"ADAM Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of membrane-anchored glycoproteins that contain a disintegrin and metalloprotease domain. They are responsible for the proteolytic cleavage of many transmembrane proteins and the release of their extracellular domain.
| Descriptor ID |
D051722
|
| MeSH Number(s) |
D08.811.277.656.675.374.102 D09.400.430.500 D12.776.395.033
|
| Concept/Terms |
ADAM Proteins- ADAM Proteins
- A Disintegrin and Metalloprotease Proteins
- ADAM (A Disintegrin and Metalloprotease) Proteins
|
Below are MeSH descriptors whose meaning is more general than "ADAM Proteins".
Below are MeSH descriptors whose meaning is more specific than "ADAM Proteins".
This graph shows the total number of publications written about "ADAM Proteins" by people in this website by year, and whether "ADAM Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 4 | 4 |
| 2004 | 0 | 5 | 5 |
| 2005 | 0 | 2 | 2 |
| 2006 | 3 | 0 | 3 |
| 2007 | 3 | 0 | 3 |
| 2008 | 3 | 1 | 4 |
| 2009 | 3 | 1 | 4 |
| 2010 | 3 | 2 | 5 |
| 2011 | 5 | 2 | 7 |
| 2012 | 4 | 1 | 5 |
| 2013 | 7 | 5 | 12 |
| 2014 | 6 | 0 | 6 |
| 2015 | 6 | 1 | 7 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 2 | 2 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
| 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "ADAM Proteins" by people in Profiles.
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Detection of novel duplication variant in ADAMTS13 gene using chromosomal microarray analysis. BMJ Case Rep. 2024 Jun 11; 17(6).
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Inhibition of ADAM9 promotes the selective degradation of KRAS and sensitizes pancreatic cancers to chemotherapy. Nat Cancer. 2024 Mar; 5(3):400-419.
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Recombinant ADAMTS-13 Improves Survival of Mice Subjected to Endotoxemia. Int J Mol Sci. 2023 Jul 22; 24(14).
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Adolescent acquired thrombotic thrombocytopenic purpura: An analysis of the Pediatric Health Information System database. Thromb Res. 2023 02; 222:63-67.
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Transcriptomic studies revealed pathophysiological impact of COVID-19 to predominant health conditions. Brief Bioinform. 2021 11 05; 22(6).
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Prss55 but not Prss51 is required for male fertility in mice?. Biol Reprod. 2020 08 04; 103(2):223-234.
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NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility. Science. 2020 06 05; 368(6495):1132-1135.
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A Disintegrin and Metalloproteinase Domain-8: A Novel Protective Proteinase in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2018 11 15; 198(10):1254-1267.
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Co-expression of sperm membrane proteins CMTM2A and CMTM2B is essential for ADAM3 localization and male fertility in mice. J Cell Sci. 2018 10 08; 131(19).
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Factors controlling sperm migration through the oviduct revealed by gene-modified mouse models. Exp Anim. 2018 May 10; 67(2):91-104.