"Thromboxane A2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An unstable intermediate between the prostaglandin endoperoxides and thromboxane B2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (RCS).
| Descriptor ID |
D013928
|
| MeSH Number(s) |
D10.251.355.255.100.825.800 D10.251.355.310.166.971.800
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Thromboxane A2".
Below are MeSH descriptors whose meaning is more specific than "Thromboxane A2".
This graph shows the total number of publications written about "Thromboxane A2" by people in this website by year, and whether "Thromboxane A2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thromboxane A2" by people in Profiles.
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Increased Coronary Contraction to Thromboxane A2 in Cardiac Surgery Patients With Poorly Controlled Hypertension. J Surg Res. 2024 02; 294:249-256.
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Effects of higenamine and its 1-naphthyl analogs, YS-49 and YS-51, on platelet TXA2 synthesis and aggregation. Thromb Res. 2007; 120(1):81-6.
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Synergistic outside-in regulation of platelet activation by GPIIb/IIIa ligand-induced conformation and oligomerization. Thromb Res. 2001 Nov 15; 104(4):239-47.
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Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis. Circulation. 2000 Aug 22; 102(8):840-5.
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The anti-thrombotic effects of statins. J Am Coll Cardiol. 1999 Apr; 33(5):1305-7.
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Effects of selected vasoconstrictor agonists on isolated omental artery from premenopausal nonpregnant women and from normal and preeclamptic pregnant women. Am J Obstet Gynecol. 1996 Feb; 174(2):687-93.
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Meconium inhibits the contraction of umbilical vessels induced by the thromboxane A2 analog U46619. Am J Obstet Gynecol. 1995 Oct; 173(4):1075-8.
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The effect of lipid peroxides on isolated human umbilical artery contraction. Am J Obstet Gynecol. 1995 Mar; 172(3):825-30.
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Contractile effect of endothelin in human placental veins: role of endothelium prostaglandins and thromboxane. Am J Obstet Gynecol. 1993 Oct; 169(4):919-24.
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Thromboxane and prostacyclin differentially regulate murine extracellular matrix gene expression. Kidney Int. 1993 Jun; 43(6):1219-25.