Lupus Coagulation Inhibitor
"Lupus Coagulation Inhibitor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications.
| Descriptor ID |
D016682
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| MeSH Number(s) |
D12.776.124.486.485.114.323.210.600 D12.776.124.790.651.114.323.210.600 D12.776.377.715.548.114.323.210.600 D23.113.475
|
| Concept/Terms |
Lupus Coagulation Inhibitor- Lupus Coagulation Inhibitor
- Inhibitor, Lupus Coagulation
- Coagulation Inhibitor, Lupus
- Lupus Anticoagulant
- Anticoagulant, Lupus
|
Below are MeSH descriptors whose meaning is more general than "Lupus Coagulation Inhibitor".
Below are MeSH descriptors whose meaning is more specific than "Lupus Coagulation Inhibitor".
This graph shows the total number of publications written about "Lupus Coagulation Inhibitor" by people in this website by year, and whether "Lupus Coagulation Inhibitor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2007 | 2 | 0 | 2 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lupus Coagulation Inhibitor" by people in Profiles.
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Systematic review of observational studies reporting antiphospholipid antibodies in patients with solid tumors. Blood Adv. 2020 04 28; 4(8):1746-1755.
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Relation of antiphospholipid antibodies to postmortem brain infarcts in older people. Circulation. 2015 Jan 13; 131(2):182-9.
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Neurological manifestations of the antiphospholipid syndrome: risk assessments and evidence-based medicine. Int J Clin Pract. 2007 Sep; 61(9):1561-8.
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Lupus anticoagulant assays: questions answered and to be answered. Arch Pathol Lab Med. 2007 Jun; 131(6):885-9.
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Protein S deficiency in the presence of weak lupus anticoagulant resulting in right ventricular thrombosis. Clin Adv Hematol Oncol. 2004 Mar; 2(3):179.
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Adrenal involvement in the antiphospholipid syndrome: clinical and immunologic characteristics of 86 patients. Medicine (Baltimore). 2003 Mar; 82(2):106-18.
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Hypoprothrombinemia and severe hemorrhage associated with a lupus anticoagulant. J Pediatr. 1993 Dec; 123(6):937-9.