Feb 15; 21(4):926-33. PMID: 22076442; PMCID: PMC3298110.
      Citations: 38     Fields:    Translation:Humans
    51. Agarwal SK. Biologic agents in rheumatoid arthritis: an update for managed care professionals. J Manag Care Pharm. 2011 Nov-Dec; 17(9 Suppl B):S14-8. PMID: 22073935; PMCID: PMC10441186.
      Citations: 31     Fields:    Translation:Humans
    52. Agarwal SK. Core management principles in rheumatoid arthritis to help guide managed care professionals. J Manag Care Pharm. 2011 Nov-Dec; 17(9 Suppl B):S03-8. PMID: 22073933.
      Citations: 10     Fields:    Translation:Humans
    53. Farheen K, Agarwal SK. Assessment of disease activity and treatment outcomes in rheumatoid arthritis. J Manag Care Pharm. 2011 Nov-Dec; 17(9 Suppl B):S09-13. PMID: 22073934; PMCID: PMC10438217.
      Citations: 14     Fields:    Translation:Humans
    54. Schneider DJ, Wu M, Le TT, Cho SH, Brenner MB, Blackburn MR, Agarwal SK. Cadherin-11 contributes to pulmonary fibrosis: potential role in TGF-? production and epithelial to mesenchymal transition. FASEB J. 2012 Feb; 26(2):503-12. PMID: 21990376; PMCID: PMC3290437.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    55. Gutala R, Carreira P, Ortego-Centeno N, Vicente-Rabaneda E, Tsao BP, Gourh P, Agarwal SK, Assassi S, Mayes MD, Arnett FC, Tan FK, Spanish Scleroderma Group, Carmona FD, Sime?n CP, Garc?a-Hern?ndez FJ, Garc?a de la Pe?a P, Fern?ndez-Castro M, Mart?nez-Estupi??n L, Egurbide MV, Mart?n J. Novel identification of the IRF7 region as an anticentromere autoantibody propensity locus in systemic sclerosis. Ann Rheum Dis. 2012 Jan; 71(1):114-9. PMID: 21926187; PMCID: PMC3369428.
      Citations: 23     Fields:    Translation:Humans
    56. Gorlova O, Martin JE, Rueda B, Koeleman BP, Ying J, Teruel M, Diaz-Gallo LM, Broen JC, Vonk MC, Simeon CP, Alizadeh BZ, Coenen MJ, Voskuyl AE, Schuerwegh AJ, van Riel PL, Vanthuyne M, van 't Slot R, Italiaander A, Ophoff RA, Hunzelmann N, Fonollosa V, Ortego-Centeno N, Airo P, van Laar J, Worthington J, Hesselstrand R, Smith V, de Keyser F, Houssiau F, Chee MM, Madhok R, Shiels PG, Westhovens R, Kreuter A, de Baere E, Witte T, Padyukov L, Nordin A, Scorza R, Lunardi C, Lie BA, Hoffmann-Vold AM, Palm O, Carreira P, Spanish Scleroderma Group, Varga J, Hinchcliff M, Lee AT, Gourh P, Amos CI, Wigley FM, Hummers LK, Nelson JL, Riemekasten G, Herrick A, Beretta L, Fonseca C, Denton CP, Gregersen PK, Agarwal S, Assassi S, Tan FK, Arnett FC, Radstake TR, Mayes MD, Martin J, Gonz?lez-Gay MA, Garc?a-Hern?ndez FJ, Gonz?lez-Escribano MF, Garc?a de la Pe?a P. Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy. PLoS Genet. 2011 Jul; 7(7):e1002178. PMID: 21779181; PMCID: PMC3136437.
      Citations: 103     Fields:    Translation:Humans
    57. Barnes J, Agarwal SK. Targeting STAT4 in systemic sclerosis: a promising new direction. Expert Rev Clin Immunol. 2011 Jul; 7(4):445-8. PMID: 21790287; PMCID: PMC3269303.
