"Chymases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of neutral serine proteases with CHYMOTRYPSIN-like activity. Chymases are primarily found in the SECRETORY GRANULES of MAST CELLS and are released during mast cell degranulation.
| Descriptor ID |
D053818
|
| MeSH Number(s) |
D08.811.277.656.300.760.103 D08.811.277.656.959.350.103
|
| Concept/Terms |
Chymases- Chymases
- Chymase
- Chymotrypsin-Like Proteases
- Chymotrypsin Like Proteases
- Chymotrypsin-Like Protease
- Chymotrypsin Like Protease
- Chymase-1
- Chymase 1
|
Below are MeSH descriptors whose meaning is more general than "Chymases".
Below are MeSH descriptors whose meaning is more specific than "Chymases".
This graph shows the total number of publications written about "Chymases" by people in this website by year, and whether "Chymases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chymases" by people in Profiles.
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Treponema denticola chymotrypsin-like protease as associated with HPV-negative oropharyngeal squamous cell carcinoma. Br J Cancer. 2018 07; 119(1):89-95.
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The inflammatory response after an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5. J Immunol. 2010 Dec 15; 185(12):7681-90.
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Increased myocardial susceptibility to repetitive ischemia with high-fat diet-induced obesity. Obesity (Silver Spring). 2008 Dec; 16(12):2593-600.
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The intracellular renin-angiotensin system: a new paradigm. Trends Endocrinol Metab. 2007 Jul; 18(5):208-14.
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High-glucose-induced regulation of intracellular ANG II synthesis and nuclear redistribution in cardiac myocytes. Am J Physiol Heart Circ Physiol. 2007 Aug; 293(2):H939-48.
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Mast cell-derived cathepsin g: a possible role in the adverse remodeling of the failing human heart. J Surg Res. 2007 Jun 15; 140(2):199-203.
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Advanced glycation end products activate a chymase-dependent angiotensin II-generating pathway in diabetic complications. Circulation. 2006 Mar 14; 113(10):1353-60.
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Chymase is upregulated in diabetic nephropathy: implications for an alternative pathway of angiotensin II-mediated diabetic renal and vascular disease. J Am Soc Nephrol. 2003 Jul; 14(7):1738-47.
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Mast cells and macrophages in normal C57/BL/6 mice. Histochem Cell Biol. 2002 Jul; 118(1):41-9.
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Mast cell distribution, activation, and phenotype in atherosclerotic lesions of human carotid arteries. J Pathol. 1997 May; 182(1):115-22.