Complement C1 Inhibitor Protein
"Complement C1 Inhibitor Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An endogenous 105-kDa plasma glycoprotein produced primarily by the LIVER and MONOCYTES. It inhibits a broad spectrum of proteases, including the COMPLEMENT C1R and the COMPLEMENT C1S proteases of the CLASSICAL COMPLEMENT PATHWAY, and the MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. C1-INH-deficient individuals suffer from HEREDITARY ANGIOEDEMA TYPES I AND II.
Descriptor ID |
D050718
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MeSH Number(s) |
D12.644.861.140.500 D12.776.124.486.274.920.250.500 D12.776.395.320 D12.776.872.140.500
|
Concept/Terms |
Complement C1 Inhibitor Protein- Complement C1 Inhibitor Protein
- Serpin Family G Member 1
- C1 Esterase Inhibitor
- Esterase Inhibitor, C1
- C1-Inhibitor Protein
- C1 Inhibitor Protein
- Serpin G1
- G1, Serpin
- Plasma Protease C1 Inhibitor
- Complement C1-Inhibitor Protein
- SERPING1
- C1-INH Protein
- C1 INH Protein
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Below are MeSH descriptors whose meaning is more general than "Complement C1 Inhibitor Protein".
Below are MeSH descriptors whose meaning is more specific than "Complement C1 Inhibitor Protein".
This graph shows the total number of publications written about "Complement C1 Inhibitor Protein" by people in this website by year, and whether "Complement C1 Inhibitor Protein" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
2022 | 0 | 1 | 1 |
2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Complement C1 Inhibitor Protein" by people in Profiles.
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An Overview of Hereditary Angioedema for the Primary Care Physician. Med Clin North Am. 2024 Jul; 108(4):747-755.
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Hereditary angioedema and COVID-19 during pregnancy: Two case reports. J Allergy Clin Immunol Pract. 2023 03; 11(3):961-962.
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Letter to 'Practical use of C1 esterase inhibitor concentrate for clinical amniotic fluid embolism'. J Obstet Gynaecol Res. 2019 01; 45(1):239.
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Idiopathic nonhistaminergic angioedema successfully treated with ecallantide, icatibant, and C1 esterase inhibitor replacement. J Allergy Clin Immunol Pract. 2014 Nov-Dec; 2(6):818-9.
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Delayed diagnosis of hereditary angioedema. Am J Med Sci. 2010 Jul; 340(1):82-3.
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Advances in basic and clinical immunology in 2006. J Allergy Clin Immunol. 2007 Aug; 120(2):263-70.
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Casein kinase II alpha subunit and C1-inhibitor are independent predictors of outcome in patients with squamous cell carcinoma of the lung. Clin Cancer Res. 2004 Sep 01; 10(17):5792-803.