      Citations: 6     Fields:    
    58. Sharif R, Fritzler MJ, Mayes MD, Gonzalez EB, McNearney TA, Draeger H, Baron M, Canadian Scleroderma Research Group, Furst DE, Khanna DK, del Junco DJ, Molitor JA, Schiopu E, Phillips K, Seibold JR, Silver RM, Simms RW, GENISOS Study Group, Perry M, Rojo C, Charles J, Zhou X, Agarwal SK, Reveille JD, Assassi S, Arnett FC. Anti-fibrillarin antibody in African American patients with systemic sclerosis: immunogenetics, clinical features, and survival analysis. J Rheumatol. 2011 Aug; 38(8):1622-30. PMID: 21572159; PMCID: PMC3149738.
      Citations: 15     Fields:    Translation:Humans
    59. Agarwal SK, Gourh P, Guedj M, Mayes MD, Dieude P, Wipff J, Avouac J, Hachulla E, Diot E, Cracowski JL, Tiev K, Sibilia J, Mouthon L, Frances C, Amoura Z, Carpentier P, Meyer O, Kahan A, Boileau C, Arnett FC, Allanore Y, Coustet B. Association study of ITGAM, ITGAX, and CD58 autoimmune risk loci in systemic sclerosis: results from 2 large European Caucasian cohorts. J Rheumatol. 2011 Jun; 38(6):1033-8. PMID: 21362770; PMCID: PMC3404507.
      Citations: 14     Fields:    Translation:Humans
    60. McCray CJ, Agarwal SK. Stress and autoimmunity. Immunol Allergy Clin North Am. 2011 Feb; 31(1):1-18. PMID: 21094920.
      Citations: 8     Fields:    Translation:Humans
    61. Agarwal SK, Wu M, Livingston CK, Parks DH, Mayes MD, Arnett FC, Tan FK. Toll-like receptor 3 upregulation by type I interferon in healthy and scleroderma dermal fibroblasts. Arthritis Res Ther. 2011 Jan 11; 13(1):R3. PMID: 21223583; PMCID: PMC3241348.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    62. Assassi S, Reveille JD, Arnett FC, Weisman MH, Ward MM, Agarwal SK, Gourh P, Bhula J, Sharif R, Sampat K, Mayes MD, Tan FK. Whole-blood gene expression profiling in ankylosing spondylitis shows upregulation of toll-like receptor 4 and 5. J Rheumatol. 2011 Jan; 38(1):87-98. PMID: 20952467; PMCID: PMC3014385.
      Citations: 36     Fields:    Translation:HumansCells
    63. Lindsey JW, Agarwal SK, Tan FK. Gene expression changes in multiple sclerosis relapse suggest activation of T and non-T cells. Mol Med. 2011 Jan-Feb; 17(1-2):95-102. PMID: 20882258; PMCID: PMC3022990.
      Citations: 5     Fields:    Translation:HumansCells
    64. Agarwal SK. The genetics of systemic sclerosis. Discov Med. 2010 Aug; 10(51):134-43. PMID: 20807474; PMCID: PMC3803145.
      Citations: 15     Fields:    Translation:Humans
    65. Radstake TR, Gorlova O, Rueda B, Martin JE, Alizadeh BZ, Palomino-Morales R, Coenen MJ, Vonk MC, Voskuyl AE, Schuerwegh AJ, Broen JC, van Riel PL, van 't Slot R, Italiaander A, Ophoff RA, Riemekasten G, Hunzelmann N, Simeon CP, Ortego-Centeno N, Spanish Scleroderma Group, Airo P, van Laar J, Herrick A, Worthington J, Hesselstrand R, Smith V, de Keyser F, Houssiau F, Chee MM, Madhok R, Shiels P, Westhovens R, Kreuter A, Kiener H, de Baere E, Witte T, Padykov L, Klareskog L, Beretta L, Scorza R, Lie BA, Hoffmann-Vold AM, Carreira P, Varga J, Hinchcliff M, Gregersen PK, Lee AT, Ying J, Han Y, Weng SF, Amos CI, Wigley FM, Hummers L, Nelson JL, Agarwal SK, Assassi S, Gourh P, Tan FK, Koeleman BP, Arnett FC, Martin J, Mayes MD, Gonz?lez-Gay MA, Gonz?lez-Escribano MF. Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. Nat Genet. 2010 May; 42(5):426-9. PMID: 20383147; PMCID: PMC2861917.
