"Cathepsin G" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine protease found in the azurophil granules of NEUTROPHILS. It has an enzyme specificity similar to that of chymotrypsin C.
| Descriptor ID |
D056649
|
| MeSH Number(s) |
D08.811.277.656.224.350 D08.811.277.656.300.760.066 D08.811.277.656.959.350.066
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cathepsin G".
Below are MeSH descriptors whose meaning is more specific than "Cathepsin G".
This graph shows the total number of publications written about "Cathepsin G" by people in this website by year, and whether "Cathepsin G" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cathepsin G" by people in Profiles.
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Pro-inflammatory megakaryocyte gene expression in murine models of breast cancer. Sci Adv. 2022 10 14; 8(41):eabo5224.
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Stable depletion of RUNX1-ETO in Kasumi-1 cells induces expression and enhanced proteolytic activity of Cathepsin G and Neutrophil Elastase. PLoS One. 2019; 14(12):e0225977.
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Cathepsin G is broadly expressed in acute myeloid leukemia and is an effective immunotherapeutic target. Leukemia. 2017 01; 31(1):234-237.
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A novel HLA-A*0201 restricted peptide derived from cathepsin G is an effective immunotherapeutic target in acute myeloid leukemia. Clin Cancer Res. 2013 Jan 01; 19(1):247-57.
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Beneficial effects of a low-protein diet on host resistance to Paracoccidioides brasiliensis in mice. Nutrition. 2009 Sep; 25(9):954-63.
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Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100. Blood. 2009 Jun 11; 113(24):6206-14.
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Neutrophil Proteases Activate Eosinophil Function in vitro. Int Arch Allergy Immunol. 2008; 146 Suppl 1:16-21.
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Mast cell-derived cathepsin g: a possible role in the adverse remodeling of the failing human heart. J Surg Res. 2007 Jun 15; 140(2):199-203.
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In vitro induction of myeloid leukemia-specific CD4 and CD8 T cells by CD40 ligand-activated B cells gene modified to express primary granule proteins. Clin Cancer Res. 2005 Jun 15; 11(12):4495-503.
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Inhibition of serine proteinases plasmin, trypsin, subtilisin A, cathepsin G, and elastase by LEKTI: a kinetic analysis. Biochemistry. 2003 Apr 08; 42(13):3874-81.