"Factor IX" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Storage-stable blood coagulation factor acting in the intrinsic pathway of blood coagulation. Its activated form, IXa, forms a complex with factor VIII and calcium on platelet factor 3 to activate factor X to Xa. Deficiency of factor IX results in HEMOPHILIA B (Christmas Disease).
| Descriptor ID |
D005164
|
| MeSH Number(s) |
D08.622.355 D12.776.124.125.375 D23.119.375
|
| Concept/Terms |
Factor IX- Factor IX
- Factor Nine
- Autoprothrombin II
- Christmas Factor
- Factor IX Fraction
- Plasma Thromboplastin Component
- Blood Coagulation Factor IX
- Factor IX Complex
- Factor 9
- Coagulation Factor IX
- Factor IX, Coagulation
|
Below are MeSH descriptors whose meaning is more general than "Factor IX".
Below are MeSH descriptors whose meaning is more specific than "Factor IX".
This graph shows the total number of publications written about "Factor IX" by people in this website by year, and whether "Factor IX" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 |
| 1995 | 1 | 1 | 2 |
| 1996 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Factor IX" by people in Profiles.
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Retrospective Comparison of Recombinant Activated Factor VII Versus 4-Factor Prothrombin Complex Concentrate in Cardiac Surgical Patients. J Cardiothorac Vasc Anesth. 2024 Feb; 38(2):388-393.
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Production and control of coagulation proteins for factor X activation in human endothelial cells and fibroblasts. Sci Rep. 2020 02 06; 10(1):2005.
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Haemophilia B acquired from liver transplantation: a case report and literature review. Haemophilia. 2015 Jul; 21(4):e328-30.
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AAV vectors containing rDNA homology display increased chromosomal integration and transgene persistence. Mol Ther. 2012 Oct; 20(10):1902-11.
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Balloon catheter delivery of helper-dependent adenoviral vector results in sustained, therapeutic hFIX expression in rhesus macaques. Mol Ther. 2012 Oct; 20(10):1863-70.
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Bioengineered factor IX molecules with increased catalytic activity improve the therapeutic index of gene therapy vectors for hemophilia B. Hum Gene Ther. 2009 May; 20(5):479-85.
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Quality assurance in hemostasis: the perspective from the College of American Pathologists proficiency testing program. Semin Thromb Hemost. 2007 Apr; 33(3):250-8.
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Sustained phenotypic correction of canine hemophilia B after systemic administration of helper-dependent adenoviral vector. Hum Gene Ther. 2005 Jul; 16(7):811-20.
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Increased hepatic transduction with reduced systemic dissemination and proinflammatory cytokines following hydrodynamic injection of helper-dependent adenoviral vectors. Mol Ther. 2005 Jul; 12(1):99-106.
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Clotting factor IX levels in C/EBP alpha knockout mice. Br J Haematol. 1997 Dec; 99(3):578-9.