"Lymphotoxin-beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A membrane-bound tumor necrosis family member found primarily on LYMPHOCYTES. It can form a heterotrimer (LYMPHOTOXIN ALPHA1, BETA2 HETEROTRIMER) with the soluble ligand LYMPHOTOXIN-ALPHA and anchor it to the cell surface. The membrane-bound complex is specific for the LYMPHOTOXIN BETA receptor.
| Descriptor ID |
D053308
|
| MeSH Number(s) |
D12.644.276.374.750.515 D12.776.467.374.750.515 D23.529.374.750.515
|
| Concept/Terms |
Lymphotoxin-beta- Lymphotoxin-beta
- Tumor Necrosis Factor Ligand Superfamily Member 3
- Tumor Necrosis Factor C
- Lymphotoxin beta
- beta, Lymphotoxin
- TNF Superfamily, Member 3
|
Below are MeSH descriptors whose meaning is more general than "Lymphotoxin-beta".
Below are MeSH descriptors whose meaning is more specific than "Lymphotoxin-beta".
This graph shows the total number of publications written about "Lymphotoxin-beta" by people in this website by year, and whether "Lymphotoxin-beta" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lymphotoxin-beta" by people in Profiles.
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Lymphotoxin-? Interacts with Methylated EGFR to Mediate Acquired Resistance to Cetuximab in Head and Neck Cancer. Clin Cancer Res. 2017 Aug 01; 23(15):4388-4401.
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Dual Role of the Adaptive Immune System in Liver Injury and Hepatocellular Carcinoma Development. Cancer Cell. 2016 08 08; 30(2):308-323.
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Lymphotoxin pathway-directed, autoimmune regulator-independent central tolerance to arthritogenic collagen. J Immunol. 2006 Jul 01; 177(1):290-7.
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Lymphotoxin beta-mediated stimulation of synoviocytes in rheumatoid arthritis. Arthritis Rheum. 2004 Jul; 50(7):2140-50.
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Altered patterns of gene expression distinguishing ascending aortic aneurysms from abdominal aortic aneurysms: complementary DNA expression profiling in the molecular characterization of aortic disease. J Thorac Cardiovasc Surg. 2003 Aug; 126(2):344-57; discission 357.
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Lymphoid neogenesis in rheumatoid synovitis. J Immunol. 2001 Jul 15; 167(2):1072-80.