"B-Cell Activating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tumor necrosis factor superfamily member that plays a role in the regulation of B-LYMPHOCYTE survival. It occurs as a membrane-bound protein that is cleaved to release an biologically active soluble form with specificity to TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR PROTEIN; B-CELL ACTIVATION FACTOR RECEPTOR; and B-CELL MATURATION ANTIGEN.
| Descriptor ID |
D053264
|
| MeSH Number(s) |
D12.644.276.374.750.061 D12.776.395.191 D12.776.467.374.750.061 D12.776.543.550.193 D23.529.374.750.061
|
| Concept/Terms |
B-Cell Activating Factor- B-Cell Activating Factor
- Activating Factor, B-Cell
- B-Lymphocyte Activating Factor
- Activating Factor, B-Lymphocyte
- B Lymphocyte Activating Factor
- THANK Protein
- BAFF Ligand
- BLyS Protein
- B Cell Activating Factor
- B Lymphocyte Stimulator
- CD257 Antigen
- Antigen, CD257
- Antigens, CD257
- TNF and APOL-Related Leukocyte Expressed Ligand 1
- TNF and APOL Related Leukocyte Expressed Ligand 1
- TNF Superfamily, Member 13b
- Tumor Necrosis Factor Ligand Superfamily Member 13b
- CD257 Antigens
- TNFSF13B Protein
- TALL-1 Protein
- TALL 1 Protein
|
Below are MeSH descriptors whose meaning is more general than "B-Cell Activating Factor".
Below are MeSH descriptors whose meaning is more specific than "B-Cell Activating Factor".
This graph shows the total number of publications written about "B-Cell Activating Factor" by people in this website by year, and whether "B-Cell Activating Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 2 | 1 | 3 |
| 2010 | 2 | 2 | 4 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "B-Cell Activating Factor" by people in Profiles.
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DYRK1a mediates BAFF-induced noncanonical NF-?B activation to promote autoimmunity and B-cell leukemogenesis. Blood. 2021 12 09; 138(23):2360-2371.
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B-cell activating factor (BAFF) plasma level at the time of chronic GvHD diagnosis is a potential predictor of non-relapse mortality. Bone Marrow Transplant. 2017 Jul; 52(7):1010-1015.
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B Cell-Activating Factor. An Orchestrator of Lymphoid Follicles in Severe Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2015 Sep 15; 192(6):695-705.
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Pharmacological and Protein Profiling Suggests Venetoclax (ABT-199) as Optimal Partner with Ibrutinib in Chronic Lymphocytic Leukemia. Clin Cancer Res. 2015 Aug 15; 21(16):3705-15.
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Cytokine BAFF released by Helicobacter pylori-infected macrophages triggers the Th17 response in human chronic gastritis. J Immunol. 2014 Dec 01; 193(11):5584-94.
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HIV-1 adenoviral vector vaccines expressing multi-trimeric BAFF and 4-1BBL enhance T cell mediated anti-viral immunity. PLoS One. 2014; 9(2):e90100.
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BLyS levels correlate with vaccine-induced antibody titers in patients with glioblastoma lymphodepleted by therapeutic temozolomide. Cancer Immunol Immunother. 2013 Jun; 62(6):983-7.
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The therapeutic effects of rGel/BLyS fusion toxin in in vitro and in vivo models of mantle cell lymphoma. Biochem Pharmacol. 2012 Aug 15; 84(4):451-8.
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Biodistribution, pharmacokinetics, and nuclear imaging studies of 111In-labeled rGel/BLyS fusion toxin in SCID mice bearing B cell lymphoma. Mol Imaging Biol. 2011 Aug; 13(4):721-9.
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Constitutive BR3 receptor signaling in diffuse, large B-cell lymphomas stabilizes nuclear factor-?B-inducing kinase while activating both canonical and alternative nuclear factor-?B pathways. Blood. 2011 Jan 06; 117(1):200-10.