"Cathepsin C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A papain-like cysteine protease that has specificity for amino terminal dipeptides. The enzyme plays a role in the activation of several pro-inflammatory serine proteases by removal of their aminoterminal inhibitory dipeptides. Genetic mutations that cause loss of cathepsin C activity in humans are associated with PAPILLON-LEFEVRE DISEASE.
| Descriptor ID |
D020789
|
| MeSH Number(s) |
D08.811.277.656.224.130 D08.811.277.656.262.186 D08.811.277.656.350.350.100
|
| Concept/Terms |
Cathepsin C- Cathepsin C
- Dipeptidyl Peptidase I
- Dipeptidyl Transferase
- Dipeptidyl Aminopeptidase I
|
Below are MeSH descriptors whose meaning is more general than "Cathepsin C".
Below are MeSH descriptors whose meaning is more specific than "Cathepsin C".
This graph shows the total number of publications written about "Cathepsin C" by people in this website by year, and whether "Cathepsin C" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cathepsin C" by people in Profiles.
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Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes. Diabetes. 2016 Mar; 65(3):803-17.