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LAVANNYA PANDIT

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
AddressOne Baylor Plaza
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    Collapse Biography 
    Collapse education and training
    Yale Univeristy, New HavenBS06/1996Biology
    University of Texas-Southwestern, DallasMD06/2000Doctorate of Medicine
    University of Iowa-Carver College of Medicine, Iowa City06/2003Internal Medicine
    Baylor College of Medicine, Houston06/2008Pulmonary/Critical Care Medicine
    Baylor College of Medicine, HoustonMS06/2012Clinical Investigation

    Collapse Research 
    Collapse research activities and funding
    R01HL169297     (PI, XINCHUN)Sep 6, 2024 - Jun 30, 2028
    NIH
    The pathophysiology of vascular remodeling in pulmonary hypertension
    Role: Co-Principal Investigator
    I01BX004954     (PANDIT, LAVANNYA M.)Oct 1, 2021 - Sep 30, 2025
    NIH
    Anatomic microniches and their contribution to vascular remodeling in pulmonary hypertension
    Role: Principal Investigator
    IK2BX002410     (PANDIT, LAVANNYA M.)Apr 1, 2014 - Mar 31, 2018
    NIH
    The TWIK 2 POTASSIUM CHANNELS ROLE IN THE DEVELOPMENT OF PULMONARY HYPERTENSION
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Bruck O, Pandit LM. Pulmonary Hypertension and Hyperglycemia-Not a Sweet Combination. Diagnostics (Basel). 2024 May 28; 14(11). PMID: 38893645; PMCID: PMC11171670.
      Citations:    
    2. Elsea SH, Razjouyan J, Lee KM, Lynch JA, Martini S, Pandit LM. Association of Glucose-6-Phosphate Dehydrogenase Deficiency With Outcomes in US Veterans With COVID-19. JAMA Netw Open. 2023 03 01; 6(3):e235626. PMID: 36988953; PMCID: PMC10061239.
      Citations:    Fields:    Translation:HumansCells
    3. Geffin R, Raheem S, Pandit LM, Hunter AS, Holliday MW, Rao AV, Shah MK. Treatment of Severe COVID-19 Infection With Remdesivir in Peritoneal Dialysis. J Investig Med High Impact Case Rep. 2023 Jan-Dec; 11:23247096231200386. PMID: 37732474; PMCID: PMC10515550.
      Citations:    Fields:    Translation:HumansCells
    4. ACTIV-3/TICO Study Group, Rogers AJ, Wentworth D, Phillips A, Shaw-Saliba K, Dewar RL, Aggarwal NR, Babiker AG, Chang W, Dharan NJ, Davey VJ, Higgs ES, Gerry N, Ginde AA, Hayanga JWA, Highbarger H, Highbarger JL, Jain MK, Kan V, Kim K, Lallemand P, Leshnower BG, Lutaakome JK, Matthews G, Mourad A, Mylonakis E, Natarajan V, Padilla ML, Pandit LM, Paredes R, Pett S, Ramachandruni S, Rehman MT, Sherman BT, Files DC, Brown SM, Matthay MA, Thompson BT, Neaton JD, Lane HC, Lundgren JD. The Association of Baseline Plasma SARS-CoV-2 Nucleocapsid Antigen Level and Outcomes in Patients Hospitalized With COVID-19. Ann Intern Med. 2022 10; 175(10):1401-1410. PMID: 36037469; PMCID: PMC9447373.
      Citations:    
    5. Ayyala U, Raheem S, Triozzi JL, Hunter A, Welch E, Bujarski S, Kao C, Pandit L, Velamuri K, Bandi VD. Implementation of a Virtual Huddle to Support Patient Care During the COVID-19 Pandemic. Fed Pract. 2022 Aug; 39(8):e0310. PMID: 36425807; PMCID: PMC9652024.
      Citations:    
    6. ACTIV-3/Therapeutics for Inpatients with COVID-19 (TICO) Study Group. Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO): a randomised controlled trial. Lancet Infect Dis. 2022 05; 22(5):622-635. PMID: 34953520; PMCID: PMC8700279.
