"Wnt4 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A Wnt protein that is involved in regulating multiple developmental processes such as the formation of the KIDNEY; ADRENAL GLANDS; MAMMARY GLANDS; the PITUITARY GLAND; and the female reproductive system. Defects in WNT4 are a cause of ROKITANSKY KUSTER HAUSER SYNDROME.
| Descriptor ID |
D060528
|
| MeSH Number(s) |
D12.776.467.984.400 D23.529.984.400
|
| Concept/Terms |
Wnt4 Protein- Wnt4 Protein
- Wnt-4 Proteins
- Wnt 4 Proteins
- Wnt-4 Protein
- Wnt 4 Protein
|
Below are MeSH descriptors whose meaning is more general than "Wnt4 Protein".
Below are MeSH descriptors whose meaning is more specific than "Wnt4 Protein".
This graph shows the total number of publications written about "Wnt4 Protein" by people in this website by year, and whether "Wnt4 Protein" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 2 | 2 |
| 2010 | 0 | 3 | 3 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 1 | 2 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Wnt4 Protein" by people in Profiles.
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A WNT4- and DKK3-driven canonical to noncanonical Wnt signaling switch controls multiciliogenesis. J Cell Sci. 2023 08 15; 136(16).
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Loss of WNT4 in the gubernaculum causes unilateral cryptorchidism and fertility defects. Development. 2022 12 01; 149(23).
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Mice Lacking Wnt9a or Wnt4 Are Prone to Develop Spontaneous Osteoarthritis With Age and Display Alteration in Either the Trabecular or Cortical Bone Compartment. J Bone Miner Res. 2022 07; 37(7):1335-1351.
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E2F1 regulates testicular descent and controls spermatogenesis by influencing WNT4 signaling. Development. 2021 01 13; 148(1).
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Microtubule depolymerization attenuates WNT4/CaMKIIa signaling in mouse uterus and leads to implantation failure. Reproduction. 2019 07; 158(1):47-59.
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Targeted ablation of Wnt4 and Wnt5a in M?llerian duct mesenchyme impedes endometrial gland development and causes partial M?llerian agenesis. Biol Reprod. 2019 01 01; 100(1):49-60.
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Growth regulation by estrogen in breast cancer 1 (GREB1) is a novel progesterone-responsive gene required for human endometrial stromal decidualization. Mol Hum Reprod. 2017 09 01; 23(9):646-653.
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The epidermal growth factor receptor critically regulates endometrial function during early pregnancy. PLoS Genet. 2014 Jun; 10(6):e1004451.
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The Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans. PLoS Genet. 2013; 9(8):e1003645.
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CTNNB1 signaling in sertoli cells downregulates spermatogonial stem cell activity via WNT4. PLoS One. 2012; 7(1):e29764.