"Myeloblastin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A polymorphonuclear leukocyte-derived serine protease that degrades proteins such as ELASTIN; FIBRONECTIN; LAMININ; VITRONECTIN; and COLLAGEN. It is named for its ability to control myeloid cell growth and differentiation.
| Descriptor ID |
D053146
|
| MeSH Number(s) |
D08.811.277.656.300.760.530 D08.811.277.656.959.350.530
|
| Concept/Terms |
Myeloblastin- Myeloblastin
- Leukocyte Proteinase 3
- Proteinase 3, Leukocyte
- Myeloblastin, Human
- Human Myeloblastin
- N-Proteinase 4
- N Proteinase 4
- PRTN3 Gene Protein
- Protein, PRTN3 Gene
- Neutrophil Proteinase 3, Human
- Neutrophil Proteinase 4
- Proteinase 4, Neutrophil
- Proteinase 3
- Wegener Autoantigen
- Autoantigen, Wegener
- C-ANCA Antigen
- Antigen, C-ANCA
- C ANCA Antigen
- Azurophil Granule Protein 7
- Neutrophil Proteinase 3
- Proteinase 3, Neutrophil
|
Below are MeSH descriptors whose meaning is more general than "Myeloblastin".
Below are MeSH descriptors whose meaning is more specific than "Myeloblastin".
This graph shows the total number of publications written about "Myeloblastin" by people in this website by year, and whether "Myeloblastin" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Myeloblastin" by people in Profiles.
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CRISPR-Cas9 mediated proteinase 3 autoantigen deletion as a treatment strategy for anti-neutrophil cytoplasmic autoantibody-associated vasculitis. Kidney Int. 2025 Jul; 108(1):145-149.
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Pulmonary manifestations and outcomes in paediatric ANCA-associated vasculitis: a single-centre experience. Rheumatology (Oxford). 2021 07 01; 60(7):3199-3208.
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Severe destructive nasopharyngeal granulomatosis with polyangiitis with superimposed skull base Pseudomonas aeruginosa osteomyelitis. BMJ Case Rep. 2017 Jul 19; 2017.
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Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis. Arthritis Rheumatol. 2017 05; 69(5):1054-1066.
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A Multibiomarker-Based Model for Estimating the Risk of Septic Acute Kidney Injury. Crit Care Med. 2015 Aug; 43(8):1646-53.
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Generation of multi-leukemia antigen-specific T cells to enhance the graft-versus-leukemia effect after allogeneic stem cell transplant. Leukemia. 2013 Jul; 27(7):1538-47.
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Broad cross-presentation of the hematopoietically derived PR1 antigen on solid tumors leads to susceptibility to PR1-targeted immunotherapy. J Immunol. 2012 Dec 01; 189(11):5476-84.
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The role of antigen cross-presentation from leukemia blasts on immunity to the leukemia-associated antigen PR1. J Immunother. 2012 May; 35(4):309-20.
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Relationship between markers of platelet activation and inflammation with disease activity in Wegener's granulomatosis. J Rheumatol. 2011 Jun; 38(6):1048-54.
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Adoptive transfer of PR1 cytotoxic T lymphocytes associated with reduced leukemia burden in a mouse acute myeloid leukemia xenograft model. Cytotherapy. 2010 Dec; 12(8):1056-62.