Plasminogen Activator Inhibitor 1
"Plasminogen Activator Inhibitor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasminogen activators.
| Descriptor ID |
D017395
|
| MeSH Number(s) |
D12.644.861.695.500 D12.776.124.125.640 D12.776.872.695.500 D23.119.832.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Plasminogen Activator Inhibitor 1".
Below are MeSH descriptors whose meaning is more specific than "Plasminogen Activator Inhibitor 1".
This graph shows the total number of publications written about "Plasminogen Activator Inhibitor 1" by people in this website by year, and whether "Plasminogen Activator Inhibitor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1998 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 0 | 3 | 3 |
| 2007 | 2 | 0 | 2 |
| 2008 | 1 | 1 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 2 | 1 | 3 |
| 2016 | 3 | 2 | 5 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 2 | 2 |
| 2021 | 1 | 1 | 2 |
| 2022 | 2 | 2 | 4 |
| 2024 | 0 | 1 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Plasminogen Activator Inhibitor 1" by people in Profiles.
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The microRNA miR-30a blocks adipose tissue fibrosis accumulation in obesity. J Clin Invest. 2025 Aug 01; 135(15).
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Plasma protein biomarkers for primary graft dysfunction after lung transplantation: a single-center cohort analysis. Sci Rep. 2022 09 27; 12(1):16137.
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Arterial thrombosis in a newborn with homozygous plasminogen activator inhibitor-1 4G/4G polymorphism. Pediatr Blood Cancer. 2022 08; 69(8):e29586.
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Aspirin Modifies Inflammatory Mediators and Metabolomic Profiles and Contributes to the Suppression of Obesity-Associated Breast Cancer Cell Growth. Int J Mol Sci. 2020 Jun 30; 21(13).
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IGF1R as a Key Target in High Risk, Metastatic Medulloblastoma. Sci Rep. 2016 06 03; 6:27012.
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Rapid Increases in proBDNF after Pilocarpine-Induced Status Epilepticus in Mice Are Associated with Reduced proBDNF Cleavage Machinery. eNeuro. 2016 Jan-Feb; 3(1).
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A novel tumor-promoting role for nuclear factor IA in glioblastomas is mediated through negative regulation of p53, p21, and PAI1. Neuro Oncol. 2014 Jan; 16(2):191-203.
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Metabolic factors, adipose tissue, and plasminogen activator inhibitor-1 levels in type 2 diabetes: findings from the look AHEAD study. Arterioscler Thromb Vasc Biol. 2011 Jul; 31(7):1689-95.
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Effect of orange juice and beverage with phytosterols on cytokines and PAI-1 activity. Clin Nutr. 2011 Oct; 30(5):668-71.
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Imbalance of plasminogen activator inhibitor type-1 (PAI-1) and tissue plasminogen activator (t-PA) activity in patients with Noonan syndrome. J Pediatr Hematol Oncol. 2010 Oct; 32(7):532-6.