"Wnt Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.
| Descriptor ID |
D051153
|
| MeSH Number(s) |
D12.776.467.984 D23.529.984
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Wnt Proteins".
Below are MeSH descriptors whose meaning is more specific than "Wnt Proteins".
This graph shows the total number of publications written about "Wnt Proteins" by people in this website by year, and whether "Wnt Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 3 | 3 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 3 | 4 |
| 2006 | 3 | 1 | 4 |
| 2007 | 6 | 4 | 10 |
| 2008 | 3 | 4 | 7 |
| 2009 | 4 | 5 | 9 |
| 2010 | 6 | 5 | 11 |
| 2011 | 8 | 5 | 13 |
| 2012 | 2 | 2 | 4 |
| 2013 | 6 | 4 | 10 |
| 2014 | 1 | 5 | 6 |
| 2015 | 2 | 3 | 5 |
| 2016 | 0 | 3 | 3 |
| 2017 | 2 | 2 | 4 |
| 2018 | 2 | 4 | 6 |
| 2019 | 1 | 3 | 4 |
| 2020 | 1 | 3 | 4 |
| 2021 | 2 | 2 | 4 |
| 2025 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Wnt Proteins" by people in Profiles.
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PRDM16 Enhances Osteoblastogenic RUNX2 via Canonical WNT10b/?-CATENIN Pathway in Testosterone-Treated Hypogonadal Men. Biomolecules. 2025 01 08; 15(1).
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A Human Pleiotropic Multiorgan Condition Caused by Deficient Wnt Secretion. N Engl J Med. 2021 09 30; 385(14):1292-1301.
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Yap Promotes Noncanonical Wnt Signals From Cardiomyocytes for Heart Regeneration. Circ Res. 2021 10; 129(8):782-797.
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A Wnt-Independent LGR4-EGFR Signaling Axis in Cancer Metastasis. Cancer Res. 2021 09 01; 81(17):4441-4454.
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Perturbations of genes essential for M?llerian duct and W?lffian duct development in Mayer-Rokitansky-K?ster-Hauser syndrome. Am J Hum Genet. 2021 02 04; 108(2):337-345.
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Accumulation of Molecular Aberrations Distinctive to Hepatocellular Carcinoma Progression. Cancer Res. 2020 09 15; 80(18):3810-3819.
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Pediatric Posterior Fossa Medulloblastoma: The Role of Diffusion Imaging in Identifying Molecular Groups. J Neuroimaging. 2020 07; 30(4):503-511.
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Redundant and additive functions of the four Lef/Tcf transcription factors in lung epithelial progenitors. Proc Natl Acad Sci U S A. 2020 06 02; 117(22):12182-12191.
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Haploinsufficiency of Casitas B-Lineage Lymphoma Augments the Progression of Colon Cancer in the Background of Adenomatous Polyposis Coli Inactivation. Am J Pathol. 2020 03; 190(3):602-613.
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Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study. Hum Mol Genet. 2019 08 15; 28(16):2659-2674.