Tissue Plasminogen Activator
"Tissue Plasminogen Activator" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.
| Descriptor ID |
D010959
|
| MeSH Number(s) |
D08.811.277.656.300.760.875 D08.811.277.656.959.350.875 D12.776.124.125.662.768 D23.119.970
|
| Concept/Terms |
Tissue Plasminogen Activator- Tissue Plasminogen Activator
- Plasminogen Activator, Tissue
- Tissue Activator D-44
- Tissue Activator D 44
- Tisokinase
- Tissue-Type Plasminogen Activator
- Tissue Type Plasminogen Activator
- TTPA
- T-Plasminogen Activator
- T Plasminogen Activator
- Alteplase
- Plasminogen Activator, Tissue-Type
- Plasminogen Activator, Tissue Type
Actilyse- Actilyse
- Lysatec rt-PA
- Lysatec rt PA
- Lysatec rtPA
|
Below are MeSH descriptors whose meaning is more general than "Tissue Plasminogen Activator".
Below are MeSH descriptors whose meaning is more specific than "Tissue Plasminogen Activator".
This graph shows the total number of publications written about "Tissue Plasminogen Activator" by people in this website by year, and whether "Tissue Plasminogen Activator" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1996 | 2 | 1 | 3 |
| 1997 | 2 | 0 | 2 |
| 1998 | 1 | 0 | 1 |
| 1999 | 0 | 3 | 3 |
| 2000 | 1 | 3 | 4 |
| 2001 | 3 | 7 | 10 |
| 2002 | 0 | 1 | 1 |
| 2003 | 2 | 0 | 2 |
| 2004 | 0 | 2 | 2 |
| 2005 | 3 | 1 | 4 |
| 2007 | 2 | 1 | 3 |
| 2008 | 3 | 0 | 3 |
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 5 | 0 | 5 |
| 2012 | 0 | 1 | 1 |
| 2013 | 5 | 3 | 8 |
| 2014 | 2 | 1 | 3 |
| 2015 | 6 | 2 | 8 |
| 2016 | 2 | 0 | 2 |
| 2017 | 4 | 4 | 8 |
| 2018 | 4 | 3 | 7 |
| 2019 | 3 | 2 | 5 |
| 2020 | 2 | 3 | 5 |
| 2021 | 4 | 3 | 7 |
| 2022 | 0 | 5 | 5 |
| 2023 | 0 | 3 | 3 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Tissue Plasminogen Activator" by people in Profiles.
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Outcomes of Pleural Space Infections in Patients With Indwelling Pleural Catheters for Active Malignancies. J Bronchology Interv Pulmonol. 2024 Apr 01; 31(2):155-159.
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Comparing Low- or Standard-Dose Alteplase in Endovascular Thrombectomy: Insights From a Nationwide Registry. Stroke. 2024 Mar; 55(3):532-540.
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a-Tocopherol Depletion Exacerbates Lipopolysaccharide-Induced Reduction of Grip Strength. J Nutr. 2024 02; 154(2):498-504.
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Strokes Averted by Intravenous Thrombolysis: A Secondary Analysis of a Prospective, Multicenter, Controlled Trial of Mobile Stroke Units. Ann Neurol. 2024 Feb; 95(2):347-361.
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Outcomes of patients with pre-existing disability managed by mobile stroke units: A sub-analysis of the BEST-MSU study. Int J Stroke. 2023 Dec; 18(10):1209-1218.
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Tissue plasminogen activator in left ventricular assist device-related intravascular hemolysis after failed augmented anticoagulation. Int J Artif Organs. 2022 Nov; 45(11):911-918.
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Thrombolysis Experience in Costa Rica Compared Against Individual Patient Data from two Randomized Controlled Trials. J Stroke Cerebrovasc Dis. 2022 Aug; 31(8):106599.
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Bleeding Risk With Combination Intrapleural Fibrinolytic and Enzyme Therapy in Pleural Infection: An International, Multicenter, Retrospective Cohort Study. Chest. 2022 Dec; 162(6):1384-1392.
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Efficacy of standardizing fibrinolytic therapy for parapneumonic effusion. Pediatr Radiol. 2022 11; 52(12):2413-2420.
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One-Year Costs Associated With the Veterans Affairs National TeleStroke Program. Value Health. 2022 06; 25(6):937-943.