      Citations: 32     Fields:    Translation:HumansCells
    7. ACTIV-3/TICO Bamlanivimab Study Group, Lundgren JD, Grund B, Barkauskas CE, Holland TL, Gottlieb RL, Sandkovsky U, Brown SM, Knowlton KU, Self WH, Files DC, Jain MK, Benfield T, Bowdish ME, Leshnower BG, Baker JV, Jensen JU, Gardner EM, Ginde AA, Harris ES, Johansen IS, Markowitz N, Matthay MA, Chang CC, Goodman AL, Chang W, Dewar RL, Gerry NP, Higgs ES, Highbarger H, Murray DD, Murray TA, Natarajan V, Paredes R, Parmar MKB, Phillips AN, Reilly C, Rupert AW, Sharma S, Shaw-Saliba K, Sherman BT, Teitelbaum M, Wentworth D, Cao H, Klekotka P, Babiker AG, Davey VJ, Gelijns AC, Kan VL, Polizzotto MN, Thompson BT, Lane HC, Neaton JD, ?stergaard L. Responses to a Neutralizing Monoclonal Antibody for Hospitalized Patients With COVID-19 According to Baseline Antibody and Antigen Levels : A Randomized Controlled Trial. Ann Intern Med. 2022 02; 175(2):234-243. PMID: 34928698; PMCID: PMC9334931.
      Citations: 10     Fields:    Translation:HumansCells
    8. ACTIV-3/TICO LY-CoV555 Study Group, Lundgren JD, Grund B, Barkauskas CE, Holland TL, Gottlieb RL, Sandkovsky U, Brown SM, Knowlton KU, Self WH, Files DC, Jain MK, Benfield T, Bowdish ME, Leshnower BG, Baker JV, Jensen JU, Gardner EM, Ginde AA, Harris ES, Johansen IS, Markowitz N, Matthay MA, ?stergaard L, Chang CC, Davey VJ, Goodman A, Higgs ES, Murray DD, Murray TA, Paredes R, Parmar MKB, Phillips AN, Reilly C, Sharma S, Dewar RL, Teitelbaum M, Wentworth D, Cao H, Klekotka P, Babiker AG, Gelijns AC, Kan VL, Polizzotto MN, Thompson BT, Lane HC, Neaton JD. A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19. N Engl J Med. 2021 03 11; 384(10):905-914. PMID: 33356051; PMCID: PMC7781100.
      Citations: 141     Fields:    Translation:Humans
    9. Salama C, Han J, Yau L, Reiss WG, Kramer B, Neidhart JD, Criner GJ, Kaplan-Lewis E, Baden R, Pandit L, Cameron ML, Garcia-Diaz J, Ch?vez V, Mekebeb-Reuter M, Lima de Menezes F, Shah R, Gonz?lez-Lara MF, Assman B, Freedman J, Mohan SV. Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia. N Engl J Med. 2021 01 07; 384(1):20-30. PMID: 33332779; PMCID: PMC7781101.
      Citations: 413     Fields:    Translation:Humans
    10. Karmouty-Quintana H, Thandavarayan RA, Keller SP, Sahay S, Pandit LM, Akkanti B. Emerging Mechanisms of Pulmonary Vasoconstriction in SARS-CoV-2-Induced Acute Respiratory Distress Syndrome (ARDS) and Potential Therapeutic Targets. Int J Mol Sci. 2020 Oct 29; 21(21). PMID: 33138181; PMCID: PMC7662604.
      Citations: 17     Fields:    Translation:CellsPHPublic Health
    11. Zhaorigetu S, Bair H, Jin D, Gupta VS, Pandit LM, Bryan RM, Lally KP, Olson SD, Cox CS, Harting MT. Extracellular Vesicles Attenuate Nitrofen-Mediated Human Pulmonary Artery Endothelial Dysfunction: Implications for Congenital Diaphragmatic Hernia. Stem Cells Dev. 2020 08 01; 29(15):967-980. PMID: 32475301.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    12. Rajagopal K, Bryant AJ, Sahay S, Wareing N, Zhou Y, Pandit LM, Karmouty-Quintana H. Idiopathic pulmonary fibrosis and pulmonary hypertension: Heracles meets the Hydra. Br J Pharmacol. 2021 01; 178(1):172-186. PMID: 32128790; PMCID: PMC7910027.
      Citations: 4     Fields:    Translation:HumansAnimals
    13. Darwiche T, Collum SD, Bi W, Reynolds JO, Wilson C, Wareing N, Hernandez AM, Mertens TCJ, Zhou Z, Pandit LM, Karmouty-Quintana H. Alterations in cardiovascular function in an experimental model of lung fibrosis and pulmonary hypertension. Exp Physiol. 2019 04; 104(4):568-579. PMID: 30663834.
      Citations: 2     Fields:    Translation:Animals
    14. Kitagawa MG, Reynolds JO, Durgan D, Rodney G, Karmouty-Quintana H, Bryan R, Pandit LM. Twik-2-/- mouse demonstrates pulmonary vascular heterogeneity in intracellular pathways for vasocontractility. Physiol Rep. 2019 01; 7(1):e13950. PMID: 30632293; PMCID: PMC6328926.
