"Phosphatidic Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Fatty acid derivatives of glycerophosphates. They are composed of glycerol bound in ester linkage with 1 mole of phosphoric acid at the terminal 3-hydroxyl group and with 2 moles of fatty acids at the other two hydroxyl groups.
| Descriptor ID |
D010712
|
| MeSH Number(s) |
D10.570.755.375.760
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Phosphatidic Acids".
Below are MeSH descriptors whose meaning is more specific than "Phosphatidic Acids".
This graph shows the total number of publications written about "Phosphatidic Acids" by people in this website by year, and whether "Phosphatidic Acids" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phosphatidic Acids" by people in Profiles.
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Bile acids target proteolipid nano-assemblies of EGFR and phosphatidic acid in the plasma membrane for stimulation of MAPK signaling. PLoS One. 2018; 13(8):e0198983.
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Binding of PLD2-Generated Phosphatidic Acid to KIF5B Promotes MT1-MMP Surface Trafficking and Lung Metastasis of Mouse Breast Cancer Cells. Dev Cell. 2017 10 23; 43(2):186-197.e7.
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ESI-MS/MS and MALDI-IMS Localization Reveal Alterations in Phosphatidic Acid, Diacylglycerol, and DHA in Glioma Stem Cell Xenografts. J Proteome Res. 2015 Jun 05; 14(6):2511-9.
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Not expecting the unexpected: diacylglycerol kinase alpha as a cancer target. Cancer Discov. 2013 Jul; 3(7):726-7.
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Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acid. Bioorg Med Chem Lett. 2010 Dec 15; 20(24):7525-8.
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Targeting melanoma growth and viability reveals dualistic functionality of the phosphonothionate analogue of carba cyclic phosphatidic acid. Mol Cancer. 2010 Jun 09; 9:140.
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Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis. J Biol Chem. 2006 Aug 11; 281(32):22786-93.
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Enantioselective responses to a phosphorothioate analogue of lysophosphatidic acid with LPA3 receptor-selective agonist activity. J Med Chem. 2003 Dec 18; 46(26):5575-8.
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Identification of a phosphothionate analogue of lysophosphatidic acid (LPA) as a selective agonist of the LPA3 receptor. J Biol Chem. 2003 Apr 04; 278(14):11962-9.
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The overall partitioning of anthracyclines into phosphatidyl-containing model membranes depends neither on the drug charge nor the presence of anionic phospholipids. Eur J Biochem. 1996 Nov 01; 241(3):879-87.