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JONATHAN DAVIES

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address6651 MAIN STREET
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    Collapse Biography 
    Collapse education and training
    University of Texas Southwestern Medical School, Dallas, TexasMD07/2007
    Children's National Medical Center, Washington, DC07/2010Pediatric Residency
    Children's National Medical Center, Washington, DC07/2011Chief Residency
    Baylor College of Medicine, Houston, Texas07/2014Neonatology Fellowship

    Collapse Research 
    Collapse research activities and funding
    K08HL135324     (DAVIES, JONATHAN)Jan 1, 2018 - Dec 31, 2022
    NIH
    Adenosine Signaling in Bronchopulmonary Dysplasia
    Role: Principal Investigator
    Entelligence Award     (Jonathan Davies)Oct 1, 2017 - Oct 1, 2018
    Actellion Pharmaceutical
    Adenosine Signaling Contribution to Pulmonary Hypertension due to Bronchopulmonary Dysplasia
    Role Description: The goal of this project is to determine the role of adenosine in the pathogenesis of pulmonary hypertension associated with BPD.
    Role: PI
         (Jonathan Davies)Jul 1, 2017 - Jun 30, 2019
    Baylor College of Medicine Chao Physician-Scientist Award
    Adenosine signaling in Bronchopulmonary Dysplasia
    Role Description: The goal of this project is to determine adenosine’s role in the inflammatory and developmental effects of hyperoxic lung injury after birth.
    Role: PI

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hanna M, Davies J, Fernandes A, Ketwaroo PM, Mehollin-Ray AR, Donepudi R, King A, Hagan J, Keswani SG, Gowda SH, Fernandes CJ. A novel approach to calculating expected total fetal lung volume in fetuses with isolated congenital diaphragmatic hernia and fetal growth restriction: a theoretical computational simulation. J Perinat Med. 2025 Aug 22. PMID: 40839531.
      Citations:    Fields:    
    2. Almudares F, Gandhi B, Davies J, Couroucli X, Villafranco N, Varghese NP, Guaman MC, Guillory C, Shivanna B. Oxygen Saturation Targeting in the Neonatal Intensive Care Unit. J Clin Med. 2025 Jun 04; 14(11). PMID: 40507737; PMCID: PMC12155839.
      Citations:    
    3. Tran TT, Davies J, Johnston RA, Karmouty-Quintana H, Li H, Crocker CE, Khan AM, Alcorn JL. Impact of vitamin D on hyperoxic acute lung injury in neonatal mice. BMC Pulm Med. 2024 Nov 25; 24(1):584. PMID: 39587520; PMCID: PMC11587781.
      Citations:    Fields:    Translation:Animals
    4. Olutoye OO, Hammond JD, Gilley J, Beckman RM, Bulathsinghala M, Keswani SS, Davies J, Mazziotti MV, Donepudi R, Belfort MA, King A, Ketwaroo PM, Lee TC. Fetal malrotation with midgut volvulus: Prenatal diagnosis and planning. J Pediatr Surg Case Rep. 2023 Jun; 93. PMID: 37292252; PMCID: PMC10249907.
      Citations:    
    5. Espinoza J, King A, Shamshirsaz AA, Nassr AA, Donepudi R, Sanz Cortes M, Meholin-Ray AR, Krispin E, Johnson R, Mendez Martinez Y, Keswani SG, Lee TC, Joyeux L, Espinoza AF, Olutoye Ii O, Garcia-Prats JA, Fernandes CJ, Coleman RD, Lohmann P, Rhee CJ, Davies J, Belfort MA. Characterization of Suboptimal Responses to Fetoscopic Endoluminal Tracheal Occlusion in Congenital Diaphragmatic Hernia. Fetal Diagn Ther. 2023; 50(2):128-135. PMID: 37040717.
      Citations:    Fields:    Translation:Humans
    6. Lehoczky L, Corroenne R, Espinoza J, Shamshirsaz AA, Nassr AA, Donepudi R, Belfort MA, Davies J, Sundgren NC, King A, Lee T, Keswani S, Sanz Cortes M. Simulation training for urgent postnatal fetal tracheal balloon removal: Two learning methods. Eur J Obstet Gynecol Reprod Biol. 2023 Feb; 281:92-98. PMID: 36586211.
      Citations:    Fields:    
    7. Shireby G, Dempster EL, Policicchio S, Smith RG, Pishva E, Chioza B, Davies JP, Burrage J, Lunnon K, Seiler Vellame D, Love S, Thomas A, Brookes K, Morgan K, Francis P, Hannon E, Mill J. DNA methylation signatures of Alzheimer's disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types. Nat Commun. 2022 09 24; 13(1):5620. PMID: 36153390; PMCID: PMC9509387.
