"Eicosanoids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of compounds named after and generally derived from C20 fatty acids (EICOSANOIC ACIDS) that includes PROSTAGLANDINS; LEUKOTRIENES; THROMBOXANES, and HYDROXYEICOSATETRAENOIC ACIDS. They have hormone-like effects mediated by specialized receptors (RECEPTORS, EICOSANOID).
| Descriptor ID |
D015777
|
| MeSH Number(s) |
D10.251.355.255 D23.469.050.175
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Eicosanoids".
Below are MeSH descriptors whose meaning is more specific than "Eicosanoids".
This graph shows the total number of publications written about "Eicosanoids" by people in this website by year, and whether "Eicosanoids" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2012 | 2 | 0 | 2 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Eicosanoids" by people in Profiles.
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Eicosanoid-Activated PPARa Inhibits NF?B-Dependent Bacterial Clearance During Post-Influenza Superinfection. Front Cell Infect Microbiol. 2022; 12:881462.
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Characterization of an arachidonic acid-deficient (Fads1 knockout) mouse model. J Lipid Res. 2012 Jul; 53(7):1287-95.
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Activated glucocorticoid and eicosanoid pathways in endometriosis. Fertil Steril. 2012 Jul; 98(1):117-25.
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Pleiotropic effects of statins: the role of eicosanoid production. Curr Atheroscler Rep. 2012 Apr; 14(2):135-9.
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Modulation of eicosanoid production and activity as a potential explanation for some of the pleiotropic effects of statins. Cardiology. 2010; 116(1):45-7.
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The myocardial infarct size-limiting effect of sitagliptin is PKA-dependent, whereas the protective effect of pioglitazone is partially dependent on PKA. Am J Physiol Heart Circ Physiol. 2010 May; 298(5):H1454-65.
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Combination chemoprevention of HER2/neu-induced breast cancer using a cyclooxygenase-2 inhibitor and a retinoid X receptor-selective retinoid. Cancer Prev Res (Phila). 2008 Aug; 1(3):208-14.
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Comparative analysis of peritoneum and tumor eicosanoids and pathways in advanced ovarian cancer. Clin Cancer Res. 2007 Oct 01; 13(19):5736-44.
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Determination of endogenous tissue inflammation profiles by LC/MS/MS: COX- and LOX-derived bioactive lipids. Prostaglandins Leukot Essent Fatty Acids. 2006 Dec; 75(6):385-95.
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Cyclooxygenase-2 induction and prostaglandin E2 accumulation in squamous cell carcinoma as a consequence of epidermal growth factor receptor activation by imatinib mesylate. J Exp Ther Oncol. 2004 Dec; 4(4):317-25.