"Thromboxanes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Physiologically active compounds found in many organs of the body. They are formed in vivo from the prostaglandin endoperoxides and cause platelet aggregation, contraction of arteries, and other biological effects. Thromboxanes are important mediators of the actions of polyunsaturated fatty acids transformed by cyclooxygenase.
| Descriptor ID |
D013931
|
| MeSH Number(s) |
D10.251.355.255.100.825 D10.251.355.310.166.971
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Thromboxanes".
Below are MeSH descriptors whose meaning is more specific than "Thromboxanes".
This graph shows the total number of publications written about "Thromboxanes" by people in this website by year, and whether "Thromboxanes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Thromboxanes" by people in Profiles.
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Reprogramming Megakaryocytes for Controlled Release of Platelet-like Particles Carrying a Single-Chain Thromboxane A2 Receptor-G-Protein Complex with Therapeutic Potential. Cells. 2023 12 06; 12(24).
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Antitumor and Antiangiogenic Effects of Aspirin-PC in Ovarian Cancer. Mol Cancer Ther. 2016 12; 15(12):2894-2904.
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Mechanism of activation and functional role of protein kinase Ceta in human platelets. J Biol Chem. 2009 May 15; 284(20):13413-13421.
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New developments on thromboxane and prostacyclin modulators part I: thromboxane modulators. Curr Med Chem. 2004 May; 11(10):1223-41.
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Activated microglia are the principal glial source of thromboxane in the central nervous system. Neurochem Int. 1996 Jul; 29(1):65-76.
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Platelet regulatory prostanoids and platelet release products in sickle cell disease. Am J Hematol. 1992 May; 40(1):12-9.
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Effects of thromboxane synthase inhibition with CGS 13080 in human cyclosporine nephrotoxicity. Kidney Int. 1992 Jan; 41(1):199-205.
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Thromboxane stimulates synthesis of extracellular matrix proteins in vitro. Am J Physiol. 1991 Sep; 261(3 Pt 2):F488-94.
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High-protein feeding stimulates renal thromboxane production in rats with streptozocin-induced diabetes. J Lab Clin Med. 1989 Nov; 114(5):545-53.
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The role of thromboxane in two-kidney, one-clip Goldblatt hypertension in rats. Am J Physiol. 1989 Aug; 257(2 Pt 2):F190-6.