      Citations:    
    8. Leung SK, Jeffries AR, Castanho I, Jordan BT, Moore K, Davies JP, Dempster EL, Bray NJ, O'Neill P, Tseng E, Ahmed Z, Collier DA, Jeffery ED, Prabhakar S, Schalkwyk L, Jops C, Gandal MJ, Sheynkman GM, Hannon E, Mill J. Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing. Cell Rep. 2021 11 16; 37(7):110022. PMID: 34788620; PMCID: PMC8609283.
      Citations:    
    9. Lingappan K, Karmouty-Quintana H, Davies J, Akkanti B, Harting MT. Understanding the age divide in COVID-19: why are children overwhelmingly spared? Am J Physiol Lung Cell Mol Physiol. 2020 07 01; 319(1):L39-L44. PMID: 32491949; PMCID: PMC7324935.
      Citations: 42     Fields:    Translation:HumansCellsPHPublic Health
    10. Weng T, Ko J, Masamha CP, Xia Z, Xiang Y, Chen NY, Molina JG, Collum S, Mertens TC, Luo F, Philip K, Davies J, Huang J, Wilson C, Thandavarayan RA, Bruckner BA, Jyothula SS, Volcik KA, Li L, Han L, Li W, Assassi S, Karmouty-Quintana H, Wagner EJ, Blackburn MR. Cleavage factor 25 deregulation contributes to pulmonary fibrosis through alternative polyadenylation. J Clin Invest. 2019 05 01; 129(5):1984-1999. PMID: 30830875; PMCID: PMC6486348.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    11. Luton A, Estrada N, Barrientez K, McGinnis J, Pitlik J, Carter A, Davenport L, Davies J. Nursing considerations and interdisciplinary coordination in the care of conjoined twins. Semin Perinatol. 2018 10; 42(6):340-349. PMID: 30185382.
      Citations:    Fields:    Translation:Humans
    12. Carreker C, De Jong H, Javor V, Fox L, Jacome J, Johns C, Springmeyer K, Davies J. Family support and media considerations with conjoined twins. Semin Perinatol. 2018 10; 42(6):393-401. PMID: 30201416.
      Citations:    Fields:    Translation:Humans
    13. Cugini K, McCormick FB, Mitchell C, Psencik E, Sarduy S, Masuoka I, Toruno R, Davies J. Therapy services and specialized devices for conjoined twins: Unique challenges with conjoined twins and the importance of physical and occupational therapy. Semin Perinatol. 2018 10; 42(6):361-368. PMID: 30166054.
      Citations:    Fields:    Translation:Humans
    14. Arnold J, Luton A, Davies J. Introduction: unique challenges in the care of conjoined twins. Semin Perinatol. 2018 10; 42(6):319-320. PMID: 30473095.
      Citations:    Fields:    Translation:Humans
    15. Mertens TCJ, Hanmandlu A, Collum SD, Chen NY, Weng T, Davies J, Liu C, Eltzschig HK, Jyothula SSK, Rajagopal K, Xia Y, Guha A, Bruckner BA, Blackburn MR, Karmouty-Quintana H, Tu L, Phan C, Guignabert C. Switching-Off Adora2b in Vascular Smooth Muscle Cells Halts the Development of Pulmonary Hypertension. Front Physiol. 2018; 9:555. PMID: 29910735; PMCID: PMC5992271.
      Citations: 9     
    16. Li H, Karmouty-Quintana H, Chen NY, Mills T, Molina J, Blackburn MR, Davies J. Loss of CD73-mediated extracellular adenosine production exacerbates inflammation and abnormal alveolar development in newborn mice exposed to prolonged hyperoxia. Pediatr Res. 2017 Aug 23. PMID: 28832580.
      Citations: 7     Fields:    
    17. Collum SD, Chen NY, Hernandez AM, Hanmandlu A, Sweeney H, Mertens TCJ, Weng T, Luo F, Molina JG, Davies J, Horan IP, Morrell NW, Amione-Guerra J, Al-Jabbari O, Youker K, Sun W, Rajadas J, Bollyky PL, Akkanti BH, Jyothula S, Sinha N, Guha A, Karmouty-Quintana H. Inhibition of hyaluronan synthesis attenuates pulmonary hypertension associated with lung fibrosis. Br J Pharmacol. 2017 Oct; 174(19):3284-3301. PMID: 28688167; PMCID: PMC5595757.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    18. Philip K, Mills TW, Davies J, Chen NY, Karmouty-Quintana H, Luo F, Molina JG, Amione-Guerra J, Sinha N, Guha A, Eltzschig HK, Blackburn MR. HIF1A up-regulates the ADORA2B receptor on alternatively activated macrophages and contributes to pulmonary fibrosis. FASEB J. 2017 11; 31(11):4745-4758. PMID: 28701304; PMCID: PMC5636704.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    19. . Refractory seizures in a term neonate due to pyridoxine dependent epilepsy. Neurological Disorders and Therapeutics. 2017; 2(1):1-5. View Publication.
