"alpha 1-Antitrypsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Plasma glycoprotein member of the serpin superfamily which inhibits TRYPSIN; NEUTROPHIL ELASTASE; and other PROTEOLYTIC ENZYMES.
| Descriptor ID |
D000515
|
| MeSH Number(s) |
D12.644.861.035 D12.776.124.050.070 D12.776.124.790.106.085 D12.776.377.715.085.085 D12.776.395.068 D12.776.872.035
|
| Concept/Terms |
alpha 1-Antitrypsin- alpha 1-Antitrypsin
- alpha 1 Antitrypsin
- alpha 1 Antiprotease
- Antiprotease, alpha 1
- Serpin A1
- alpha 1-Protease Inhibitor
- Inhibitor, alpha 1-Protease
- alpha 1 Protease Inhibitor
- alpha 1-Proteinase Inhibitor
- Inhibitor, alpha 1-Proteinase
- alpha 1 Proteinase Inhibitor
- Trypsin Inhibitor, alpha 1-Antitrypsin
- Trypsin Inhibitor, alpha 1 Antitrypsin
- A1PI
- alpha 1-Antiproteinase
- 1-Antiproteinase, alpha
- alpha 1 Antiproteinase
|
Below are MeSH descriptors whose meaning is more general than "alpha 1-Antitrypsin".
Below are MeSH descriptors whose meaning is more specific than "alpha 1-Antitrypsin".
This graph shows the total number of publications written about "alpha 1-Antitrypsin" by people in this website by year, and whether "alpha 1-Antitrypsin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "alpha 1-Antitrypsin" by people in Profiles.
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Activation of the c-Jun N-terminal kinase pathway aggravates proteotoxicity of hepatic mutant Z alpha1-antitrypsin. Hepatology. 2017 06; 65(6):1865-1874.
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Capitalizing on the autophagic response for treatment of liver disease caused by alpha-1-antitrypsin deficiency and other genetic diseases. Biomed Res Int. 2014; 2014:459823.
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Differential subcellular targeting of recombinant human a1-proteinase inhibitor influences yield, biological activity and in planta stability of the protein in transgenic tomato plants. Plant Sci. 2012 Nov; 196:53-66.
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Expression and purification of recombinant human alpha1-proteinase inhibitor and its single amino acid substituted variants in Escherichia coli for enhanced stability and biological activity. J Biotechnol. 2010 May 03; 147(1):64-72.
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Effect of point mutations in translation initiation context on the expression of recombinant human alpha(1)-proteinase inhibitor in transgenic tomato plants. Plant Cell Rep. 2009 Dec; 28(12):1791-8.
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Expression of modified gene encoding functional human alpha-1-antitrypsin protein in transgenic tomato plants. Transgenic Res. 2008 Oct; 17(5):881-96.
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Plasma protein profiling for diagnosis of pancreatic cancer reveals the presence of host response proteins. Clin Cancer Res. 2005 Feb 01; 11(3):1110-8.
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A role for corticosteroid-binding globulin in delivery of cortisol to activated neutrophils. J Clin Endocrinol Metab. 1990 Jul; 71(1):34-9.
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Immunohistochemical demonstration of alpha-1-proteinase inhibitor in brain tumors. Cancer. 1987 Aug 15; 60(4):804-9.
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Alpha-1-antitrypsin in human brain tumors. J Neurosurg. 1987 Aug; 67(2):258-62.