Platelet-Derived Growth Factor
"Platelet-Derived Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication.
| Descriptor ID |
D010982
|
| MeSH Number(s) |
D12.644.276.910 D12.776.124.625 D12.776.467.910 D23.529.910
|
| Concept/Terms |
Platelet-Derived Growth Factor- Platelet-Derived Growth Factor
- Factor, Platelet-Derived Growth
- Growth Factor, Platelet-Derived
- Platelet Derived Growth Factor
|
Below are MeSH descriptors whose meaning is more general than "Platelet-Derived Growth Factor".
Below are MeSH descriptors whose meaning is more specific than "Platelet-Derived Growth Factor".
This graph shows the total number of publications written about "Platelet-Derived Growth Factor" by people in this website by year, and whether "Platelet-Derived Growth Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 3 | 0 | 3 |
| 1998 | 0 | 3 | 3 |
| 1999 | 1 | 1 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 1 | 2 |
| 2002 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 2 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 1 | 2 |
| 2023 | 1 | 0 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Platelet-Derived Growth Factor" by people in Profiles.
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Metastatic medulloblastoma remodels the local leptomeningeal microenvironment to promote further metastatic colonization and growth. Nat Cell Biol. 2025 May; 27(5):863-874.
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Positive regulatory loop of platelet-derived growth factor DD-induced STAT3 activation is associated with poor prognosis in advanced urothelial carcinoma. Biochem Biophys Res Commun. 2023 10 08; 676:165-170.
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Improved Biomarker and Imaging Analysis for Characterizing Progressive Cardiac Fibrosis in a Mouse Model of Chronic Chagasic Cardiomyopathy. J Am Heart Assoc. 2019 11 19; 8(22):e013365.
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Effects of Aspirin on Growth Factor Release From Freshly Isolated Leukocyte-Rich Platelet-Rich Plasma in Healthy Men: A Prospective Fixed-Sequence Controlled Laboratory Study. Am J Sports Med. 2019 04; 47(5):1223-1229.
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A recombinant lentiviral PDGF-driven mouse model of proneural glioblastoma. Neuro Oncol. 2018 02 19; 20(3):332-342.
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The role of myeloid cell-derived PDGF-B in neotissue formation in a tissue-engineered vascular graft. Regen Med. 2017 04; 12(3):249-261.
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FoxM1 Drives a Feed-Forward STAT3-Activation Signaling Loop That Promotes the Self-Renewal and Tumorigenicity of Glioblastoma Stem-like Cells. Cancer Res. 2015 Jun 01; 75(11):2337-48.
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Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development. Dev Biol. 2014 Aug 15; 392(2):324-33.
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Profibrotic TGF? responses require the cooperative action of PDGF and ErbB receptor tyrosine kinases. FASEB J. 2013 Nov; 27(11):4444-54.
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BMP-specific SMADs function as novel repressors of PDGFA and modulate its expression in ovarian granulosa cells and tumors. Oncogene. 2013 Aug 15; 32(33):3877-85.