"Trypsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine endopeptidase that is formed from TRYPSINOGEN in the pancreas. It is converted into its active form by ENTEROPEPTIDASE in the small intestine. It catalyzes hydrolysis of the carboxyl group of either arginine or lysine. EC 3.4.21.4.
| Descriptor ID |
D014357
|
| MeSH Number(s) |
D08.811.277.656.300.760.895 D08.811.277.656.959.350.895
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Trypsin".
Below are MeSH descriptors whose meaning is more specific than "Trypsin".
This graph shows the total number of publications written about "Trypsin" by people in this website by year, and whether "Trypsin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 2 | 3 |
| 2001 | 1 | 2 | 3 |
| 2002 | 0 | 1 | 1 |
| 2005 | 2 | 2 | 4 |
| 2006 | 0 | 3 | 3 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 2 | 2 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Trypsin" by people in Profiles.
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Pancreatic Cancer-Related Mutational Burden Is Not Increased in a Patient Cohort With Clinically Severe Chronic Pancreatitis. Clin Transl Gastroenterol. 2021 11 18; 12(11):e00431.
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Transgenic Expression of PRSS1R122H Sensitizes Mice to Pancreatitis. Gastroenterology. 2020 03; 158(4):1072-1082.e7.
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Early-Onset Acute Recurrent and Chronic Pancreatitis Is Associated with PRSS1 or CTRC Gene Mutations. J Pediatr. 2017 07; 186:95-100.
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Characterization of Lactobacillus salivarius strains B37 and B60 capable of inhibiting IL-8 production in Helicobacter pylori-stimulated gastric epithelial cells. BMC Microbiol. 2016 10 18; 16(1):242.
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Risk Factors Associated With Pediatric Acute Recurrent and Chronic Pancreatitis: Lessons From INSPPIRE. JAMA Pediatr. 2016 06 01; 170(6):562-9.
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Quantification of histone modifications by parallel-reaction monitoring: a method validation. Anal Chem. 2015 Oct 06; 87(19):10006-14.
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GPI-anchored protein complex, LY6K/TEX101, is required for sperm migration into the oviduct and male fertility in mice. Biol Reprod. 2014 Mar; 90(3):60.
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Absolute quantification of UGT1A1 in various tissues and cell lines using isotope label-free UPLC-MS/MS method determines its turnover number and correlates with its glucuronidation activities. J Pharm Biomed Anal. 2014 Jan; 88:180-90.
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Prediction of trypsin/molecular fragment binding affinities by free energy decomposition and empirical scores. J Comput Aided Mol Des. 2012 May; 26(5):647-59.
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Plasma membrane isolation using immobilized concanavalin A magnetic beads. Methods Mol Biol. 2012; 909:29-41.