"Peptide Hydrolases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Hydrolases that specifically cleave the peptide bonds found in PROTEINS and PEPTIDES. Examples of sub-subclasses for this group include EXOPEPTIDASES and ENDOPEPTIDASES.
| Descriptor ID |
D010447
|
| MeSH Number(s) |
D08.811.277.656
|
| Concept/Terms |
Peptide Hydrolases- Peptide Hydrolases
- Proteolytic Enzymes
- Proteases
- Proteinases
- Esteroproteases
- Peptidases
|
Below are MeSH descriptors whose meaning is more general than "Peptide Hydrolases".
Below are MeSH descriptors whose meaning is more specific than "Peptide Hydrolases".
This graph shows the total number of publications written about "Peptide Hydrolases" by people in this website by year, and whether "Peptide Hydrolases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 0 | 2 |
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 2 | 1 | 3 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 2 | 3 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 3 | 4 |
| 2003 | 4 | 6 | 10 |
| 2004 | 2 | 3 | 5 |
| 2005 | 4 | 6 | 10 |
| 2006 | 3 | 6 | 9 |
| 2007 | 4 | 5 | 9 |
| 2008 | 4 | 1 | 5 |
| 2009 | 4 | 6 | 10 |
| 2010 | 4 | 3 | 7 |
| 2011 | 7 | 3 | 10 |
| 2012 | 7 | 1 | 8 |
| 2013 | 6 | 1 | 7 |
| 2014 | 5 | 2 | 7 |
| 2015 | 2 | 1 | 3 |
| 2016 | 6 | 1 | 7 |
| 2017 | 3 | 0 | 3 |
| 2018 | 2 | 2 | 4 |
| 2019 | 5 | 0 | 5 |
| 2020 | 1 | 0 | 1 |
| 2021 | 2 | 3 | 5 |
| 2022 | 0 | 3 | 3 |
| 2023 | 1 | 4 | 5 |
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Below are the most recent publications written about "Peptide Hydrolases" by people in Profiles.
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Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia. Leukemia. 2024 Apr; 38(4):729-740.
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Evaluation of SARS-CoV-2 RNA Rebound After Nirmatrelvir/Ritonavir Treatment in Randomized, Double-Blind, Placebo-Controlled Trials - United States and International Sites, 2021-2022. MMWR Morb Mortal Wkly Rep. 2023 Dec 22; 72(51):1365-1370.
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Structure and function of SARS-CoV and SARS-CoV-2 main proteases and their inhibition: A comprehensive review. Eur J Med Chem. 2023 Nov 15; 260:115772.
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CUB domains are not required for OVCH2 function in sperm maturation in the mouse epididymis. Andrology. 2024 Mar; 12(3):682-697.
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Molecular dissection and testing of PRSS37 function through LC-MS/MS and the generation of a PRSS37 humanized mouse model. Sci Rep. 2023 07 14; 13(1):11374.
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Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors. Sci Adv. 2023 03 29; 9(13):eade8778.
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Safety and immunogenicity of the Na-APR-1 hookworm vaccine in infection-na?ve adults. Vaccine. 2022 10 06; 40(42):6084-6092.
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An Enzymatically Cleavable Tripeptide Linker for Maximizing the Therapeutic Index of Antibody-Drug Conjugates. Mol Cancer Ther. 2022 09 06; 21(9):1449-1461.
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Characterization of Calpain and Caspase-6-Generated Glial Fibrillary Acidic Protein Breakdown Products Following Traumatic Brain Injury and Astroglial Cell Injury. Int J Mol Sci. 2022 Aug 11; 23(16).
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Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites. Cell Host Microbe. 2022 10 12; 30(10):1354-1362.e6.