"Isoprostanes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A series of prostaglandin-like compounds that are produced by the attack of free-radical species on unsaturated fatty acids, especially ARACHIDONIC ACID, of cellular MEMBRANES. Once cleaved from the lipid membrane by the action of phospholipases they can circulate into various bodily fluids and eventually be excreted. Although these compounds resemble enzymatically synthesized prostaglandins their stereoisometric arrangement is usually different than the "naturally occurring" compounds.
| Descriptor ID |
D028421
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| MeSH Number(s) |
D10.251.355.255.100.375 D10.251.355.310.166.775 D10.251.355.411
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Isoprostanes".
Below are MeSH descriptors whose meaning is more specific than "Isoprostanes".
This graph shows the total number of publications written about "Isoprostanes" by people in this website by year, and whether "Isoprostanes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Isoprostanes" by people in Profiles.
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Tempol protects sleep-deprivation induced behavioral deficits in aggressive male Long-Evans rats. Neurosci Lett. 2016 Jan 26; 612:245-250.
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Major metabolite of F2-isoprostane in urine may be a more sensitive biomarker of oxidative stress than isoprostane itself. Am J Clin Nutr. 2012 Aug; 96(2):405-14.
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IL-17-mediated oxidative stress is an important stimulator of AT1-AA and hypertension during pregnancy. Am J Physiol Regul Integr Comp Physiol. 2012 Aug 15; 303(4):R353-8.
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C-reactive protein and other emerging blood biomarkers to optimize risk stratification of vulnerable patients. J Am Coll Cardiol. 2006 Apr 18; 47(8 Suppl):C19-31.
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In vivo rates of erythrocyte glutathione synthesis in adults with sickle cell disease. Am J Physiol Endocrinol Metab. 2006 Jul; 291(1):E73-9.