Procollagen N-Endopeptidase
"Procollagen N-Endopeptidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An extracellular endopeptidase which excises a block of peptides at the amino terminal, nonhelical region of the procollagen molecule with the formation of collagen. Absence or deficiency of the enzyme causes accumulation of procollagen which results in the inherited connective tissue disorder--dermatosparaxis. EC 3.4.24.14.
| Descriptor ID |
D011348
|
| MeSH Number(s) |
D08.811.277.656.300.480.664 D08.811.277.656.675.374.664
|
| Concept/Terms |
Procollagen N-Endopeptidase- Procollagen N-Endopeptidase
- Procollagen N Endopeptidase
- Procollagen N-Proteinase
- Procollagen N Proteinase
- Procollagen Peptidase
|
Below are MeSH descriptors whose meaning is more general than "Procollagen N-Endopeptidase".
Below are MeSH descriptors whose meaning is more specific than "Procollagen N-Endopeptidase".
This graph shows the total number of publications written about "Procollagen N-Endopeptidase" by people in this website by year, and whether "Procollagen N-Endopeptidase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Procollagen N-Endopeptidase" by people in Profiles.
-
Biallelic mutation of FBXL7 suggests a novel form of Hennekam syndrome. Am J Med Genet A. 2020 01; 182(1):189-194.
-
Genetic variants in the metzincin metallopeptidase family genes predict melanoma survival. Mol Carcinog. 2018 Jan; 57(1):22-31.
-
Rare and low-frequency coding variants alter human adult height. Nature. 2017 02 09; 542(7640):186-190.
-
ADAMTS4 and ADAMTS5 knockout mice are protected from versican but not aggrecan or brevican proteolysis during spinal cord injury. Biomed Res Int. 2014; 2014:693746.
-
ADAMTS-1 and ADAMTS-4 levels are elevated in thoracic aortic aneurysms and dissections. Ann Thorac Surg. 2013 Feb; 95(2):570-7.
-
Partially redundant functions of Adamts1 and Adamts4 in the perinatal development of the renal medulla. Dev Dyn. 2011 Jul; 240(7):1806-14.
-
Regulated expression of ADAMTS family members in follicles and cumulus oocyte complexes: evidence for specific and redundant patterns during ovulation. Biol Reprod. 2005 May; 72(5):1241-55.