Platelet Activating Factor
"Platelet Activating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phospholipid derivative formed by PLATELETS; BASOPHILS; NEUTROPHILS; MONOCYTES; and MACROPHAGES. It is a potent platelet aggregating agent and inducer of systemic anaphylactic symptoms, including HYPOTENSION; THROMBOCYTOPENIA; NEUTROPENIA; and BRONCHOCONSTRICTION.
| Descriptor ID |
D010972
|
| MeSH Number(s) |
D02.033.100.291.211.500 D02.092.063.291.211.500 D02.092.877.883.333.710 D02.675.276.232.710 D10.570.755.375.760.400.985.910 D23.119.865 D23.469.050.600
|
| Concept/Terms |
Platelet Activating Factor- Platelet Activating Factor
- Factor, Platelet Activating
- Phosphorylcholine, Acetyl Glyceryl Ether
- Platelet Aggregating Factor
- Aggregating Factor, Platelet
- Platelet Aggregation Enhancing Factor
- AGEPC
- Thrombocyte Aggregating Activity
- 1-Alkyl-2-acetyl-sn-glycerophosphocholine
- 1 Alkyl 2 acetyl sn glycerophosphocholine
- Acetyl Glyceryl Ether Phosphorylcholine
- PAF-Acether
- PAF Acether
- Platelet-Activating Substance
- Platelet Activating Substance
|
Below are MeSH descriptors whose meaning is more general than "Platelet Activating Factor".
Below are MeSH descriptors whose meaning is more specific than "Platelet Activating Factor".
This graph shows the total number of publications written about "Platelet Activating Factor" by people in this website by year, and whether "Platelet Activating Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 |
| 1995 | 2 | 0 | 2 |
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 2 | 1 | 3 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 2 | 1 | 3 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 2 | 2 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 2 | 2 | 4 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Platelet Activating Factor" by people in Profiles.
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Platelet activating factor-induced expression of p21 is correlated with histone acetylation. Sci Rep. 2017 02 03; 7:41959.
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Understanding the connection between platelet-activating factor, a UV-induced lipid mediator of inflammation, immune suppression and skin cancer. Prog Lipid Res. 2016 07; 63:14-27.
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Platelet-Activating Factor Induces Epigenetic Modifications in Human Mast Cells. J Invest Dermatol. 2015 Dec; 135(12):3034-3040.
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Platelets Play Differential Role During the Initiation and Progression of Autoimmune Neuroinflammation. Circ Res. 2015 Oct 09; 117(9):779-92.
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Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition. J Clin Invest. 2015 Jul 01; 125(7):2808-24.
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Platelet-activating factor induces cell cycle arrest and disrupts the DNA damage response in mast cells. Cell Death Dis. 2015 May 07; 6:e1745.
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An essential role for platelet-activating factor in activating mast cell migration following ultraviolet irradiation. J Leukoc Biol. 2014 Jan; 95(1):139-48.
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Novel treatments for NEC: keeping IBD in mind. Curr Gastroenterol Rep. 2012 Oct; 14(5):373-9.
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Agents that reverse UV-Induced immune suppression and photocarcinogenesis affect DNA repair. J Invest Dermatol. 2010 May; 130(5):1428-37.
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Inflammation and melanoma metastasis. Pigment Cell Melanoma Res. 2009 Jun; 22(3):257-67.