      Citations: 3     Fields:    Translation:AnimalsCells
    15. Kitagawa MG, Reynolds JO, Wehrens XHT, Bryan RM, Pandit LM. Hemodynamic and Pathologic Characterization of the TASK-1-/- Mouse Does Not Demonstrate Pulmonary Hypertension. Front Med (Lausanne). 2017; 4:177. PMID: 29109948; PMCID: PMC5660113.
      Citations: 11     
    16. Medrek SK, Sharafkhaneh A, Spiegelman AM, Kak A, Pandit LM. Admission for COPD Exacerbation Is Associated with the Clinical Diagnosis of Pulmonary Hypertension: Results from a Retrospective Longitudinal Study of a Veteran Population. COPD. 2017 Oct; 14(5):484-489. PMID: 28715281.
      Citations: 14     Fields:    Translation:Humans
    17. Granillo A, Pena CA, Pham T, Pandit LM, Taffet GE. Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery. J Vis Exp. 2017 02 20; (120). PMID: 28287520; PMCID: PMC5408887.
      Citations: 4     Fields:    Translation:Animals
    18. Garcia-Morales LJ, Chen NY, Weng T, Luo F, Davies J, Philip K, Volcik KA, Melicoff E, Amione-Guerra J, Bunge RR, Bruckner BA, Loebe M, Eltzschig HK, Pandit LM, Blackburn MR, Karmouty-Quintana H. Altered Hypoxic-Adenosine Axis and Metabolism in Group III Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2016 Apr; 54(4):574-83. PMID: 26414702; PMCID: PMC4821053.
      Citations: 23     Fields:    Translation:Humans
    19. Bhavani S, Tsai CL, Perusich S, Hesselbacher S, Coxson H, Pandit L, Corry DB, Kheradmand F. Clinical and Immunological Factors in Emphysema Progression. Five-Year Prospective Longitudinal Exacerbation Study of Chronic Obstructive Pulmonary Disease (LES-COPD). Am J Respir Crit Care Med. 2015 Nov 15; 192(10):1171-8. PMID: 26241705; PMCID: PMC4731622.
      Citations: 23     Fields:    Translation:HumansCells
    20. Pandit LM, Lloyd EE, Reynolds JO, Lawrence WS, Reynolds C, Wehrens XH, Bryan RM. TWIK-2 channel deficiency leads to pulmonary hypertension through a rho-kinase-mediated process. Hypertension. 2014 Dec; 64(6):1260-5. PMID: 25245387; PMCID: PMC4231005.
      Citations: 16     Fields:    Translation:Animals
    21. Wei Q, Sha Y, Bhattacharya A, Abdel Fattah E, Bonilla D, Jyothula SS, Pandit L, Khurana Hershey GK, Eissa NT. Regulation of IL-4 receptor signaling by STUB1 in lung inflammation. Am J Respir Crit Care Med. 2014 Jan 01; 189(1):16-29. PMID: 24251647; PMCID: PMC3919125.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    22. Lloyd EE, Pandit LM, Crossland RF, Marrelli SP, Bryan RM. Endothelium-dependent relaxations in the aorta from K(2p)6.1 knockout mice. Am J Physiol Regul Integr Comp Physiol. 2013 Jul 01; 305(1):R60-7. PMID: 23637138; PMCID: PMC3727024.
      Citations: 6     Fields:    Translation:Animals
    23. Pandit L, Bonilla DL, Eissa NT. Autophagy: a new frontier in research in lung diseases. Am J Respir Crit Care Med. 2011 Mar 01; 183(5):566-8. PMID: 21471054.
      Citations: 1     Fields:    Translation:Humans
    24. Tyryshkin A, Gorgun FM, Abdel Fattah E, Mazumdar T, Pandit L, Zeng S, Eissa NT. Src kinase-mediated phosphorylation stabilizes inducible nitric-oxide synthase in normal cells and cancer cells. J Biol Chem. 2010 Jan 01; 285(1):784-92. PMID: 19875457; PMCID: PMC2804227.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    25. Pandit L, Kolodziejska KE, Zeng S, Eissa NT. The physiologic aggresome mediates cellular inactivation of iNOS. Proc Natl Acad Sci U S A. 2009 Jan 27; 106(4):1211-5. PMID: 19139419; PMCID: PMC2633562.
      Citations: 17     Fields:    Translation:HumansCells
    26. Sha Y, Pandit L, Zeng S, Eissa NT. A critical role for CHIP in the aggresome pathway. Mol Cell Biol. 2009 Jan; 29(1):116-28. PMID: 18955503; PMCID: PMC2612489.
      Citations: 28     Fields:    Translation:HumansCells
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