"Phosphotyrosine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An amino acid that occurs in endogenous proteins. Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly in cell growth control and carcinogenesis.
| Descriptor ID |
D019000
|
| MeSH Number(s) |
D12.125.072.050.875.750 D12.125.740.740
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Phosphotyrosine".
Below are MeSH descriptors whose meaning is more specific than "Phosphotyrosine".
This graph shows the total number of publications written about "Phosphotyrosine" by people in this website by year, and whether "Phosphotyrosine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2002 | 0 | 2 | 2 |
| 2004 | 1 | 1 | 2 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 1 | 1 | 2 |
| 2016 | 1 | 2 | 3 |
| 2020 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Phosphotyrosine" by people in Profiles.
-
The intrinsic substrate specificity of the human tyrosine kinome. Nature. 2024 May; 629(8014):1174-1181.
-
JAK2 regulates Nav1.6 channel function via FGF14Y158 phosphorylation. Biochim Biophys Acta Mol Cell Res. 2020 10; 1867(10):118786.
-
Regulation of SOX11 expression through CCND1 and STAT3 in mantle cell lymphoma. Blood. 2019 01 24; 133(4):306-318.
-
Helicobacter pylori VacA, acting through receptor protein tyrosine phosphatase a, is crucial for CagA phosphorylation in human duodenum carcinoma cell line AZ-521. Dis Model Mech. 2016 12 01; 9(12):1473-1481.
-
Protein stabilization improves STAT3 function in autosomal dominant hyper-IgE syndrome. Blood. 2016 12 29; 128(26):3061-3072.
-
Systematic analysis of phosphotyrosine antibodies recognizing single phosphorylated EPIYA-motifs in CagA of East Asian-type Helicobacter pylori strains. BMC Microbiol. 2016 09 02; 16(1):201.
-
Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease. PLoS Biol. 2014 Aug; 12(8):e1001923.
-
Systematic analysis of phosphotyrosine antibodies recognizing single phosphorylated EPIYA-motifs in CagA of Western-type Helicobacter pylori strains. PLoS One. 2014; 9(5):e96488.
-
EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2. Nature. 2013 May 16; 497(7449):383-7.
-
Protein tyrosine phosphatase 1B is a key regulator of IFNAR1 endocytosis and a target for antiviral therapies. Proc Natl Acad Sci U S A. 2012 Nov 20; 109(47):19226-31.