"Anesthetics, Local" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
| Descriptor ID |
D000779
|
| MeSH Number(s) |
D27.505.696.277.100.200 D27.505.696.663.850.025 D27.505.954.427.210.100.200
|
| Concept/Terms |
Anesthetics, Local- Anesthetics, Local
- Local Anesthetics
- Conduction-Blocking Anesthetics
- Conduction Blocking Anesthetics
- Anesthetics, Conduction-Blocking
- Anesthetics, Conduction Blocking
|
Below are MeSH descriptors whose meaning is more general than "Anesthetics, Local".
Below are MeSH descriptors whose meaning is more specific than "Anesthetics, Local".
This graph shows the total number of publications written about "Anesthetics, Local" by people in this website by year, and whether "Anesthetics, Local" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 1 | 2 |
| 2001 | 2 | 0 | 2 |
| 2002 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 2 | 1 | 3 |
| 2006 | 0 | 1 | 1 |
| 2007 | 2 | 1 | 3 |
| 2008 | 2 | 2 | 4 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 3 | 2 | 5 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 1 | 2 |
| 2016 | 2 | 3 | 5 |
| 2018 | 0 | 2 | 2 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 3 | 3 |
| 2022 | 2 | 2 | 4 |
| 2023 | 1 | 1 | 2 |
| 2024 | 4 | 1 | 5 |
| 2025 | 5 | 0 | 5 |
| 2026 | 1 | 1 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Anesthetics, Local" by people in Profiles.
-
Perioperative guidelines for peripheral nerve blocks. Nursing. 2026 Feb 01; 56(2):15-22.
-
Local Delivery of Non-opioid Analgesic Microparticles to Modulate Post-surgical Pain. Pharm Res. 2025 Sep; 42(9):1573-1585.
-
Managing Donor Site Pain After Alveolar Bone Grafting: A Comparative Analysis of Liposomal Bupivacaine (Exparel), Bupivacaine-Soaked Gelfoam, and ON-Q Ropivacaine. J Craniofac Surg. 2025 06 01; 36(4):1291-1296.
-
Anticipation, perception, and recollection of acute pain from local anesthesia injection prior to Mohs surgery. Arch Dermatol Res. 2025 Feb 25; 317(1):490.
-
Mitigating the Risk of Local Anesthetic Toxicity with Truncal Blocks. A A Pract. 2024 Sep 01; 18(9):e01847.
-
Efficacy of 0.25% Lidocaine Versus 0.5% Lidocaine in Dermatologic Surgery: A Double-Blind, Randomized Controlled Trial. Dermatol Surg. 2025 01 01; 51(1):30-33.
-
Clinical impact of diagnostic image-guided injections for musculoskeletal pain work-up in adolescent and adult patients at a children's hospital: initial results. Skeletal Radiol. 2024 Aug; 53(8):1573-1582.
-
Liposomal Bupivacaine Use During Orthognathic Surgery in Cleft Lip and Palate Patients. J Craniofac Surg. 2024 Mar-Apr 01; 35(2):464-468.
-
The risk of local anesthetic systemic toxicity is increased in patients with critically low weight and muscle mass. Rev Port Cardiol. 2024 05; 43(5):295-296.
-
Laparoscopic administration of bupivacaine at the uterosacral ligaments during benign laparoscopic and robotic hysterectomy: a randomized controlled trial. Am J Obstet Gynecol. 2023 11; 229(5):526.e1-526.e14.