      Citations: 160     Fields:    Translation:Humans
    66. Agarwal SK, Reveille JD. The genetics of scleroderma (systemic sclerosis). Curr Opin Rheumatol. 2010 Mar; 22(2):133-8. PMID: 20090527.
      Citations: 20     Fields:    Translation:Humans
    67. Assassi S, Mayes MD, Arnett FC, Gourh P, Agarwal SK, McNearney TA, Chaussabel D, Oommen N, Fischbach M, Shah KR, Charles J, Pascual V, Reveille JD, Tan FK. Systemic sclerosis and lupus: points in an interferon-mediated continuum. Arthritis Rheum. 2010 Feb; 62(2):589-98. PMID: 20112391; PMCID: PMC2879587.
      Citations: 77     Fields:    Translation:HumansCells
    68. Gourh P, Agarwal SK, Divecha D, Assassi S, Paz G, Arora-Singh RK, Reveille JD, Shete S, Mayes MD, Arnett FC, Tan FK. Polymorphisms in TBX21 and STAT4 increase the risk of systemic sclerosis: evidence of possible gene-gene interaction and alterations in Th1/Th2 cytokines. Arthritis Rheum. 2009 Dec; 60(12):3794-806. PMID: 19950257; PMCID: PMC2998060.
      Citations: 46     Fields:    Translation:HumansCells
    69. Agarwal SK, Gourh P, Shete S, Paz G, Divecha D, Reveille JD, Assassi S, Tan FK, Mayes MD, Arnett FC. Association of interleukin 23 receptor polymorphisms with anti-topoisomerase-I positivity and pulmonary hypertension in systemic sclerosis. J Rheumatol. 2009 Dec; 36(12):2715-23. PMID: 19918037; PMCID: PMC2895677.
      Citations: 21     Fields:    Translation:Humans
    70. Gourh P, Arnett FC, Assassi S, Tan FK, Huang M, Diekman L, Mayes MD, Reveille JD, Agarwal SK. Plasma cytokine profiles in systemic sclerosis: associations with autoantibody subsets and clinical manifestations. Arthritis Res Ther. 2009; 11(5):R147. PMID: 19799786; PMCID: PMC2787259.
      Citations: 50     Fields:    Translation:Humans
    71. Gourh P, Agarwal SK, Martin E, Divecha D, Rueda B, Bunting H, Assassi S, Paz G, Shete S, McNearney T, Draeger H, Reveille JD, Radstake TR, Simeon CP, Rodriguez L, Vicente E, Gonzalez-Gay MA, Mayes MD, Tan FK, Martin J, Arnett FC. Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populations. J Autoimmun. 2010 Mar; 34(2):155-62. PMID: 19796918; PMCID: PMC2821978.
      Citations: 58     Fields:    Translation:HumansCells
    72. Gourh P, Arnett FC, Tan FK, Assassi S, Divecha D, Paz G, McNearney T, Draeger H, Reveille JD, Mayes MD, Agarwal SK. Association of TNFSF4 (OX40L) polymorphisms with susceptibility to systemic sclerosis. Ann Rheum Dis. 2010 Mar; 69(3):550-5. PMID: 19778912; PMCID: PMC2927683.
