"Rats, Sprague-Dawley" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
| Descriptor ID |
D017207
|
| MeSH Number(s) |
B01.050.150.900.649.313.992.635.505.700.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Rats, Sprague-Dawley".
Below are MeSH descriptors whose meaning is more specific than "Rats, Sprague-Dawley".
This graph shows the total number of publications written about "Rats, Sprague-Dawley" by people in this website by year, and whether "Rats, Sprague-Dawley" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 17 | 17 |
| 1996 | 0 | 33 | 33 |
| 1997 | 0 | 40 | 40 |
| 1998 | 0 | 36 | 36 |
| 1999 | 0 | 35 | 35 |
| 2000 | 0 | 32 | 32 |
| 2001 | 0 | 30 | 30 |
| 2002 | 0 | 35 | 35 |
| 2003 | 0 | 47 | 47 |
| 2004 | 0 | 51 | 51 |
| 2005 | 0 | 57 | 57 |
| 2006 | 0 | 42 | 42 |
| 2007 | 0 | 48 | 48 |
| 2008 | 0 | 50 | 50 |
| 2009 | 0 | 56 | 56 |
| 2010 | 0 | 43 | 43 |
| 2011 | 0 | 42 | 42 |
| 2012 | 0 | 41 | 41 |
| 2013 | 0 | 38 | 38 |
| 2014 | 0 | 44 | 44 |
| 2015 | 0 | 35 | 35 |
| 2016 | 0 | 31 | 31 |
| 2017 | 0 | 30 | 30 |
| 2018 | 0 | 26 | 26 |
| 2019 | 0 | 27 | 27 |
| 2020 | 0 | 20 | 20 |
| 2021 | 0 | 12 | 12 |
| 2022 | 0 | 4 | 4 |
| 2023 | 0 | 5 | 5 |
| 2024 | 2 | 6 | 8 |
| 2025 | 1 | 1 | 2 |
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Below are the most recent publications written about "Rats, Sprague-Dawley" by people in Profiles.
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Ultra-low extracorporeal volume microfluidic leukapheresis is safe and effective in a rat model. Nat Commun. 2025 Feb 24; 16(1):1930.
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Integration of metabolomic and transcriptomic analyses reveals regulatory functions of the ChREBP transcription factor in energy metabolism. Cell Rep. 2025 Feb 25; 44(2):115278.
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Development of a UPLC-MS/MS Method for Bioanalysis of Ethoxysanguinarine and Its Application in Pharmacokinetic Study of Ethoxysanguinarine Nanoemulsion. Biomed Chromatogr. 2025 Jan; 39(1):e6055.
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IGF-1 impacts neocortical interneuron connectivity in epileptic spasm generation and resolution. Neurotherapeutics. 2025 Jan; 22(1):e00477.
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The long-term effects of limbic non-convulsive status epilepticus in peri-adolescent rats. Epilepsy Behav. 2024 Dec; 161:110086.
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ApoA-I binding protein (AIBP) regulates transient receptor potential vanilloid 1 (TRPV1) activity in rat dorsal root ganglion neurons by selective disruption of toll-like receptor 4 (TLR4)-lipid rafts. Brain Behav Immun. 2025 Jan; 123:644-655.
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Nerve injury augments Cacna2d1 transcription via CK2-mediated phosphorylation of the histone deacetylase HDAC2 in dorsal root ganglia. J Biol Chem. 2024 Nov; 300(11):107848.
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Bismuth-infused perivascular wrap facilitates delivery of mesenchymal stem cells and attenuation of neointimal hyperplasia in rat arteriovenous fistulas. Biomater Adv. 2025 Jan; 166:214052.
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The Estrogen Receptor-Related Orphan Receptors Regulate Autophagy through TFEB. Mol Pharmacol. 2024 Sep 17; 106(4):164-172.
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SORD-deficient rats develop a motor-predominant peripheral neuropathy unveiling novel pathophysiological insights. Brain. 2024 Sep 03; 147(9):3131-3143.