"Protein C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation.
| Descriptor ID |
D011486
|
| MeSH Number(s) |
D08.622.705 D12.776.124.650 D12.776.395.635 D23.113.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein C".
Below are MeSH descriptors whose meaning is more specific than "Protein C".
This graph shows the total number of publications written about "Protein C" by people in this website by year, and whether "Protein C" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 1 | 2 |
| 1999 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2006 | 1 | 1 | 2 |
| 2007 | 1 | 1 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 3 | 0 | 3 |
| 2016 | 2 | 1 | 3 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Protein C" by people in Profiles.
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APC ameliorates pulmonary complications in cGVHD. Blood. 2019 08 29; 134(9):724-725.
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Identification of Genetic Variants Linking Protein C and Lipoprotein Metabolism: The ARIC Study (Atherosclerosis Risk in Communities). Arterioscler Thromb Vasc Biol. 2017 03; 37(3):589-597.
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Occupancy of human EPCR by protein C induces ?-arrestin-2 biased PAR1 signaling by both APC and thrombin. Blood. 2016 10 06; 128(14):1884-1893.
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PIVKA-II correlates with INR but not protein C or protein S concentrations in cord blood among newborns. J Neonatal Perinatal Med. 2016 May 18; 9(2):139-43.
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Efficacy and safety of protein C concentrate to treat purpura fulminans and thromboembolic events in severe congenital protein C deficiency. Thromb Haemost. 2016 07 04; 116(1):58-68.
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TNF Regulates Essential Alternative Complement Pathway Components and Impairs Activation of Protein C in Human Glomerular Endothelial Cells. J Immunol. 2016 Jan 15; 196(2):832-45.
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Protein C Thr315Ala variant results in gain of function but manifests as type II deficiency in diagnostic assays. Blood. 2015 Apr 09; 125(15):2428-34.
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Intraperitoneal administration of activated protein C prevents postsurgical adhesion band formation. Blood. 2015 Feb 19; 125(8):1339-48.
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Genetic markers associated with plasma protein C level in African Americans: the atherosclerosis risk in communities (ARIC) study. Genet Epidemiol. 2014 Dec; 38(8):709-13.
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Short-term venous stasis induces fibrinolytic activation but not thrombin formation. J Atheroscler Thromb. 2014; 21(12):1260-70.