      Citations: 54     Fields:    Translation:Humans
    73. Arnett FC, Gourh P, Shete S, Ahn CW, Honey RE, Agarwal SK, Tan FK, McNearney T, Fischbach M, Fritzler MJ, Mayes MD, Reveille JD. Major histocompatibility complex (MHC) class II alleles, haplotypes and epitopes which confer susceptibility or protection in systemic sclerosis: analyses in 1300 Caucasian, African-American and Hispanic cases and 1000 controls. Ann Rheum Dis. 2010 May; 69(5):822-7. PMID: 19596691; PMCID: PMC2916702.
      Citations: 84     Fields:    Translation:Humans
    74. Hava DL, van der Wel N, Cohen N, Dascher CC, Houben D, León L, Agarwal S, Sugita M, van Zon M, Kent SC, Shams H, Peters PJ, Brenner MB, Le?n L. Evasion of peptide, but not lipid antigen presentation, through pathogen-induced dendritic cell maturation. Proc Natl Acad Sci U S A. 2008 Aug 12; 105(32):11281-6. PMID: 18685099; PMCID: PMC2516216.
      Citations: 28     Fields:    Translation:HumansCells
    75. Agarwal SK, Glass RJ, Shadick NA, Coblyn JS, Anderson RJ, Maher NE, Weinblatt ME, Solomon DH. Predictors of discontinuation of tumor necrosis factor inhibitors in patients with rheumatoid arthritis. J Rheumatol. 2008 Sep; 35(9):1737-44. PMID: 18634159; PMCID: PMC2756035.
      Citations: 13     Fields:    Translation:Humans
    76. Agarwal SK, Lee DM, Kiener HP, Brenner MB. Coexpression of two mesenchymal cadherins, cadherin 11 and N-cadherin, on murine fibroblast-like synoviocytes. Arthritis Rheum. 2008 Apr; 58(4):1044-54. PMID: 18383368.
      Citations: 17     Fields:    Translation:AnimalsCells
    77. Agarwal SK, Tan FK, Arnett FC. Genetics and genomic studies in scleroderma (systemic sclerosis). Rheum Dis Clin North Am. 2008 Feb; 34(1):17-40; v. PMID: 18329530.
      Citations: 27     Fields:    Translation:Humans
    78. Lee DM, Kiener HP, Agarwal SK, Noss EH, Watts GF, Chisaka O, Takeichi M, Brenner MB. Cadherin-11 in synovial lining formation and pathology in arthritis. Science. 2007 Feb 16; 315(5814):1006-10. PMID: 17255475.
      Citations: 165     Fields:    Translation:AnimalsCells
    79. Agarwal SK, Brenner MB. Role of adhesion molecules in synovial inflammation. Curr Opin Rheumatol. 2006 May; 18(3):268-76. PMID: 16582691.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    80. Kiener HP, Lee DM, Agarwal SK, Brenner MB. Cadherin-11 induces rheumatoid arthritis fibroblast-like synoviocytes to form lining layers in vitro. Am J Pathol. 2006 May; 168(5):1486-99. PMID: 16651616; PMCID: PMC1606584.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    81. Agarwal SK, Maier AL, Chibnik LB, Coblyn JS, Fossel A, Lee R, Fanikos J, Fiumara K, Lowry C, Weinblatt ME. Pattern of infliximab utilization in rheumatoid arthritis patients at an academic medical center. Arthritis Rheum. 2005 Dec 15; 53(6):872-8. PMID: 16342095.
      Citations:    
    82. Agarwal SK, Monach PA, Docken WP, Coblyn JS. Characterization of relapses in adult idiopathic inflammatory myopathies. Clin Rheumatol. 2006 Jul; 25(4):476-81. PMID: 16267604.
      Citations: 1     Fields:    Translation:Humans
    83. Cohen L, Baile WF, Henninger E, Agarwal SK, Kudelka AP, Lenzi R, Sterner J, Marshall GD. Physiological and psychological effects of delivering medical news using a simulated physician-patient scenario. J Behav Med. 2003 Oct; 26(5):459-71. PMID: 14593853.
      Citations: 8     Fields:    Translation:HumansCellsCTClinical Trials
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