    20. Chen NY, D Collum S, Luo F, Weng T, Le TT, M Hernandez A, Philip K, Molina JG, Garcia-Morales LJ, Cao Y, Ko TC, Amione-Guerra J, Al-Jabbari O, Bunge RR, Youker K, Bruckner BA, Hamid R, Davies J, Sinha N, Karmouty-Quintana H. Macrophage bone morphogenic protein receptor 2 depletion in idiopathic pulmonary fibrosis and Group III pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2016 08 01; 311(2):L238-54. PMID: 27317687; PMCID: PMC6425517.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    21. Garcia-Morales LJ, Chen NY, Weng T, Luo F, Davies J, Philip K, Volcik KA, Melicoff E, Amione-Guerra J, Bunge RR, Bruckner BA, Loebe M, Eltzschig HK, Pandit LM, Blackburn MR, Karmouty-Quintana H. Altered Hypoxic-Adenosine Axis and Metabolism in Group III Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2016 Apr; 54(4):574-83. PMID: 26414702; PMCID: PMC4821053.
      Citations: 23     Fields:    Translation:Humans
    22. Luo F, Le NB, Mills T, Chen NY, Karmouty-Quintana H, Molina JG, Davies J, Philip K, Volcik KA, Liu H, Xia Y, Eltzschig HK, Blackburn MR. Extracellular adenosine levels are associated with the progression and exacerbation of pulmonary fibrosis. FASEB J. 2016 Feb; 30(2):874-83. PMID: 26527068; PMCID: PMC4714555.
      Citations: 23     Fields:    Translation:Animals
    23. Karmouty-Quintana H, Philip K, Acero LF, Chen NY, Weng T, Molina JG, Luo F, Davies J, Le NB, Bunge I, Volcik KA, Le TT, Johnston RA, Xia Y, Eltzschig HK, Blackburn MR. Deletion of ADORA2B from myeloid cells dampens lung fibrosis and pulmonary hypertension. FASEB J. 2015 Jan; 29(1):50-60. PMID: 25318478; PMCID: PMC4763976.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    24. Davies J, Karmouty-Quintana H, Le TT, Chen NY, Weng T, Luo F, Molina J, Moorthy B, Blackburn MR. Adenosine promotes vascular barrier function in hyperoxic lung injury. Physiol Rep. 2014 Sep 01; 2(9). PMID: 25263205; PMCID: PMC4270235.
      Citations: 17     Fields:    
    25. Le TT, Karmouty-Quintana H, Melicoff E, Le TT, Weng T, Chen NY, Pedroza M, Zhou Y, Davies J, Philip K, Molina J, Luo F, George AT, Garcia-Morales LJ, Bunge RR, Bruckner BA, Loebe M, Seethamraju H, Agarwal SK, Blackburn MR. Blockade of IL-6 Trans signaling attenuates pulmonary fibrosis. J Immunol. 2014 Oct 01; 193(7):3755-68. PMID: 25172494; PMCID: PMC4169999.
      Citations: 108     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    26. Davies J, El-Dib M, Massaro A, Aly H. Renal function is impaired in small for gestational age premature infants. J Matern Fetal Neonatal Med. 2013 Mar; 26(4):388-91. PMID: 23035924.
      Citations: 6     Fields:    Translation:Humans
    27. Narayanaswamy R, Niu W, Scouras AD, Hart GT, Davies J, Ellington AD, Iyer VR, Marcotte EM. Systematic profiling of cellular phenotypes with spotted cell microarrays reveals mating-pheromone response genes. Genome Biol. 2006; 7(1):R6. PMID: 16507139; PMCID: PMC1431703.
      Citations: 15     Fields:    Translation:Animals
    28. Singh S, Chao LY, Mishra R, Davies J, Saunders GF. Missense mutation at the C-terminus of PAX6 negatively modulates homeodomain function. Hum Mol Genet. 2001 Apr 15; 10(9):911-8. PMID: 11309364.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
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