Tumor Necrosis Factor-alpha
"Tumor Necrosis Factor-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.
| Descriptor ID |
D014409
|
| MeSH Number(s) |
D12.644.276.374.500.800 D12.644.276.374.750.626 D12.776.124.900 D12.776.395.930 D12.776.467.374.500.800 D12.776.467.374.750.626 D23.529.374.500.800 D23.529.374.750.626
|
| Concept/Terms |
Tumor Necrosis Factor-alpha- Tumor Necrosis Factor-alpha
- Tumor Necrosis Factor alpha
- Cachectin
- Cachectin-Tumor Necrosis Factor
- Cachectin Tumor Necrosis Factor
- Tumor Necrosis Factor Ligand Superfamily Member 2
- Tumor Necrosis Factor
- TNF Superfamily, Member 2
- TNFalpha
- TNF-alpha
|
Below are MeSH descriptors whose meaning is more general than "Tumor Necrosis Factor-alpha".
Below are MeSH descriptors whose meaning is more specific than "Tumor Necrosis Factor-alpha".
This graph shows the total number of publications written about "Tumor Necrosis Factor-alpha" by people in this website by year, and whether "Tumor Necrosis Factor-alpha" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 15 | 9 | 24 |
| 1995 | 16 | 17 | 33 |
| 1996 | 14 | 7 | 21 |
| 1997 | 13 | 12 | 25 |
| 1998 | 13 | 14 | 27 |
| 1999 | 14 | 17 | 31 |
| 2000 | 20 | 21 | 41 |
| 2001 | 26 | 26 | 52 |
| 2002 | 32 | 29 | 61 |
| 2003 | 29 | 33 | 62 |
| 2004 | 23 | 39 | 62 |
| 2005 | 29 | 40 | 69 |
| 2006 | 23 | 34 | 57 |
| 2007 | 13 | 30 | 43 |
| 2008 | 24 | 25 | 49 |
| 2009 | 16 | 38 | 54 |
| 2010 | 12 | 31 | 43 |
| 2011 | 16 | 26 | 42 |
| 2012 | 12 | 33 | 45 |
| 2013 | 9 | 24 | 33 |
| 2014 | 9 | 20 | 29 |
| 2015 | 7 | 19 | 26 |
| 2016 | 6 | 16 | 22 |
| 2017 | 4 | 13 | 17 |
| 2018 | 4 | 8 | 12 |
| 2019 | 2 | 11 | 13 |
| 2020 | 2 | 8 | 10 |
| 2021 | 1 | 11 | 12 |
| 2022 | 1 | 11 | 12 |
| 2023 | 1 | 7 | 8 |
| 2024 | 1 | 5 | 6 |
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Below are the most recent publications written about "Tumor Necrosis Factor-alpha" by people in Profiles.
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LPS-induced whole-blood cytokine production and depressive symptoms in dementia spousal caregivers: The moderating effect of childhood trauma. Psychoneuroendocrinology. 2024 Oct; 168:107140.
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(Re-)introduction of TNF antagonists and JAK inhibitors in patients with previous tuberculosis: a systematic review. Clin Microbiol Infect. 2024 Aug; 30(8):989-998.
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Failure Rate of Anti-Tumor Necrosis Factor a Biologics in Very Early Onset Inflammatory Bowel Disease. Inflamm Bowel Dis. 2024 Mar 01; 30(3):510-512.
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A TNF-IL-1 circuit controls Yersinia within intestinal pyogranulomas. J Exp Med. 2024 Mar 04; 221(3).
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Immunological mechanisms of the nucleocapsid protein in COVID-19. Sci Rep. 2024 02 14; 14(1):3711.
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[Zhuyu Pills promote polarization of macrophages toward M2 phenotype to prevent atherosclerosis via PPAR?/NF-?B signaling pathway]. Zhongguo Zhong Yao Za Zhi. 2024 Jan; 49(1):243-250.
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The Role of High Mobility Group Box B-1 in the Prognosis of Colorectal Cancer Based on the Changes in the Intestinal Mucosal Barrier. Technol Cancer Res Treat. 2024 Jan-Dec; 23:15330338231198972.
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Effect of epithelial-specific MyD88 signaling pathway on airway inflammatory response to organic dust exposure. J Immunotoxicol. 2023 12; 20(1):2148782.
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TNF is a critical cytokine in age-related dry eye disease. Ocul Surf. 2023 Oct; 30:119-128.
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Hyperglycemia: A determinant of cardiac autonomic dysfunction in youth with obesity across the spectrum of glycemic regulation. Pediatr Obes. 2023 10; 18(10):e13063.